Androgen receptor activity in T cells limits checkpoint blockade efficacy X Guan*, F Polesso* (co-first), C Wang* (co-first), A Sehrawat, ... Nature, 1-6, 2022 | 194 | 2022 |
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data D Sun, X Guan, AE Moran, LY Wu, DZ Qian, P Schedin, MS Dai, ... Nature biotechnology 40 (4), 527-538, 2022 | 154 | 2022 |
Genomic drivers of poor prognosis and enzalutamide resistance in metastatic castration-resistant prostate cancer WS Chen, R Aggarwal, L Zhang, SG Zhao, GV Thomas, TM Beer, ... European urology 76 (5), 562-571, 2019 | 125 | 2019 |
Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance JJ Alumkal, D Sun, E Lu, TM Beer, GV Thomas, E Latour, R Aggarwal, ... Proceedings of the National Academy of Sciences 117 (22), 12315-12323, 2020 | 100 | 2020 |
Stromal senescence by prolonged CDK4/6 inhibition potentiates tumor growth X Guan, KM LaPak, RC Hennessey, YY Christina, R Shakya, J Zhang, ... Molecular Cancer Research, molcanres. 0319.2016, 2016 | 85 | 2016 |
BET bromodomain inhibition blocks an AR-repressed, E2F1-activated treatment-emergent neuroendocrine prostate cancer lineage plasticity program DH Kim, D Sun, WK Storck, K Welker Leng, C Jenkins, DJ Coleman, ... Clinical Cancer Research 27 (17), 4923-4936, 2021 | 44 | 2021 |
T cell transcriptional profiling and immunophenotyping uncover LAG3 as a potential significant target of immune modulation in multiple myeloma F Lucas, M Pennell, Y Huang, DM Benson, YA Efebera, M Chaudhry, ... Biology of Blood and Marrow Transplantation 26 (1), 7-15, 2020 | 44 | 2020 |
Wheat hypersensitive-induced reaction genes TaHIR1 and TaHIR3 are involved in response to stripe rust fungus infection and abiotic stresses Y Duan, J Guo, X Shi, X Guan, F Liu, P Bai, L Huang, Z Kang Plant cell reports 32, 273-283, 2013 | 42 | 2013 |
Biocontrol efficiency of Meyerozyma guilliermondii Y-1 against apple postharvest decay caused by Botryosphaeria dothidea and the possible mechanisms of action Y Huang, C Sun, X Guan, S Lian, B Li, C Wang International Journal of Food Microbiology 338, 108957, 2021 | 37 | 2021 |
The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer A Chow, FZ Uddin, M Liu, A Dobrin, BY Nabet, L Mangarin, Y Lavin, ... Immunity 56 (1), 93-106. e6, 2023 | 30 | 2023 |
Butylated Hydroxytoluene Induced Resistance Against Botryosphaeria dothidea in Apple Fruit Y Huang, C Sun, X Guan, S Lian, B Li, C Wang Frontiers in Microbiology 11, 599062, 2021 | 24 | 2021 |
Pregnancy and weaning regulate human maternal liver size and function A Q. Bartlett, KK Vesco, JQ Purnell, M Francisco, E Goddard, X Guan, ... Proceedings of the National Academy of Sciences 118 (48), e2107269118, 2021 | 23 | 2021 |
Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity TC Westbrook*, X Guan* (co-first), E Rodansky, D Flores, CJ Liu, ... Nature Communications 13 (1), 1-13, 2022 | 17 | 2022 |
A distinct innate immune signature of early onset colorectal cancer IH Gardner, R Siddharthan, K Watson, E Dewey, R Ruhl, S Khou, X Guan, ... Immunohorizons 5 (6), 489-499, 2021 | 17 | 2021 |
Increased nuclear but not cytoplasmic activities of CELF1 protein leads to muscle wasting DC Cox, X Guan, Z Xia, TA Cooper Human molecular genetics 29 (10), 1729-1744, 2020 | 16 | 2020 |
658MO Cisplatin (cis)-related immunomodulation and efficacy with atezolizumab (atezo)+ cis-vs carboplatin (carbo)-based chemotherapy (chemo) in metastatic urothelial cancer (mUC) MD Galsky, X Guan, R Banchereau, L Wang, J Zhu, H Yu, D Rishipathak, ... Annals of Oncology 32, S682-S683, 2021 | 15 | 2021 |
Agrobacterium tumefaciens-mediated transformation of Valsa mali: an efficient tool for random insertion mutagenesis C Wang, X Guan, H Wang, G Li, X Dong, G Wang, B Li The Scientific World Journal 2013, 2013 | 14 | 2013 |
Reversible cardiac disease features in an inducible CUG repeat RNA–expressing mouse model of myotonic dystrophy AN Rao, HM Campbell, X Guan, TA Word, XHT Wehrens, Z Xia, ... JCI insight 6 (5), 2021 | 13 | 2021 |
Single-cell analysis reveals clonally expanded tumor-associated CD57+ CD8 T cells are enriched in the periphery of patients with metastatic urothelial cancer responding to PD … M Fehlings, L Kim, X Guan, K Yuen, A Tafazzol, S Sanjabi, OA Zill, ... Journal for Immunotherapy of Cancer 10 (8), 2022 | 12 | 2022 |
A type I MADS-box gene is differentially expressed in wheat in response to infection by the stripe rust fungus J Guo, XX Shi, JS Zhang, YH Duan, PF Bai, XN Guan, ZS Kang Biologia plantarum 57, 540-546, 2013 | 12 | 2013 |