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Botond Szilagyi
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Integrated continuous pharmaceutical technologies—a review
A Domokos, B Nagy, B Szilagyi, G Marosi, ZK Nagy
Organic Process Research & Development 25 (4), 721-739, 2021
1062021
End-to-end continuous manufacturing of conventional compressed tablets: From flow synthesis to tableting through integrated crystallization and filtration
A Domokos, B Nagy, M Gyürkés, A Farkas, K Tacsi, H Pataki, YC Liu, ...
International journal of pharmaceutics 581, 119297, 2020
682020
Real-time image processing based online feedback control system for cooling batch crystallization
A Borsos, B Szilagyi, PS Agachi, ZK Nagy
Organic Process Research & Development 21 (4), 511-519, 2017
662017
Application of model-free and model-based quality-by-control (QbC) for the efficient design of pharmaceutical crystallization processes
B Szilagyi, A Eren, JL Quon, CD Papageorgiou, ZK Nagy
Crystal Growth & Design 20 (6), 3979-3996, 2020
562020
Graphical processing unit (GPU) acceleration for numerical solution of population balance models using high resolution finite volume algorithm
B Szilágyi, ZK Nagy
Computers & Chemical Engineering 91, 167-181, 2016
502016
Experimental implementation of a Quality-by-Control (QbC) framework using a mechanistic PBM-based nonlinear model predictive control involving chord length distribution …
B Szilágyi, Á Borsos, K Pal, ZK Nagy
Chemical Engineering Science 195, 335-346, 2019
472019
High-throughput screening of organic reactions in microdroplets using desorption electrospray ionization mass spectrometry (DESI-MS): hardware and software implementation
TJP Sobreira, L Avramova, B Szilagyi, DL Logsdon, BP Loren, Z Jaman, ...
Analytical Methods 12 (28), 3654-3669, 2020
382020
Systematic model identification and optimization-based active polymorphic control of crystallization processes
E Simone, B Szilagyi, ZK Nagy
Chemical Engineering Science 174, 374-386, 2017
382017
Model-based analysis of stirred cooling crystallizer of high aspect ratio crystals with linear and nonlinear breakage
B Szilágyi, BG Lakatos
Computers & Chemical Engineering 98, 180-196, 2017
372017
Modeling of pharmaceutical filtration and continuous integrated crystallization-filtration processes
B Nagy, B Szilágyi, A Domokos, K Tacsi, H Pataki, G Marosi, ZK Nagy, ...
Chemical Engineering Journal 413, 127566, 2021
352021
Population balance modeling and optimization of an integrated batch crystallizer–wet mill system for crystal size distribution control
B Szilagyi, ZK Nagy
Crystal Growth & Design 18 (3), 1415-1424, 2018
342018
Chord length distribution based modeling and adaptive model predictive control of batch crystallization processes using high fidelity full population balance models
B Szilágyi, PS Agachi, ZK Nagy
Industrial & Engineering Chemistry Research 57 (9), 3320-3332, 2018
312018
Experimental investigation of an integrated crystallization and wet-milling system with temperature cycling to control the size and aspect ratio of needle-shaped pharmaceutical …
A Eren, B Szilagyi, JL Quon, CD Papageorgiou, ZK Nagy
Crystal Growth & Design 21 (7), 3981-3993, 2021
292021
High-throughput experimentation and continuous flow evaluation of nucleophilic aromatic substitution reactions
Z Jaman, DL Logsdon, B Szilágyi, TJP Sobreira, D Aremu, L Avramova, ...
ACS Combinatorial Science 22 (4), 184-196, 2020
292020
Aspect ratio distribution and chord length distribution driven modeling of crystallization of two-dimensional crystals for real-time model-based applications
B Szilagyi, ZK Nagy
Crystal Growth & Design 18 (9), 5311-5321, 2018
292018
Reaction precipitation of amorphous calcium phosphate: population balance modelling and kinetics
B Szilágyi, N Muntean, R Barabás, O Ponta, BG Lakatos
Chemical Engineering Research and Design 93, 278-286, 2015
272015
Dynamic flowsheet model development and digital design of continuous pharmaceutical manufacturing with dissolution modeling of the final product
B Nagy, B Szilágyi, A Domokos, B Vészi, K Tacsi, Z Rapi, H Pataki, ...
Chemical Engineering Journal 419, 129947, 2021
242021
2. Model predictive control
PS Agachi, MV Cristea, AA Csavdari, B Szilagyi
Advanced process engineering control. De Gruyter, 32-74, 2016
242016
Numerical analysis of crystallization of high aspect ratio crystals with breakage
B Szilágyi, PŞ Agachi, BG Lakatos
Powder Technology 283, 152-162, 2015
242015
Polymorphic control and scale-up strategy for antisolvent crystallization using direct nucleation control
I Ostergaard, B Szilagyi, HL De Diego, H Qu, ZK Nagy
Crystal Growth & Design 20 (4), 2683-2697, 2020
232020
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