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Richard T Eastman
Richard T Eastman
NIH/National Center for Advancing Translational Sciences
Verified email at nih.gov
Title
Cited by
Cited by
Year
Remdesivir: a review of its discovery and development leading to emergency use authorization for treatment of COVID-19
RT Eastman, JS Roth, KR Brimacombe, A Simeonov, M Shen, S Patnaik, ...
ACS central Science 6 (5), 672-683, 2020
6832020
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
RT Eastman, DA Fidock
Nature Reviews Microbiology 7 (12), 864-874, 2009
5892009
Drug-resistant malaria: molecular mechanisms and implications for public health
I Petersen, R Eastman, M Lanzer
FEBS letters 585 (11), 1551-1562, 2011
3712011
Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue
SH Adjalley, GL Johnston, T Li, RT Eastman, EH Ekland, AG Eappen, ...
Proceedings of the National Academy of Sciences 108 (47), E1214-E1223, 2011
3042011
Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics
MH Gelb, WC Van Voorhis, FS Buckner, K Yokoyama, R Eastman, ...
Molecular and biochemical parasitology 126 (2), 155-163, 2003
1742003
Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured Plasmodium falciparum Parasites
RT Eastman, NV Dharia, EA Winzeler, DA Fidock
Antimicrobial agents and chemotherapy 55 (8), 3908-3916, 2011
1472011
Thematic review series: lipid posttranslational modifications. Fighting parasitic disease by blocking protein farnesylation
RT Eastman, FS Buckner, K Yokoyama, MH Gelb, WC Van Voorhis
Journal of lipid research 47 (2), 233-240, 2006
1472006
Recent highlights in antimalarial drug resistance and chemotherapy research
DA Fidock, RT Eastman, SA Ward, SR Meshnick
Trends in parasitology 24 (12), 537-544, 2008
1282008
Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate
AM Lisewski, JP Quiros, CL Ng, AK Adikesavan, K Miura, N Putluri, ...
Cell 158 (4), 916-928, 2014
1272014
High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations
BT Mott, RT Eastman, R Guha, KS Sherlach, A Siriwardana, P Shinn, ...
Scientific reports 5 (1), 1-14, 2015
1032015
Trypanosoma cruzi Inactivation in Human Platelet Concentrates and Plasma by a Psoralen (Amotosalen HCl) and Long-Wavelength UV
WC Van Voorhis, LK Barrett, RT Eastman, R Alfonso, K Dupuis
Antimicrobial agents and chemotherapy 47 (2), 475-479, 2003
962003
Trypanosoma cruzi Inactivation in Human Platelet Concentrates and Plasma by a Psoralen (Amotosalen HCl) and Long-Wavelength UV
WC Van Voorhis, LK Barrett, RT Eastman, R Alfonso, K Dupuis
Antimicrobial agents and chemotherapy 47 (2), 475-479, 2003
962003
A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation
KK Ojo, RT Eastman, RSR Vidadala, Z Zhang, KL Rivas, R Choi, JD Lutz, ...
The Journal of infectious diseases 209 (2), 275-284, 2014
942014
Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum
RT Eastman, J White, O Hucke, K Bauer, K Yokoyama, L Nallan, ...
Journal of Biological Chemistry 280 (14), 13554-13559, 2005
862005
The Candida albicans Lanosterol 14-α-Demethylase (ERG11) Gene Promoter Is Maximally Induced after Prolonged Growth with Antifungal Drugs
JL Song, JB Harry, RT Eastman, BG Oliver, TC White
Antimicrobial agents and chemotherapy 48 (4), 1136-1144, 2004
832004
Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents
J Ohkanda, FS Buckner, JW Lockman, K Yokoyama, D Carrico, ...
Journal of medicinal chemistry 47 (2), 432-445, 2004
692004
Cloning, heterologous expression, and substrate specificities of protein farnesyltransferases from Trypanosoma cruzi and Leishmania major
FS Buckner, RT Eastman, JL Nepomuceno-Silva, EC Speelmon, PJ Myler, ...
Molecular and biochemical parasitology 122 (2), 181-188, 2002
682002
Leishmania inactivation in human pheresis platelets by a psoralen (amotosalen HCl) and long‐wavelength ultraviolet irradiation
RT Eastman, LK Barrett, K Dupuis, FS Buckner, WC Van Voorhis
Transfusion 45 (9), 1459-1463, 2005
662005
An OpenData portal to share COVID-19 drug repurposing data in real time
KR Brimacombe, T Zhao, RT Eastman, X Hu, K Wang, M Backus, ...
BioRxiv, 2020
652020
Drug repurposing screen for compounds inhibiting the cytopathic effect of SARS-CoV-2
CZ Chen, P Shinn, Z Itkin, RT Eastman, R Bostwick, L Rasmussen, ...
Frontiers in Pharmacology 11, 592737, 2021
632021
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Articles 1–20