| Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds EM Guantai, K Ncokazi, TJ Egan, J Gut, PJ Rosenthal, PJ Smith, ... Bioorganic & medicinal chemistry 18 (23), 8243-8256, 2010 | 243 | 2010 |
| Synthesis, antimalarial and antitubercular activity of acetylenic chalcones RH Hans, EM Guantai, C Lategan, PJ Smith, B Wan, SG Franzblau, J Gut, ... Bioorganic & medicinal chemistry letters 20 (3), 942-944, 2010 | 229 | 2010 |
| Enone–and chalcone–chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies EM Guantai, K Ncokazi, TJ Egan, J Gut, PJ Rosenthal, R Bhampidipati, ... Journal of medicinal chemistry 54 (10), 3637-3649, 2011 | 107 | 2011 |
| How can natural products serve as a viable source of lead compounds for the development of new/novel anti-malarials? E Guantai, K Chibale Malaria Journal 10, 1-8, 2011 | 81 | 2011 |
| Prescription patterns and adequacy of blood pressure control among adult hypertensive patients in Kenya; findings and implications JM Mbui, MN Oluka, EM Guantai, KA Sinei, L Achieng, A Baker, M Jande, ... Expert review of clinical pharmacology 10 (11), 1263-1271, 2017 | 68 | 2017 |
| Computer-aided drug discovery approaches against the tropical infectious diseases malaria, tuberculosis, trypanosomiasis, and leishmaniasis PM Njogu, EM Guantai, E Pavadai, K Chibale ACS infectious diseases 2 (1), 8-31, 2016 | 64 | 2016 |
| Effects of highly active novel artemisinin–chloroquinoline hybrid compounds on β-hematin formation, parasite morphology and endocytosis in Plasmodium falciparum TS Feng, EM Guantai, M Nell, CEJ van Rensburg, K Ncokazi, TJ Egan, ... Biochemical pharmacology 82 (3), 236-247, 2011 | 46 | 2011 |
| Examination of WHO/INRUD core drug use indicators at public primary healthcare centers in Kisii County, Kenya AO Nyabuti, FA Okalebo, EM Guantai Advances in pharmacological and pharmaceutical sciences 2020, 2020 | 30 | 2020 |
| Mangifera indica L.(anacardiaceae) S Derese, EM Guantai, Y Souaibou, V Kuete Medicinal Spices and Vegetables from Africa, 451-483, 2017 | 28 | 2017 |
| Antiplasmodial and antitumor activity of dihydroartemisinin analogs derived via the aza-Michael addition reaction TS Feng, EM Guantai, MJ Nell, CEJ van Rensburg, HC Hoppe, K Chibale Bioorganic & medicinal chemistry letters 21 (10), 2882-2886, 2011 | 28 | 2011 |
| Synthesis, biological evaluation and mechanistic studies of totarol amino alcohol derivatives as potential antimalarial agents C Tacon, EM Guantai, PJ Smith, K Chibale Bioorganic & medicinal chemistry 20 (2), 893-902, 2012 | 25 | 2012 |
| Chloroquine resistance: proposed mechanisms and countermeasures E Guantai, K Chibale Current drug delivery 7 (4), 312-323, 2010 | 20 | 2010 |
| Alkenyl cyclohexanone derivatives from Lannea rivae and Lannea schweinfurthii S Yaouba, A Koch, EM Guantai, S Derese, B Irungu, M Heydenreich, ... Phytochemistry letters 23, 141-148, 2018 | 16 | 2018 |
| Metformin's effectiveness in preventing prednisone-induced hyperglycemia in hematological cancers LA Ochola, DG Nyamu, EM Guantai, IW Weru Journal of Oncology Pharmacy Practice 26 (4), 823-834, 2020 | 12 | 2020 |
| Crystal Structures and Cytotoxicity of ent-Kaurane-Type Diterpenoids from Two Aspilia Species S Yaouba, A Valkonen, P Coghi, J Gao, EM Guantai, S Derese, ... Molecules 23 (12), 3199, 2018 | 9 | 2018 |
| Financing and Availability of Essential Medicines Before and After Introduction of the National Hospital Insurance Fund Civil Servants and Disciplined Services Medical Scheme … LW Mecca, J Riungu, EM Guantai African Journal of Pharmacology and Therapeutics 3 (4), 128-133, 2014 | 9 | 2014 |
| Natural product-based drug discovery in Africa: The need for integration into modern drug discovery paradigms EM Guantai, K Chibale Drug Discovery in Africa: Impacts of Genomics, Natural Products, Traditional …, 2012 | 8 | 2012 |
| Extracting molecular information from African natural products to facilitate unique African-led drug-discovery efforts K Chibale, EM Guantai, C Masimirembwa Future Medicinal Chemistry 3 (3), 257-261, 2011 | 7 | 2011 |
| Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2 B Laleu, K Rubiano, T Yeo, I Hallyburton, M Anderson, ... ChemMedChem 17 (22), e202200393, 2022 | 6 | 2022 |
| Replenishing the malaria drug discovery pipeline: screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum … KJ Dechering, M Timmerman, K Rensen, KMJ Koolen, S Honarnejad, ... SLAS Discovery 27 (6), 337-348, 2022 | 6 | 2022 |
Timothy J EganProfessor of Chemistry, University of Cape TownVerified email at uct.ac.za
