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Irene Weber
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Conserved folding in retroviral proteases: crystal structure of synthetic HIV-1 protease
A Wlodawer, M Miller, M Jaskolski, BK Sathyanarayana, E Baldwin, ...
Science 245 (4918), 616-621, 1989
14601989
The structure of the E. coli recA protein monomer and polymer
RM Story, IT Weber, TA Steitz
Nature 355 (6358), 318-325, 1992
9531992
Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 Ĺ resolution
IT Weber, TA Steitz
Journal of molecular biology 198 (2), 311-326, 1987
5721987
Crystal structure of interleukin 8: symbiosis of NMR and crystallography.
ET Baldwin, IT Weber, R St Charles, JC Xuan, E Appella, M Yamada, ...
Proceedings of the National Academy of Sciences 88 (2), 502-506, 1991
4951991
Model structure of decorin and implications for collagen fibrillogenesis
IT Weber, RW Harrison, RV Iozzo
Journal of Biological Chemistry 271 (50), 31767-31770, 1996
4311996
Novel bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human …
Y Koh, H Nakata, K Maeda, H Ogata, G Bilcer, T Devasamudram, ...
Antimicrobial agents and chemotherapy 47 (10), 3123-3129, 2003
4252003
Structure and function of epidermal growth factor‐like regions in proteins
E Appella, IT Weber, F Blasi
FEBS letters 231 (1), 1-4, 1988
3611988
Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families
G Velho, H Blanche, M Vaxillaire, C Bellanne-Chantelot, VC Pardini, ...
Diabetologia 40 (2), 217-224, 1997
3601997
Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus.
M Stoffel, PH Froguel, J Takeda, H Zouali, N Vionnet, S Nishi, IT Weber, ...
Proceedings of the National Academy of Sciences 89 (16), 7698-7702, 1992
2941992
Structure of catabolite gene activator protein at 2.9-A resolution. Incorporation of amino acid sequence and interactions with cyclic AMP.
DB McKay, IT Weber, TA Steitz
Journal of Biological Chemistry 257 (16), 9518-9524, 1982
2851982
Design of HIV protease inhibitors targeting protein backbone: an effective strategy for combating drug resistance
AK Ghosh, BD Chapsal, IT Weber, H Mitsuya
Accounts of chemical research 41 (1), 78-86, 2008
2692008
High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains
Y Tie, PI Boross, YF Wang, L Gaddis, AK Hussain, S Leshchenko, ...
Journal of molecular biology 338 (2), 341-352, 2004
2562004
Molecular modeling of the HIV-1 protease and its substrate binding site
IT Weber, M Miller, M Jaskólski, J Leis, AM Skalka, A Wlodawer
Science 243 (4893), 928-931, 1989
2321989
Glucokinase mutations, insulin secretion, and diabetes mellitus
GI Bell, SJ Pilkis, IT Weber, KS Polonsky
Annual Review of Physiology 58 (1), 171-186, 1996
1991996
Model of specific complex between catabolite gene activator protein and B-DNA suggested by electrostatic complementarity.
IT Weber, TA Steitz
Proceedings of the National Academy of Sciences 81 (13), 3973-3977, 1984
1961984
Predicted structures of cAMP binding domains of type I and II regulatory subunits of cAMP-dependent protein kinase
IT Weber, TA Steitz, J Bubis, SS Taylor
Biochemistry 26 (2), 343-351, 1987
1831987
The cAMP-binding domains of the regulatory subunit of cAMP-dependent protein kinase and the catabolite gene activator protein are homologous.
IT Weber, K Takio, K Titani, TA Steitz
Proceedings of the National Academy of Sciences 79 (24), 7679-7683, 1982
1761982
Geometric criteria of hydrogen bonds in proteins and identification ofbifurcated'hydrogen bonds
IY Torshin, IT Weber, RW Harrison
Protein Engineering, Design and Selection 15 (5), 359-363, 2002
1712002
Structural and kinetic analysis of drug resistant mutants of HIV‐1 protease
B Mahalingam, JM Louis, CC Reed, JM Adomat, J Krouse, YF Wang, ...
European Journal of Biochemistry 263 (1), 238-244, 1999
1641999
Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance
AK Ghosh, PR Sridhar, S Leshchenko, AK Hussain, J Li, AY Kovalevsky, ...
Journal of medicinal chemistry 49 (17), 5252-5261, 2006
1602006
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