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Zhi Tan
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Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer
JP Robichaux, YY Elamin, Z Tan, BW Carter, S Zhang, S Liu, S Li, T Chen, ...
Nature medicine 24 (5), 638-646, 2018
3212018
Epigenetic activation of WNT5A drives glioblastoma stem cell differentiation and invasive growth
B Hu, Q Wang, YA Wang, S Hua, CEG Sauvé, D Ong, ZD Lan, Q Chang, ...
Cell 167 (5), 1281-1295. e18, 2016
2022016
Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer
W Yao, JL Rose, W Wang, S Seth, H Jiang, A Taguchi, J Liu, L Yan, ...
Nature 568 (7752), 410-414, 2019
1212019
Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane FluidityMembrane Fluidity Controls Metastasis
W Zhao, S Prijic, BC Urban, MJ Tisza, Y Zuo, L Li, Z Tan, X Chen, SA Mani, ...
Cancer research 76 (7), 2037-2049, 2016
1042016
Computational polypharmacology: a new paradigm for drug discovery
R Chaudhari, Z Tan, B Huang, S Zhang
Expert opinion on drug discovery 12 (3), 279-291, 2017
802017
Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor MicroenvironmentCLOCK in Tumor Immunity
P Chen, WH Hsu, A Chang, Z Tan, Z Lan, A Zhou, DJ Spring, FF Lang, ...
Cancer discovery 10 (3), 371-381, 2020
562020
Polypharmacology in drug development: a minireview of current technologies
Z Tan, R Chaudhai, S Zhang
ChemMedChem 11 (12), 1211-1218, 2016
332016
Comprehensive modeling and discovery of mebendazole as a novel TRAF2-and NCK-interacting kinase inhibitor
Z Tan, L Chen, S Zhang
Scientific reports 6 (1), 1-10, 2016
322016
An up-to-date overview of computational polypharmacology in modern drug discovery
R Chaudhari, LW Fong, Z Tan, B Huang, S Zhang
Expert opinion on drug discovery 15 (9), 1025-1044, 2020
272020
Past, present, and future of targeting ras for cancer therapies
Z Tan, S Zhang
Mini reviews in medicinal chemistry 16 (5), 345-357, 2016
192016
Curation and analysis of multitargeting agents for polypharmacological modeling
AS Reddy, Z Tan, S Zhang
Journal of chemical information and modeling 54 (9), 2536-2543, 2014
182014
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors
S Chamakuri, S Lu, MN Ucisik, KM Bohren, YC Chen, HC Du, JC Faver, ...
Proceedings of the National Academy of Sciences 118 (36), e2111172118, 2021
172021
A noncoding RNA modulator potentiates phenylalanine metabolism in mice
Y Li, Z Tan, Y Zhang, Z Zhang, Q Hu, K Liang, Y Jun, Y Ye, YC Li, C Li, ...
Science 373 (6555), 662-673, 2021
172021
Methylation of HSP70 Orchestrates Its Binding to and Stabilization of BCL2 mRNA and Renders Pancreatic Cancer Cells Resistant to TherapeuticsProtein Methylation and PDAC …
L Wang, Z Jia, D Xie, T Zhao, Z Tan, S Zhang, F Kong, D Wei, K Xie
Cancer Research 80 (20), 4500-4513, 2020
162020
FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia
V Seda, E Vojackova, L Ondrisova, L Kostalova, S Sharma, T Loja, ...
Blood 138 (9), 758-772, 2021
152021
Interaction between nanoparticles and charged phospholipid membranes
B Huang, Z Tan, K Bohinc, S Zhang
Physical Chemistry Chemical Physics 20 (46), 29249-29263, 2018
72018
OA 12.01 the preclinical and clinical activity of poziotinib, a potent, selective inhibitor of EGFR Exon 20 mutant NSCLC
Y Elamin, J Robichaux, V Lam, A Tsao, C Lu, G Blumenschein, J Kurie, ...
Journal of Thoracic Oncology 12 (11), S1776, 2017
72017
Overview of drug polypharmacology and multitargeted molecular design
R Chaudhari, Z Tan, S Zhang
Drug Discovery Technologies, 258-275, 2017
72017
Germline and somatic smoothened mutations in non-small-cell lung cancer are potentially responsive to hedgehog inhibitor vismodegib
AS Tsao, I Wistuba, D Xia, L Byers, L Diao, J Wang, ...
JCO precision oncology 1, 1-10, 2017
52017
Trans fatty acids influence the oxidation of LDL in ECV304 cells
T Zhi, L Yanhong, L Rui, S Jian, L Jinping, W Junzhu
European Journal of Lipid Science and Technology 114 (8), 880-888, 2012
52012
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