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Matt Kelley
Matt Kelley
Verified email at pfizer.com - Homepage
Title
Cited by
Cited by
Year
Seizing control of KCC2: a new therapeutic target for epilepsy
YE Moore, MR Kelley, NJ Brandon, TZ Deeb, SJ Moss
Trends in neurosciences 40 (9), 555-571, 2017
1402017
KCC2 activity is critical in limiting the onset and severity of status epilepticus
L Silayeva, TZ Deeb, RM Hines, MR Kelley, MB Munoz, HHC Lee, ...
Proceedings of the National Academy of Sciences 112 (11), 3523-3528, 2015
1332015
Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivo
S Sivakumaran, RA Cardarelli, J Maguire, MR Kelley, L Silayeva, ...
Journal of Neuroscience 35 (21), 8291-8296, 2015
1052015
Expandable and rapidly differentiating human induced neural stem cell lines for multiple tissue engineering applications
DM Cairns, K Chwalek, YE Moore, MR Kelley, RD Abbott, S Moss, ...
Stem cell reports 7 (3), 557-570, 2016
762016
Compromising KCC2 transporter activity enhances the development of continuous seizure activity
MR Kelley, TZ Deeb, NJ Brandon, J Dunlop, PA Davies, SJ Moss
Neuropharmacology 108, 103-110, 2016
562016
Locally reducing KCC2 activity in the hippocampus is sufficient to induce temporal lobe epilepsy
MR Kelley, RA Cardarelli, JL Smalley, TA Ollerhead, PM Andrew, ...
EBioMedicine 32, 62-71, 2018
542018
Discovery of the migraine prevention therapeutic aimovig (Erenumab), the first FDA-approved antibody against a G-protein-coupled receptor
CT King, CV Gegg, SNY Hu, H Sen Lu, BM Chan, KA Berry, DW Brankow, ...
ACS Pharmacology & Translational Science 2 (6), 485-490, 2019
252019
KCC2 is required for the survival of mature neurons but not for their development
G Kontou, SFJ Ng, RA Cardarelli, JH Howden, C Choi, Q Ren, ...
Journal of Biological Chemistry 296, 2021
172021
The role of deficits in KCC2-mediated ion transport in the development and severity of temporal lobe epilepsy
M Kelley
Tufts University-Graduate School of Biomedical Sciences, 2018
2018
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