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Georgios Koukos
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Hepatic fibroblast growth factor 21 is regulated by PPARα and is a key mediator of hepatic lipid metabolism in ketotic states
MK Badman, P Pissios, AR Kennedy, G Koukos, JS Flier, E Maratos-Flier
Cell metabolism 5 (6), 426-437, 2007
17302007
MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis
G Koukos, C Polytarchou, JL Kaplan, A Morley–Fletcher, B Gras–Miralles, ...
Gastroenterology 145 (4), 842-852. e2, 2013
2572013
A matrix metalloprotease‐PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis
SL Tressel, NC Kaneider, S Kasuda, C Foley, G Koukos, K Austin, ...
EMBO molecular medicine 3 (7), 370-384, 2011
1402011
MicroRNA214 is associated with progression of ulcerative colitis, and inhibition reduces development of colitis and colitis-associated cancer in mice
C Polytarchou, DW Hommes, T Palumbo, M Hatziapostolou, ...
Gastroenterology 149 (4), 981-992. e11, 2015
1392015
HDL biogenesis, remodeling, and catabolism
VI Zannis, P Fotakis, G Koukos, D Kardassis, C Ehnholm, M Jauhiainen, ...
Handb Exp Pharmacol 224, 53-111, 2015
1362015
Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models
SL Tressel, G Koukos, B Tchernychev, SL Jacques, L Covic, A Kuliopulos
Cell-Penetrating Peptides: Methods and Protocols, 259-275, 2011
1102011
Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1
L Dowal, DS Sim, JR Dilks, P Blair, S Beaudry, BM Denker, G Koukos, ...
Proceedings of the National Academy of Sciences 108 (7), 2951-2956, 2011
842011
Protease-activated receptor-2 modulates protease-activated Receptor-1–driven neointimal hyperplasia
LM Sevigny, KM Austin, P Zhang, S Kasuda, G Koukos, S Sharifi, L Covic, ...
Arteriosclerosis, thrombosis, and vascular biology 31 (12), e100-e106, 2011
832011
Assessment of circulating microRNAs for the diagnosis and disease activity evaluation in patients with ulcerative colitis by using the nanostring technology
C Polytarchou, A Oikonomopoulos, S Mahurkar, A Touroutoglou, ...
Inflammatory bowel diseases 21 (11), 2533-2539, 2015
742015
A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium
G Koukos, C Polytarchou, JL Kaplan, A Oikonomopoulos, D Ziring, ...
Inflammatory bowel diseases 21 (5), 996-1005, 2015
652015
Noncanonical matrix metalloprotease 1–protease-activated receptor 1 signaling drives progression of atherosclerosis
R Rana, T Huang, G Koukos, EK Fletcher, SE Turner, A Shearer, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (6), 1368-1380, 2018
442018
Matrix metalloprotease 1a deficiency suppresses tumor growth and angiogenesis
CJ Foley, M Fanjul-Fernández, A Bohm, N Nguyen, A Agarwal, K Austin, ...
Oncogene 33 (17), 2264-2272, 2014
432014
Allosteric activation of a G protein-coupled receptor with cell-penetrating receptor mimetics
P Zhang, AJ Leger, JD Baleja, R Rana, T Corlin, N Nguyen, G Koukos, ...
Journal of Biological Chemistry 290 (25), 15785-15798, 2015
422015
The carboxy-terminal region of apoA-I is required for the ABCA1-dependent formation of α-HDL but not preβ-HDL particles in vivo
A Chroni, G Koukos, A Duka, VI Zannis
Biochemistry 46 (19), 5697-5708, 2007
402007
Tumor progression locus 2 mediates signal-induced increases in cytoplasmic calcium and cell migration
M Hatziapostolou, G Koukos, C Polytarchou, F Kottakis, ...
Science signaling 4 (187), ra55-ra55, 2011
392011
LCAT can Rescue the Abnormal Phenotype Produced by the Natural ApoA-I Mutations (Leu141Arg)Pisa and (Leu159Arg)FIN
G Koukos, A Chroni, A Duka, D Kardassis, VI Zannis
Biochemistry 46 (37), 10713-10721, 2007
392007
Apolipoprotein L1-specific antibodies detect endogenous APOL1 inside the endoplasmic reticulum and on the plasma membrane of podocytes
SJ Scales, N Gupta, AM De Mazičre, G Posthuma, CP Chiu, AA Pierce, ...
Journal of the American Society of Nephrology 31 (9), 2044-2064, 2020
362020
Naturally occurring and bioengineered apoA-I mutations that inhibit the conversion of discoidal to spherical HDL: the abnormal HDL phenotypes can be corrected by treatment with …
G Koukos, A Chroni, A Duka, D Kardassis, VI Zannis
Biochemical Journal 406 (1), 167-174, 2007
362007
Systems biology in inflammatory bowel diseases: ready for prime time
C Polytarchou, G Koukos, D Iliopoulos
Current opinion in gastroenterology 30 (4), 339-346, 2014
342014
Discrete roles of apoA‐I and apoE in the biogenesis of HDL species: lessons learned from gene transfer studies in different mouse models
VI Zannis, G Koukos, K Drosatos, A Vezeridis, EE Zanni, KE Kypreos, ...
Annals of medicine 40 (sup1), 14-28, 2008
342008
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Articles 1–20