Jeanette Leusen
Jeanette Leusen
associate prof Immunotherapie, UMC Utrecht
Verified email at - Homepage
Cited by
Cited by
Mechanisms of action of CD20 antibodies
P Boross, JHW Leusen
American journal of cancer research 2 (6), 676, 2012
Glycoengineered CD20 antibody obinutuzumab activates neutrophils and mediates phagocytosis through CD16B more efficiently than rituximab
J Golay, F Da Roit, L Bologna, C Ferrara, JH Leusen, A Rambaldi, C Klein, ...
Blood, The Journal of the American Society of Hematology 122 (20), 3482-3491, 2013
The therapeutic CD38 monoclonal antibody daratumumab induces programmed cell death via Fcγ receptor–mediated cross-linking
MB Overdijk, JH Jansen, M Nederend, JJ Lammerts van Bueren, ...
The Journal of Immunology 197 (3), 807-813, 2016
Mac-1 (CD11b/CD18) is essential for Fc receptor–mediated neutrophil cytotoxicity and immunologic synapse formation
AB van Spriel, JHW Leusen, M van Egmond, HBPM Dijkman, ...
Blood, The Journal of the American Society of Hematology 97 (8), 2478-2486, 2001
Neutrophils kill antibody-opsonized cancer cells by trogoptosis
HL Matlung, L Babes, XW Zhao, M van Houdt, LW Treffers, DJ van Rees, ...
Cell Reports 23 (13), 3946-3959. e6, 2018
Crosstalk between human IgG isotypes and murine effector cells
MB Overdijk, S Verploegen, A Ortiz Buijsse, T Vink, JHW Leusen, ...
The Journal of Immunology 189 (7), 3430-3438, 2012
Functional characteristics of the high affinity IgG receptor, FcγRI
CE van der Poel, RM Spaapen, JGJ van de Winkel, JHW Leusen
The Journal of Immunology 186 (5), 2699-2704, 2011
Interactions between the components of the human NADPH oxidase: intrigues in the phox family
JHW Leusen, AJ Verhoeven, D Roos
Journal of Laboratory and Clinical Medicine 128 (5), 461-476, 1996
In vivo cytotoxicity of type I CD20 antibodies critically depends on Fc receptor ITAM signaling
S de Haij, JHM Jansen, P Boross, FJ Beurskens, JE Bakema, DL Bos, ...
Cancer research 70 (8), 3209-3217, 2010
156Pro--> Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox andá…
JH Leusen, BG Bolscher, PM Hilarius, RS Weening, W Kaulfersch, ...
The Journal of experimental medicine 180 (6), 2329-2334, 1994
The high-affinity IgG receptor, FcγRI, plays a central role in antibody therapy of experimental melanoma
L Bevaart, MJH Jansen, MJ van Vugt, JS Verbeek, JGJ van de Winkel, ...
Cancer research 66 (3), 1261-1264, 2006
A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox.
JH Leusen, M De Boer, BG Bolscher, PM Hilarius, RS Weening, HD Ochs, ...
The Journal of clinical investigation 93 (5), 2120-2126, 1994
Effects of bovine immunoglobulins on immune function, allergy, and infection
LH Ulfman, JHW Leusen, HFJ Savelkoul, JO Warner, RJJ Van Neerven
Frontiers in nutrition 5, 52, 2018
Prevalence, genetics and clinical presentation of chronic granulomatous disease in Sweden
A ┼hlin, M De Boer, D Roos, J Leusen, CIE Smith, U Sundin, H Rabbani, ...
Acta paediatrica 84 (12), 1386-1394, 1995
Glutaminyl cyclase is an enzymatic modifier of the CD47-SIRPα axis and a target for cancer immunotherapy
MEW Logtenberg, JHM Jansen, M Raaben, M Toebes, K Franke, ...
Nature medicine 25 (4), 612-619, 2019
The importance of human FcγRI in mediating protection to malaria
RS McIntosh, J Shi, RM Jennings, JC Chappel, TF de Koning-Ward, ...
PLoS pathogens 3 (5), e72, 2007
IgA EGFR antibodies mediate tumour killing in vivo
P Boross, S Lohse, M Nederend, JHM Jansen, G van Tetering, M Dechant, ...
EMBO molecular medicine 5 (8), 1213-1226, 2013
Targeted delivery of a sialic acid-blocking glycomimetic to cancer cells inhibits metastatic spread
C Bull, TJ Boltje, EAW van Dinther, T Peters, AMA de Graaf, JHW Leusen, ...
ACS nano 9 (1), 733-745, 2015
Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous disease.
JH Leusen, A de Klein, PM Hilarius, A Ahlin, J Palmblad, CI Smith, ...
The Journal of experimental medicine 184 (4), 1243-1249, 1996
Plant-derived anti-Lewis Y mAb exhibits biological activities for efficient immunotherapy against human cancer cells
R Brodzik, M Glogowska, K Bandurska, M Okulicz, D Deka, K Ko, ...
Proceedings of the National Academy of Sciences 103 (23), 8804-8809, 2006
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