Paul Murphy
Paul Murphy
University of Galway Professor of Chemistry
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Multivalent glycoconjugates as anti-pathogenic agents
A Bernardi, J Jiménez-Barbero, A Casnati, C De Castro, T Darbre, ...
Chemical Society Reviews 42 (11), 4709-4727, 2013
SnCl4- and TiCl4-Catalyzed Anomerization of Acylated O- and S-Glycosides: Analysis of Factors That Lead to Higher α:β Anomer Ratios and Reaction Rates
W Pilgrim, PV Murphy
The Journal of organic chemistry 75 (20), 6747-6755, 2010
Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activity
MD Swanson, DM Boudreaux, L Salmon, J Chugh, HC Winter, ...
Cell 163 (3), 746-758, 2015
Lectins: getting familiar with translators of the sugar code
S André, H Kaltner, JC Manning, PV Murphy, HJ Gabius
Molecules 20 (2), 1788-1823, 2015
Synthesis of α-glucuronic acid and amide derivatives in the presence of a participating 2-acyl protecting group
M Tosin, PV Murphy
Organic Letters 4 (21), 3675-3678, 2002
Conformational effects on glycoside reactivity: Study of the high reactive conformer of glucose
C McDonnell, O López, P Murphy, JG Fernández Bolańos, R Hazell, ...
Journal of the American Chemical Society 126 (39), 12374-12385, 2004
New Access to 1-Deoxynojirimycin Derivatives via Azide− Alkene Cycloaddition
Y Zhou, PV Murphy
Organic letters 10 (17), 3777-3780, 2008
A Ramberg-Bäcklund approach to exo-glycals
FK Griffin, PV Murphy, DE Paterson, RJK Taylor
Tetrahedron letters 39 (44), 8179-8182, 1998
A general synthesis of iminosugars
C McDonnell, L Cronin, JL O'Brie, PV Murphy
The Journal of Organic Chemistry 69 (10), 3565-3568, 2004
Multivalent carbohydrate-lectin interactions: How synthetic chemistry enables insights into nanometric recognition
R Roy, PV Murphy, HJ Gabius
Molecules 21 (5), 629, 2016
The third dimension of reading the sugar code by lectins: design of glycoclusters with cyclic scaffolds as tools with the aim to define correlations between spatial …
PV Murphy, S André, HJ Gabius
Molecules 18 (4), 4026-4053, 2013
Development of Mcl-1 inhibitors for cancer therapy
A Negi, PV Murphy
European journal of medicinal chemistry 210, 113038, 2021
Synthesis of novel HIV-1 protease inhibitors based on carbohydrate scaffolds
PV Murphy, JL O'Brien, LJ Gorey-Feret, AB Smith III
Tetrahedron 59 (13), 2259-2271, 2003
Glycosidation Reactions of Silyl Ethers with Conformationally Inverted Donors Derived from Glucuronic Acid: Stereoselective Synthesis of Glycosides and 2‐Deoxyglycosides
M Poláková, N Pitt, M Tosin, PV Murphy
Angewandte Chemie 116 (19), 2572-2575, 2004
Synthesis of Bivalent Lactosides Based on Terephthalamide, N,N′-Diglucosylterephthalamide, and Glycophane Scaffolds and Assessment of Their Inhibitory …
R Leyden, T Velasco-Torrijos, S Andre, S Gouin, HJ Gabius, PV Murphy
The Journal of Organic Chemistry 74 (23), 9010-9026, 2009
Application of Ugi reactions in synthesis of divalent neoglycoconjugates: Evidence that the sugars are presented in restricted conformation
H Bradley, G Fitzpatrick, WK Glass, H Kunz, PV Murphy
Organic Letters 3 (17), 2629-2632, 2001
Hybrid angiogenesis inhibitors: synthesis and biological evaluation of bifunctional compounds based on 1-deoxynojirimycin and aryl-1, 2, 3-triazoles
Y Zhou, Y Zhao, KM O’Boyle, PV Murphy
Bioorganic & medicinal chemistry letters 18 (3), 954-958, 2008
Glycosidation–Anomerisation Reactions of 6,1‐Anhydroglucopyranuronic Acid and Anomerisation of β‐D‐Glucopyranosiduronic Acids Promoted by SnCl4
C O'Brien, M Poláková, N Pitt, M Tosin, PV Murphy
Chemistry–A European Journal 13 (3), 902-909, 2007
Novel synthesis of castanospermine and 1-epicastanospermine
L Cronin, PV Murphy
Organic Letters 7 (13), 2691-2693, 2005
α-Glycosphingolipids via Chelation-Induced Anomerization of O- and S-Glucuronic and Galacturonic Acid Derivatives
W Pilgrim, PV Murphy
Organic Letters 11 (4), 939-942, 2009
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