L. Renee Ruhaak
L. Renee Ruhaak
Assistant Professor at Leiden University Medical Center
Verified email at
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Cited by
Glycan labeling strategies and their use in identification and quantification
LR Ruhaak, G Zauner, C Huhn, C Bruggink, AM Deelder, M Wuhrer
Analytical and bioanalytical chemistry 397, 3457-3481, 2010
Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: a critical review
E Maverakis, K Kim, M Shimoda, ME Gershwin, F Patel, R Wilken, ...
Journal of autoimmunity 57, 1-13, 2015
Oligosaccharide analysis by mass spectrometry: a review of recent developments
MJ Kailemia, LR Ruhaak, CB Lebrilla, IJ Amster
Analytical chemistry 86 (1), 196-212, 2014
Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers
G Lauc, JE Huffman, M Pučić, L Zgaga, B Adamczyk, A Mužinić, ...
PLoS genetics 9 (1), e1003225, 2013
IgG glycosylation analysis
C Huhn, MHJ Selman, LR Ruhaak, AM Deelder, M Wuhrer
Proteomics 9 (4), 882-913, 2009
Mass spectrometry approaches to glycomic and glycoproteomic analyses
LR Ruhaak, G Xu, Q Li, E Goonatilleke, CB Lebrilla
Chemical reviews 118 (17), 7886-7930, 2018
Evaluation of a vaporizing device (VolcanoŽ) for the pulmonary administration of tetrahydrocannabinol
A Hazekamp, R Ruhaak, L Zuurman, J Van Gerven, R Verpoorte
Journal of pharmaceutical sciences 95 (6), 1308-1317, 2006
Hydrophilic interaction chromatography-based high-throughput sample preparation method for N-glycan analysis from total human plasma glycoproteins
LR Ruhaak, C Huhn, WJ Waterreus, AR De Boer, C Neusüss, CH Hokke, ...
Analytical chemistry 80 (15), 6119-6126, 2008
Oligosaccharide analysis by graphitized carbon liquid chromatography–mass spectrometry
LR Ruhaak, AM Deelder, M Wuhrer
Analytical and bioanalytical chemistry 394, 163-174, 2009
2‐Picoline‐borane: A non‐toxic reducing agent for oligosaccharide labeling by reductive amination
LR Ruhaak, E Steenvoorden, CAM Koeleman, AM Deelder, M Wuhrer
Proteomics 10 (12), 2330-2336, 2010
Comprehensive profiles of human milk oligosaccharides yield highly sensitive and specific markers for determining secretor status in lactating mothers
SM Totten, AM Zivkovic, S Wu, UT Ngyuen, SL Freeman, LR Ruhaak, ...
Journal of proteome research 11 (12), 6124-6133, 2012
Developments in the identification of glycan biomarkers for the detection of cancer
LR Ruhaak, S Miyamoto, CB Lebrilla
Molecular & Cellular Proteomics 12 (4), 846-855, 2013
Optimized workflow for preparation of APTS-labeled N-glycans allowing high-throughput analysis of human plasma glycomes using 48-channel multiplexed CGE-LIF
LR Ruhaak, R Hennig, C Huhn, M Borowiak, RJEM Dolhain, AM Deelder, ...
Journal of proteome research 9 (12), 6655-6664, 2010
Glycosylation of human milk lactoferrin exhibits dynamic changes during early lactation enhancing its role in pathogenic bacteria-host interactions
M Barboza, J Pinzon, S Wickramasinghe, JW Froehlich, I Moeller, ...
Molecular & Cellular Proteomics 11 (6), 2012
Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa
LR Ruhaak, J Felth, PC Karlsson, JJ Rafter, R Verpoorte, L Bohlin
Biological and Pharmaceutical Bulletin 34 (5), 774-778, 2011
Immunoglobulin G glycopeptide profiling by matrix-assisted laser desorption ionization Fourier transform ion cyclotron resonance mass spectrometry
MHJ Selman, LA McDonnell, M Palmblad, LR Ruhaak, AM Deelder, ...
Analytical chemistry 82 (3), 1073-1081, 2010
Decreased levels of bisecting GlcNAc glycoforms of IgG are associated with human longevity
LR Ruhaak, HW Uh, M Beekman, CAM Koeleman, CH Hokke, ...
PloS one 5 (9), e12566, 2010
Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health
R Plomp, LR Ruhaak, HW Uh, KR Reiding, M Selman, ...
Scientific reports 7 (1), 12325, 2017
Absolute quantitation of immunoglobulin G and its glycoforms using multiple reaction monitoring
Q Hong, CB Lebrilla, S Miyamoto, LR Ruhaak
Analytical chemistry 85 (18), 8585-8593, 2013
Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health
LR Ruhaak, HW Uh, M Beekman, CH Hokke, RGJ Westendorp, ...
Journal of proteome research 10 (4), 1667-1674, 2011
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