Mario Losen
Mario Losen
assistant professor, Maastricht University
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Cited by
Cited by
Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange
M Van Der Neut Kolfschoten, J Schuurman, M Losen, WK Bleeker, ...
Science 317 (5844), 1554-1557, 2007
A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis
P Zisimopoulou, P Evangelakou, J Tzartos, K Lazaridis, V Zouvelou, ...
Journal of autoimmunity 52, 139-145, 2014
MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4
MG Huijbers, W Zhang, R Klooster, EH Niks, MB Friese, KR Straasheijm, ...
Proceedings of the National Academy of Sciences 110 (51), 20783-20788, 2013
Effect of Oxygen Limitation and Medium Composition on Escherichia coli Fermentation in Shake‐Flask Cultures
M Losen, B Frölich, M Pohl, J Büchs
Biotechnology progress 20 (4), 1062-1068, 2004
Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice
R Klooster, JJ Plomp, MG Huijbers, EH Niks, KR Straasheijm, FJ Detmers, ...
Brain 135 (4), 1081-1101, 2012
The features of myasthenia gravis with autoantibodies to MuSK
D Lavrnic, M Losen, A Vujic, M De Baets, LJ Hajdukovic, V Stojanovic, ...
Journal of Neurology, Neurosurgery & Psychiatry 76 (8), 1099-1102, 2005
The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria
M Bosma, R Minnaard, LM Sparks, G Schaart, M Losen, MH De Baets, ...
Histochemistry and cell biology 137, 205-216, 2012
Pathophysiology of myasthenia gravis with antibodies to the acetylcholine receptor, muscle-specific kinase and low-density lipoprotein receptor-related protein 4
JJGM Verschuuren, MG Huijbers, JJ Plomp, EH Niks, PC Molenaar, ...
Autoimmunity reviews 12 (9), 918-923, 2013
Advances in understanding and modeling the gas–liquid mass transfer in shake flasks
U Maier, M Losen, J Büchs
Biochemical Engineering Journal 17 (3), 155-167, 2004
Antibody effector mechanisms in myasthenia gravis—pathogenesis at the neuromuscular junction
AM Gomez, J Van Den Broeck, K Vrolix, SP Janssen, MAM Lemmens, ...
Autoimmunity 43 (5-6), 353-370, 2010
Proteasome inhibition with bortezomib depletes plasma cells and autoantibodies in experimental autoimmune myasthenia gravis
AM Gomez, K Vrolix, P Martínez-Martínez, PC Molenaar, M Phernambucq, ...
The Journal of Immunology 186 (4), 2503-2513, 2011
IgG4 autoantibodies against muscle-specific kinase undergo Fab-arm exchange in myasthenia gravis patients
I Koneczny, JAA Stevens, A De Rosa, S Huda, MG Huijbers, A Saxena, ...
Journal of autoimmunity 77, 104-115, 2017
Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and …
J Luo, P Taylor, M Losen, MH de Baets, GD Shelton, J Lindstrom
Journal of Neuroscience 29 (44), 13898-13908, 2009
Muscle disuse atrophy is not accompanied by changes in skeletal muscle satellite cell content
T Snijders, BT Wall, ML Dirks, JMG Senden, F Hartgens, J Dolmans, ...
Clinical science 126 (8), 557-566, 2014
In vivo electroporation of the central nervous system: a non-viral approach for targeted gene delivery
J De Vry, P Martínez-Martínez, M Losen, Y Temel, T Steckler, ...
Progress in neurobiology 92 (3), 227-244, 2010
Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis
M Losen, MHW Stassen, P Martínez-Martínez, BM Machiels, H Duimel, ...
Brain 128 (10), 2327-2337, 2005
MuSK autoantibodies in myasthenia gravis detected by cell based assay—a multinational study
AI Tsonis, P Zisimopoulou, K Lazaridis, J Tzartos, E Matsigkou, ...
Journal of neuroimmunology 284, 10-17, 2015
The auto-antigen repertoire in myasthenia gravis
K Vrolix, J Fraussen, PC Molenaar, M Losen, V Somers, P Stinissen, ...
Autoimmunity 43 (5-6), 380-400, 2010
IL‐17‐producing CD4+ T cells contribute to the loss of B‐cell tolerance in experimental autoimmune myasthenia gravis
H Schaffert, A Pelz, A Saxena, M Losen, A Meisel, A Thiel, S Kohler
European journal of immunology 45 (5), 1339-1347, 2015
Titin antibodies in “seronegative” myasthenia gravis—a new role for an old antigen
C Stergiou, K Lazaridis, V Zouvelou, J Tzartos, R Mantegazza, C Antozzi, ...
Journal of neuroimmunology 292, 108-115, 2016
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