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Maria Laura Bolognesi
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Multi-target-directed ligands to combat neurodegenerative diseases
A Cavalli, ML Bolognesi, A Minarini, M Rosini, V Tumiatti, M Recanatini, ...
Journal of medicinal chemistry 51 (3), 347-372, 2008
12742008
A perspective on multi-target drug discovery and design for complex diseases
RR Ramsay, MR Popovic-Nikolic, K Nikolic, E Uliassi, ML Bolognesi
Clinical and translational medicine 7, 1-14, 2018
5892018
Insight Into the Kinetic of Amyloid β (1–42) Peptide Self‐Aggregation: Elucidation of Inhibitors’ Mechanism of Action
M Bartolini, C Bertucci, ML Bolognesi, A Cavalli, C Melchiorre, ...
ChemBioChem 8 (17), 2152-2161, 2007
4202007
Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer’s disease
ML Bolognesi, A Cavalli, L Valgimigli, M Bartolini, M Rosini, V Andrisano, ...
Journal of medicinal chemistry 50 (26), 6446-6449, 2007
3132007
Rational approach to discover multipotent anti-Alzheimer drugs
M Rosini, V Andrisano, M Bartolini, ML Bolognesi, P Hrelia, A Minarini, ...
Journal of medicinal chemistry 48 (2), 360-363, 2005
2922005
Neglected Tropical Diseases: Multi-Target-Directed Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania
A Cavalli, ML Bolognesi
Journal of Medicinal Chemistry 52 (23), 7339-7359, 2009
2772009
Tacrine derivatives and Alzheimer's disease
V Tumiatti, A Minarini, ML Bolognesi, A Milelli, M Rosini, C Melchiorre
Current medicinal chemistry 17 (17), 1825-1838, 2010
2702010
Inhibition of acetylcholinesterase, β-amyloid aggregation, and NMDA receptors in Alzheimer’s disease: a promising direction for the multi-target-directed ligands gold rush
M Rosini, E Simoni, M Bartolini, A Cavalli, L Ceccarini, N Pascu, ...
Journal of medicinal chemistry 51 (15), 4381-4384, 2008
2392008
A small molecule targeting the multifactorial nature of Alzheimer's disease
A Cavalli, ML Bolognesi, S Capsoni, V Andrisano, M Bartolini, E Margotti, ...
ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 46, 3689-3692, 2007
2352007
Molecular hybridization as a tool for designing multitarget drug candidates for complex diseases
V Ivasiv, C Albertini, AE Gonçalves, M Rossi, ML Bolognesi
Current Topics in Medicinal Chemistry 19 (19), 1694-1711, 2019
2172019
Multitarget drug discovery and polypharmacology
ML Bolognesi, A Cavalli
ChemMedChem 11 (12), 1190-1192, 2016
2162016
Multitarget drug design strategy: quinone–tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects
E Nepovimova, E Uliassi, J Korabecny, LE Pena-Altamira, S Samez, ...
Journal of medicinal chemistry 57 (20), 8576-8589, 2014
1872014
Imaging of β-amyloid plaques by near infrared fluorescent tracers: a new frontier for chemical neuroscience
M Staderini, MA Martín, ML Bolognesi, JC Menéndez
Chemical Society Reviews 44 (7), 1807-1819, 2015
1822015
Alzheimer's disease: new approaches to drug discovery
ML Bolognesi, R Matera, A Minarini, M Rosini, C Melchiorre
Current opinion in chemical biology 13 (3), 303-308, 2009
1732009
Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer’s disease
ML Bolognesi, A Cavalli, C Melchiorre
Neurotherapeutics 6, 152-162, 2009
1722009
Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease
ML Bolognesi, R Banzi, M Bartolini, A Cavalli, A Tarozzi, V Andrisano, ...
Journal of medicinal chemistry 50 (20), 4882-4897, 2007
1722007
The Hippo pathway and YAP/TAZ–TEAD protein–protein interaction as targets for regenerative medicine and cancer treatment: Miniperspective
M Santucci, T Vignudelli, S Ferrari, M Mor, L Scalvini, ML Bolognesi, ...
Journal of medicinal chemistry 58 (12), 4857-4873, 2015
1702015
Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-β aggregation
ML Bolognesi, V Andrisano, M Bartolini, R Banzi, C Melchiorre
Journal of medicinal chemistry 48 (1), 24-27, 2005
1662005
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues
ML Bolognesi, M Bartolini, A Cavalli, V Andrisano, M Rosini, A Minarini, ...
Journal of medicinal chemistry 47 (24), 5945-5952, 2004
1612004
Multitarget drug discovery for Alzheimer's disease: triazinones as BACE‐1 and GSK‐3β inhibitors
F Prati, A De Simone, P Bisignano, A Armirotti, M Summa, D Pizzirani, ...
Angewandte Chemie 127 (5), 1598-1602, 2015
1502015
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