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Wei Zheng
Wei Zheng
National Center for Advancing Translational Sciences, National Institutes of Health
Verified email at mail.nih.gov - Homepage
Title
Cited by
Cited by
Year
Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries
J Inglese, DS Auld, A Jadhav, RL Johnson, A Simeonov, A Yasgar, ...
Proceedings of the National Academy of Sciences 103 (31), 11473-11478, 2006
8292006
High-throughput screening assays for the identification of chemical probes
J Inglese, RL Johnson, A Simeonov, M Xia, W Zheng, CP Austin, DS Auld
Nature chemical biology 3 (8), 466-479, 2007
7002007
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ...
Nature medicine 22 (10), 1101-1107, 2016
5872016
Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays
K Solly, X Wang, X Xu, B Strulovici, W Zheng
Assay and drug development technologies 2 (4), 363-372, 2004
4622004
Phenotypic screens as a renewed approach for drug discovery
W Zheng, N Thorne, JC McKew
Drug discovery today 18 (21-22), 1067-1073, 2013
4442013
Inhibition of the mitochondrial protease ClpP as a therapeutic strategy for human acute myeloid leukemia
A Cole, Z Wang, E Coyaud, V Voisin, M Gronda, Y Jitkova, R Mattson, ...
Cancer cell 27 (6), 864-876, 2015
2742015
Drug combination therapy increases successful drug repositioning
W Sun, PE Sanderson, W Zheng
Drug discovery today 21 (7), 1189-1195, 2016
2532016
Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs
J Kouznetsova, W Sun, C Martínez-Romero, G Tawa, P Shinn, CZ Chen, ...
Emerging microbes & infections 3 (1), 1-7, 2014
2472014
Increased expression of the cardiac L-type calcium channel in estrogen receptor–deficient mice
BD Johnson, W Zheng, KS Korach, T Scheuer, WA Catterall, GM Rubanyi
The Journal of general physiology 110 (2), 135-140, 1997
2301997
Epitranscriptomic m6A regulation of axon regeneration in the adult mammalian nervous system
YL Weng, X Wang, R An, J Cassin, C Vissers, Y Liu, Y Liu, T Xu, X Wang, ...
Neuron 97 (2), 313-325. e6, 2018
2292018
Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor
J Hesselgesser, HP Ng, M Liang, W Zheng, K May, JG Bauman, ...
Journal of Biological Chemistry 273 (25), 15687-15692, 1998
2251998
Human pluripotent stem cell-derived neural cells and brain organoids reveal SARS-CoV-2 neurotropism predominates in choroid plexus epithelium
F Jacob, SR Pather, WK Huang, F Zhang, SZH Wong, H Zhou, B Cubitt, ...
Cell stem cell 27 (6), 937-950. e9, 2020
2202020
A new glucocerebrosidase chaperone reduces α-synuclein and glycolipid levels in iPSC-derived dopaminergic neurons from patients with Gaucher disease and parkinsonism
E Aflaki, DK Borger, N Moaven, BK Stubblefield, SA Rogers, S Patnaik, ...
Journal of Neuroscience 36 (28), 7441-7452, 2016
1962016
Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease
W Zheng, J Padia, DJ Urban, A Jadhav, O Goker-Alpan, A Simeonov, ...
Proceedings of the National Academy of Sciences 104 (32), 13192-13197, 2007
1652007
High throughput assay technologies for ion channel drug discovery
W Zheng, RH Spencer, L Kiss
Assay and drug development technologies 2 (5), 543-552, 2004
1652004
Elabela-apelin receptor signaling pathway is functional in mammalian systems
Z Wang, D Yu, M Wang, Q Wang, J Kouznetsova, R Yang, K Qian, W Wu, ...
Scientific reports 5 (1), 1-8, 2015
1632015
A robotic platform for quantitative high-throughput screening
S Michael, D Auld, C Klumpp, A Jadhav, W Zheng, N Thorne, CP Austin, ...
Assay and drug development technologies 6 (5), 637-657, 2008
1622008
Drug repurposing screens and synergistic drug‐combinations for infectious diseases
W Zheng, W Sun, A Simeonov
British journal of pharmacology 175 (2), 181-191, 2018
1592018
Molecular signatures associated with ZIKV exposure in human cortical neural progenitors
F Zhang, C Hammack, SC Ogden, Y Cheng, EM Lee, Z Wen, X Qian, ...
Nucleic acids research 44 (18), 8610-8620, 2016
1562016
Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro
Q Zhang, CZ Chen, M Swaroop, M Xu, L Wang, J Lee, AQ Wang, ...
Cell discovery 6 (1), 1-14, 2020
1482020
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