Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation K Moran-Crusio, L Reavie, A Shih, O Abdel-Wahab, D Ndiaye-Lobry, ... Cancer cell 20 (1), 11-24, 2011 | 1430 | 2011 |
SRSF2 mutations contribute to myelodysplasia by mutant-specific effects on exon recognition E Kim, JO Ilagan, Y Liang, GM Daubner, SCW Lee, A Ramakrishnan, Y Li, ... Cancer cell 27 (5), 617-630, 2015 | 598 | 2015 |
Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think C Lobry, P Oh, I Aifantis Journal of Experimental Medicine 208 (10), 1931-1935, 2011 | 429 | 2011 |
A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia A Klinakis, C Lobry, O Abdel-Wahab, P Oh, H Haeno, S Buonamici, ... Nature 473 (7346), 230-233, 2011 | 426 | 2011 |
Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins SCW Lee, H Dvinge, E Kim, H Cho, JB Micol, YR Chung, BH Durham, ... Nature medicine 22 (6), 672-678, 2016 | 358 | 2016 |
Notch signaling: switching an oncogene to a tumor suppressor C Lobry, P Oh, MR Mansour, AT Look, I Aifantis Blood, The Journal of the American Society of Hematology 123 (16), 2451-2459, 2014 | 293 | 2014 |
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells CS Guy, KM Vignali, J Temirov, ML Bettini, AE Overacre, M Smeltzer, ... Nature immunology 14 (3), 262-270, 2013 | 257 | 2013 |
T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling K Germar, M Dose, T Konstantinou, J Zhang, H Wang, C Lobry, KL Arnett, ... Proceedings of the National Academy of Sciences 108 (50), 20060-20065, 2011 | 235 | 2011 |
TET1 is a tumor suppressor of hematopoietic malignancy L Cimmino, MM Dawlaty, D Ndiaye-Lobry, YS Yap, S Bakogianni, Y Yu, ... Nature immunology 16 (6), 653-662, 2015 | 225 | 2015 |
Notch pathway activation targets AML-initiating cell homeostasis and differentiation C Lobry, P Ntziachristos, D Ndiaye-Lobry, P Oh, L Cimmino, N Zhu, ... Journal of Experimental Medicine 210 (2), 301-319, 2013 | 189 | 2013 |
PHF6 mutations in adult acute myeloid leukemia P Van Vlierberghe, J Patel, O Abdel-Wahab, C Lobry, CV Hedvat, ... Leukemia 25 (1), 130-134, 2011 | 182 | 2011 |
Negative feedback loop in T cell activation through IκB kinase-induced phosphorylation and degradation of Bcl10 C Lobry, T Lopez, A Israël, R Weil Proceedings of the National Academy of Sciences 104 (3), 908-913, 2007 | 125 | 2007 |
Tumour spheres with inverted polarity drive the formation of peritoneal metastases in patients with hypermethylated colorectal carcinomas O Zajac, J Raingeaud, F Libanje, C Lefebvre, D Sabino, I Martins, P Roy, ... Nature cell biology 20 (3), 296-306, 2018 | 108 | 2018 |
In vivo mapping of notch pathway activity in normal and stress hematopoiesis P Oh, C Lobry, J Gao, A Tikhonova, E Loizou, J Manent, B Van Handel, ... Cell stem cell 13 (2), 190-204, 2013 | 93 | 2013 |
ETO2-GLIS2 hijacks transcriptional complexes to drive cellular identity and self-renewal in pediatric acute megakaryoblastic leukemia C Thirant, C Ignacimouttou, CK Lopez, L Le Mouël, C Thiollier, A Siret, ... Cancer cell 31 (3), 452-465, 2017 | 75 | 2017 |
STAT3 supports experimental K-RasG12D–induced murine myeloproliferative neoplasms dependent on serine phosphorylation DJ Gough, IJ Marié, C Lobry, I Aifantis, DE Levy Blood, The Journal of the American Society of Hematology 124 (14), 2252-2261, 2014 | 65 | 2014 |
Dll4–Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice F Billiard, C Lobry, G Darrasse-Jèze, J Waite, X Liu, H Mouquet, ... Journal of Experimental Medicine 209 (5), 1011-1028, 2012 | 54 | 2012 |
BCL6 antagonizes NOTCH2 to maintain survival of human follicular lymphoma cells E Valls, C Lobry, H Geng, L Wang, M Cardenas, M Rivas, L Cerchietti, ... Cancer discovery 7 (5), 506-521, 2017 | 52 | 2017 |
Active and inactive enhancers cooperate to exert localized and long-range control of gene regulation C Proudhon, V Snetkova, R Raviram, C Lobry, S Badri, T Jiang, B Hao, ... Cell reports 15 (10), 2159-2169, 2016 | 48 | 2016 |
Ontogenic changes in hematopoietic hierarchy determine pediatric specificity and disease phenotype in fusion oncogene–driven myeloid leukemia CK Lopez, E Noguera, V Stavropoulou, E Robert, Z Aid, P Ballerini, ... Cancer discovery 9 (12), 1736-1753, 2019 | 42 | 2019 |