Synthesis and anti-hepatitis B virus activity of novel benzimidazole derivatives YF Li, GF Wang, PL He, WG Huang, FH Zhu, HY Gao, W Tang, Y Luo, ... Journal of medicinal chemistry 49 (15), 4790-4794, 2006 | 206 | 2006 |
Synthesis and biological evaluation of (±)-cryptotanshinone and its simplified analogues as potent CDC25 inhibitors WG Huang, YY Jiang, Q Li, J Li, JY Li, W Lu, JC Cai Tetrahedron 61 (7), 1863-1870, 2005 | 64 | 2005 |
Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations N Hajicek, NC Keith, E Siraliev-Perez, BRS Temple, W Huang, Q Zhang, ... Elife 8, e51700, 2019 | 63 | 2019 |
Identification of 1-isopropylsulfonyl-2-amine benzimidazoles as a new class of inhibitors of hepatitis B virus YF Li, GF Wang, Y Luo, WG Huang, W Tang, CL Feng, LP Shi, YD Ren, ... European journal of medicinal chemistry 42 (11-12), 1358-1364, 2007 | 58 | 2007 |
Small Molecule Inhibitors of Phospholipase C from a Novel High-throughput Screen W Huang, M Barrett, N Hajicek, S Hicks, TK Harden, J Sondek, Q Zhang Journal of Biological Chemistry, 2013 | 46 | 2013 |
Membrane-induced allosteric control of phospholipase C-β isozymes TH Charpentier, GL Waldo, MO Barrett, W Huang, Q Zhang, TK Harden, ... Journal of Biological Chemistry 289 (43), 29545-29557, 2014 | 38 | 2014 |
Synthesis of miltirone analogues as inhibitors of Cdc25 phosphatases W Huang, J Li, W Zhang, Y Zhou, C Xie, Y Luo, Y Li, J Wang, J Li, W Lu Bioorganic & medicinal chemistry letters 16 (7), 1905-1908, 2006 | 35 | 2006 |
A Fluorogenic, Small Molecule Reporter for Mammalian Phospholipase C Isozymes W Huang, SN Hicks, JE Sondek, Q Zhang ACS Chemical Biology, 2010 | 34 | 2010 |
Kinetic analysis of PI3K reactions with fluorescent PIP 2 derivatives W Huang, D Jiang, X Wang, K Wang, CE Sims, NL Allbritton, Q Zhang Analytical and Bioanalytical Chemistry, 1-8, 2011 | 31 | 2011 |
Copper-free Sonogashira reaction using 7-chloro camptothecins Y Luo, H Gao, Y Li, W Huang, W Lu, Z Zhang Tetrahedron 62 (11), 2465-2470, 2006 | 30 | 2006 |
Total synthesis of mallotophilippen C Y Li, Y Luo, W Huang, J Wang, W Lu Tetrahedron letters 47 (25), 4153-4155, 2006 | 25 | 2006 |
Charge shielding of PIP2 by cations regulates enzyme activity of phospholipase C JB Seo, SR Jung, W Huang, Q Zhang, DS Koh Biophysical Journal 108 (2), 257a, 2015 | 24 | 2015 |
Isotope-coded, fluorous photoaffinity labeling reagents Z Song, W Huang, Q Zhang Chemical Communications, 2012 | 22 | 2012 |
A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes W Huang, X Wang, S Endo-Streeter, M Barrett, J Waybright, C Wohlfeld, ... Journal of Biological Chemistry 293 (5), 1728-1735, 2018 | 17 | 2018 |
Synthesis of tanshinone IIA analogues and their inhibitory activities against Cdc25 phosphatases WG Huang, JY Li, Y Luo, J Li, W Lu Chinese Chemical Letters 20 (12), 1461-1464, 2009 | 13 | 2009 |
A Novel Antiparasitic Compound Kills Ring-Stage Plasmodium falciparum and Retains Activity Against Artemisinin-Resistant Parasites RL Clements, V Streva, P Dumoulin, W Huang, E Owens, DK Raj, ... The Journal of infectious diseases 221 (6), 956-962, 2020 | 11 | 2020 |
Total synthesis of miltirone WG Huang, YF Li, W Lu, HA Aisa Chemistry of natural compounds 42, 665-667, 2006 | 10 | 2006 |
“Fix and Click” for assay of sphingolipid signaling in single primary human intestinal epithelial cells LA Gallion, Y Wang, A Massaro, M Yao, BV Petersen, Q Zhang, W Huang, ... Analytical chemistry 94 (3), 1594-1600, 2022 | 7 | 2022 |
A high-throughput assay to identify allosteric inhibitors of the PLC-γ isozymes operating at membranes W Huang, AJ Carr, N Hajicek, M Sokolovski, E Siraliev-Perez, PB Hardy, ... Biochemistry 59 (41), 4029-4038, 2020 | 6 | 2020 |
Fluorous enzymatic synthesis of phosphatidylinositides W Huang, A Proctor, CE Sims, NL Allbritton, Q Zhang Chemical communications 50 (22), 2928-2931, 2014 | 6 | 2014 |