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Weigang Huang
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Synthesis and anti-hepatitis B virus activity of novel benzimidazole derivatives
YF Li, GF Wang, PL He, WG Huang, FH Zhu, HY Gao, W Tang, Y Luo, ...
Journal of medicinal chemistry 49 (15), 4790-4794, 2006
2062006
Synthesis and biological evaluation of (±)-cryptotanshinone and its simplified analogues as potent CDC25 inhibitors
WG Huang, YY Jiang, Q Li, J Li, JY Li, W Lu, JC Cai
Tetrahedron 61 (7), 1863-1870, 2005
642005
Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations
N Hajicek, NC Keith, E Siraliev-Perez, BRS Temple, W Huang, Q Zhang, ...
Elife 8, e51700, 2019
632019
Identification of 1-isopropylsulfonyl-2-amine benzimidazoles as a new class of inhibitors of hepatitis B virus
YF Li, GF Wang, Y Luo, WG Huang, W Tang, CL Feng, LP Shi, YD Ren, ...
European journal of medicinal chemistry 42 (11-12), 1358-1364, 2007
582007
Small Molecule Inhibitors of Phospholipase C from a Novel High-throughput Screen
W Huang, M Barrett, N Hajicek, S Hicks, TK Harden, J Sondek, Q Zhang
Journal of Biological Chemistry, 2013
462013
Membrane-induced allosteric control of phospholipase C-β isozymes
TH Charpentier, GL Waldo, MO Barrett, W Huang, Q Zhang, TK Harden, ...
Journal of Biological Chemistry 289 (43), 29545-29557, 2014
382014
Synthesis of miltirone analogues as inhibitors of Cdc25 phosphatases
W Huang, J Li, W Zhang, Y Zhou, C Xie, Y Luo, Y Li, J Wang, J Li, W Lu
Bioorganic & medicinal chemistry letters 16 (7), 1905-1908, 2006
352006
A Fluorogenic, Small Molecule Reporter for Mammalian Phospholipase C Isozymes
W Huang, SN Hicks, JE Sondek, Q Zhang
ACS Chemical Biology, 2010
342010
Kinetic analysis of PI3K reactions with fluorescent PIP 2 derivatives
W Huang, D Jiang, X Wang, K Wang, CE Sims, NL Allbritton, Q Zhang
Analytical and Bioanalytical Chemistry, 1-8, 2011
312011
Copper-free Sonogashira reaction using 7-chloro camptothecins
Y Luo, H Gao, Y Li, W Huang, W Lu, Z Zhang
Tetrahedron 62 (11), 2465-2470, 2006
302006
Total synthesis of mallotophilippen C
Y Li, Y Luo, W Huang, J Wang, W Lu
Tetrahedron letters 47 (25), 4153-4155, 2006
252006
Charge shielding of PIP2 by cations regulates enzyme activity of phospholipase C
JB Seo, SR Jung, W Huang, Q Zhang, DS Koh
Biophysical Journal 108 (2), 257a, 2015
242015
Isotope-coded, fluorous photoaffinity labeling reagents
Z Song, W Huang, Q Zhang
Chemical Communications, 2012
222012
A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes
W Huang, X Wang, S Endo-Streeter, M Barrett, J Waybright, C Wohlfeld, ...
Journal of Biological Chemistry 293 (5), 1728-1735, 2018
172018
Synthesis of tanshinone IIA analogues and their inhibitory activities against Cdc25 phosphatases
WG Huang, JY Li, Y Luo, J Li, W Lu
Chinese Chemical Letters 20 (12), 1461-1464, 2009
132009
A Novel Antiparasitic Compound Kills Ring-Stage Plasmodium falciparum and Retains Activity Against Artemisinin-Resistant Parasites
RL Clements, V Streva, P Dumoulin, W Huang, E Owens, DK Raj, ...
The Journal of infectious diseases 221 (6), 956-962, 2020
112020
Total synthesis of miltirone
WG Huang, YF Li, W Lu, HA Aisa
Chemistry of natural compounds 42, 665-667, 2006
102006
“Fix and Click” for assay of sphingolipid signaling in single primary human intestinal epithelial cells
LA Gallion, Y Wang, A Massaro, M Yao, BV Petersen, Q Zhang, W Huang, ...
Analytical chemistry 94 (3), 1594-1600, 2022
72022
A high-throughput assay to identify allosteric inhibitors of the PLC-γ isozymes operating at membranes
W Huang, AJ Carr, N Hajicek, M Sokolovski, E Siraliev-Perez, PB Hardy, ...
Biochemistry 59 (41), 4029-4038, 2020
62020
Fluorous enzymatic synthesis of phosphatidylinositides
W Huang, A Proctor, CE Sims, NL Allbritton, Q Zhang
Chemical communications 50 (22), 2928-2931, 2014
62014
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