| Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size H Cabral, Y Matsumoto, K Mizuno, Q Chen, M Murakami, M Kimura, ... Nature nanotechnology 6 (12), 815-823, 2011 | 2433 | 2011 |
| Janus “nano-bullets” for magnetic targeting liver cancer chemotherapy S Dan, L Jing, Z Xiao, P Yue, W Zheng, Z Ming, C Qixian, W Dong, C Li Biomaterials 100, 118-133, 2016 | 160 | 2016 |
| Nitroxide-based macromolecular contrast agents with unprecedented transverse relaxivity and stability for magnetic resonance imaging of tumors HVT Nguyen, Q Chen, JT Paletta, P Harvey, Y Jiang, H Zhang, MD Boska, ... ACS Central Science 3 (7), 800-811, 2017 | 151 | 2017 |
| Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors Z Ge, Q Chen, K Osada, X Liu, TA Tockary, S Uchida, A Dirisala, T Ishii, ... Biomaterials 35 (10), 3416-3426, 2014 | 134 | 2014 |
| Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles F Pittella, K Miyata, Y Maeda, T Suma, S Watanabe, Q Chen, RJ Christie, ... Journal of controlled release 161 (3), 868-874, 2012 | 130 | 2012 |
| Tethered PEG crowdedness determining shape and blood circulation profile of polyplex micelle gene carriers TA Tockary, K Osada, Q Chen, K Machitani, A Dirisala, S Uchida, ... Macromolecules 46 (16), 6585-6592, 2013 | 117 | 2013 |
| Self-sufficing H2O2-responsive nanocarriers through tumor-specific H2O2 production for synergistic oxidation-chemotherapy J Li, W Ke, L Wang, M Huang, W Yin, P Zhang, Q Chen, Z Ge Journal of controlled release 225, 64-74, 2016 | 108 | 2016 |
| PEGylated polyplex with optimized PEG shielding enhances gene introduction in lungs by minimizing inflammatory responses S Uchida, K Itaka, Q Chen, K Osada, T Ishii, MA Shibata, M Harada-Shiba, ... Molecular Therapy 20 (6), 1196-1203, 2012 | 79 | 2012 |
| A targeted and stable polymeric nanoformulation enhances systemic delivery of mRNA to tumors Q Chen, R Qi, X Chen, X Yang, S Wu, H Xiao, W Dong Molecular Therapy 25 (1), 92-101, 2017 | 78 | 2017 |
| Biodegradable synthetic antimicrobial with aggregation-induced emissive luminogens for temporal antibacterial activity and facile bacteria detection S Chen, Q Chen, Q Li, J An, P Sun, J Ma, H Gao Chemistry of Materials 30 (5), 1782-1790, 2018 | 76 | 2018 |
| Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer R Qi, Y Wang, PM Bruno, H Xiao, Y Yu, T Li, S Lauffer, W Wei, Q Chen, ... Nature communications 8 (1), 2166, 2017 | 76 | 2017 |
| Mitochondria-targeted smart AIEgens: Imaging and therapeutics H Li, H Kim, C Zhang, S Zeng, Q Chen, L Jia, J Wang, X Peng, J Yoon Coordination Chemistry Reviews 473, 214818, 2022 | 72 | 2022 |
| Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors A Dirisala, K Osada, Q Chen, TA Tockary, K Machitani, S Osawa, X Liu, ... Biomaterials 35 (20), 5359-5368, 2014 | 68 | 2014 |
| Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors Q Chen, K Osada, T Ishii, M Oba, S Uchida, TA Tockary, T Endo, Z Ge, ... Biomaterials 33 (18), 4722-4730, 2012 | 68 | 2012 |
| Ternary polyplex micelles with PEG shells and intermediate barrier to complexed DNA cores for efficient systemic gene delivery J Li, Q Chen, Z Zha, H Li, K Toh, A Dirisala, Y Matsumoto, K Osada, ... Journal of Controlled Release 209, 77-87, 2015 | 67 | 2015 |
| Dual endogenous stimuli-responsive polyplex micelles as smart two-step delivery nanocarriers for deep tumor tissue penetration and combating drug resistance of cisplatin J Li, Y Han, Q Chen, H Shi, S ur Rehman, M Siddiq, Z Ge, S Liu Journal of Materials Chemistry B 2 (13), 1813-1824, 2014 | 62 | 2014 |
| Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting Q Chen, K Osada, Z Ge, S Uchida, TA Tockary, A Dirisala, A Matsui, K Toh, ... Biomaterials 113, 253-265, 2017 | 60 | 2017 |
| ABC triblock bottlebrush copolymer-based injectable hydrogels: design, synthesis, and application to expanding the therapeutic index of cancer immunochemotherapy F Vohidov, LE Milling, Q Chen, W Zhang, S Bhagchandani, HVT Nguyen, ... Chemical Science 11 (23), 5974-5986, 2020 | 51 | 2020 |
| Bottlebrush polymers with flexible enantiomeric side chains display differential biological properties HVT Nguyen, Y Jiang, S Mohapatra, W Wang, JC Barnes, NJ Oldenhuis, ... Nature Chemistry 14 (1), 85-93, 2022 | 50 | 2022 |
| Combination of chondroitin sulfate and polyplex micelles from Poly (ethylene glycol)-poly {N’-[N-(2-aminoethyl)-2-aminoethyl] aspartamide} block copolymer for prolonged in vivo … S Uchida, K Itaka, Q Chen, K Osada, K Miyata, T Ishii, M Harada-Shiba, ... Journal of controlled release 155 (2), 296-302, 2011 | 48 | 2011 |
Kazunori KataokaDirector General, Innovation Center of NanoMed; Professor Emeritus, Univ. TokyoVerified email at bmw.t.u-tokyo.ac.jp
