| A protein sensor for siRNA asymmetry Y Tomari, C Matranga, B Haley, N Martinez, PD Zamore Science 306 (5700), 1377-1380, 2004 | 819 | 2004 |
| The interplay between transcription factors and microRNAs in genome‐scale regulatory networks NJ Martinez, AJM Walhout Bioessays 31 (4), 435-445, 2009 | 300 | 2009 |
| A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity NJ Martinez, MC Ow, MI Barrasa, M Hammell, R Sequerra, ... Genes & development 22 (18), 2535-2549, 2008 | 290 | 2008 |
| A gene-centered C. elegans protein-DNA interaction network B Deplancke, A Mukhopadhyay, W Ao, AM Elewa, CA Grove, NJ Martinez, ... Cell 125 (6), 1193-1205, 2006 | 279 | 2006 |
| Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity NJ Martinez, MC Ow, JS Reece-Hoyes, MI Barrasa, VR Ambros, ... Genome research 18 (12), 2005-2015, 2008 | 253 | 2008 |
| A stele‐enriched gene regulatory network in the Arabidopsis root SM Brady, L Zhang, M Megraw, NJ Martinez, E Jiang, CS Yi, W Liu, ... Molecular Systems Biology 7 (1), 459, 2011 | 183 | 2011 |
| Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation HM Chang, NJ Martinez, JE Thornton, JP Hagan, KD Nguyen, RI Gregory Nature communications 3 (1), 923, 2012 | 171 | 2012 |
| MicroRNA gene regulatory pathways in the establishment and maintenance of ESC identity NJ Martinez, RI Gregory Cell stem cell 7 (1), 31-35, 2010 | 169 | 2010 |
| Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia LH Castilla, P Perrat, NJ Martinez, SF Landrette, R Keys, S Oikemus, ... Proceedings of the National Academy of Sciences 101 (14), 4924-4929, 2004 | 164 | 2004 |
| Argonaute2 expression is post-transcriptionally coupled to microRNA abundance NJ Martinez, RI Gregory Rna 19 (5), 605-612, 2013 | 142 | 2013 |
| A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase NJ Martinez, RR Asawa, MG Cyr, A Zakharov, DJ Urban, JS Roth, ... Scientific reports 8 (1), 9472, 2018 | 89 | 2018 |
| Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays DJ Urban, NJ Martinez, MI Davis, KR Brimacombe, DM Cheff, TD Lee, ... Scientific reports 7 (1), 12758, 2017 | 81 | 2017 |
| Gateway-compatible yeast one-hybrid screens B Deplancke, V Vermeirssen, HE Arda, NJ Martinez, AJM Walhout Cold Spring Harbor Protocols 2006 (5), pdb. prot4590, 2006 | 80 | 2006 |
| Discovery of orally bioavailable, quinoline-based aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with potent cellular activity SM Yang, NJ Martinez, A Yasgar, C Danchik, C Johansson, Y Wang, ... Journal of medicinal chemistry 61 (11), 4883-4903, 2018 | 75 | 2018 |
| Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping V Vermeirssen, B Deplancke, MI Barrasa, JS Reece-Hoyes, HE Arda, ... Nature methods 4 (8), 659-664, 2007 | 74 | 2007 |
| The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans MC Ow, NJ Martinez, PH Olsen, HS Silverman, MI Barrasa, B Conradt, ... Genes & development 22 (18), 2520-2534, 2008 | 71 | 2008 |
| High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models NJ Martinez, SA Titus, AK Wagner, A Simeonov Expert opinion on drug discovery 10 (12), 1347-1361, 2015 | 60 | 2015 |
| The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly NJ Martinez, HM Chang, J de Riba Borrajo, RI Gregory Rna 19 (11), 1583-1593, 2013 | 58 | 2013 |
| Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models L Yu, X Zhang, Y Yang, D Li, K Tang, Z Zhao, W He, C Wang, N Sahoo, ... Science advances 6 (6), eaaz2736, 2020 | 42 | 2020 |
| Critical assessment of artificial intelligence methods for prediction of hERG channel inhibition in the “big data” era VB Siramshetty, DT Nguyen, NJ Martinez, NT Southall, A Simeonov, ... Journal of Chemical Information and Modeling 60 (12), 6007-6019, 2020 | 38 | 2020 |
