Luis Galietta
Luis Galietta
Istituto Giannina Gaslini
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TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity
A Caputo, E Caci, L Ferrera, N Pedemonte, C Barsanti, E Sondo, U Pfeffer, ...
Science 322 (5901), 590-594, 2008
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin–induced intestinal fluid secretion
T Ma, JR Thiagarajah, H Yang, ND Sonawane, C Folli, LJV Galietta, ...
The Journal of clinical investigation 110 (11), 1651-1658, 2002
Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening
N Pedemonte, GL Lukacs, K Du, E Caci, O Zegarra-Moran, LJV Galietta, ...
The Journal of clinical investigation 115 (9), 2564-2571, 2005
Chloride channels as drug targets
AS Verkman, LJV Galietta
Nature reviews Drug discovery 8 (2), 153-171, 2009
Structure and function of TMEM16 proteins (anoctamins)
N Pedemonte, LJV Galietta
Physiological reviews 94 (2), 419-459, 2014
Green fluorescent protein-based halide indicators with improved chloride and iodide affinities
LJV Galietta, PM Haggie, AS Verkman
FEBS letters 499 (3), 220-224, 2001
Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure–activity analysis, and in vivo efficacy
C Muanprasat, ND Sonawane, D Salinas, A Taddei, LJV Galietta, ...
The Journal of general physiology 124 (2), 125-137, 2004
Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists
LVJ Galietta, S Jayaraman, AS Verkman
American Journal of Physiology-Cell Physiology 281 (5), C1734-C1742, 2001
Nanomolar affinity small molecule correctors of defective ΔF508-CFTR chloride channel gating
H Yang, AA Shelat, RK Guy, VS Gopinath, T Ma, K Du, GL Lukacs, ...
Journal of Biological Chemistry 278 (37), 35079-35085, 2003
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening
T Ma, L Vetrivel, H Yang, N Pedemonte, O Zegarra-Moran, LJV Galietta, ...
Journal of Biological Chemistry 277 (40), 37235-37241, 2002
Regulation of TMEM16A chloride channel properties by alternative splicing
L Ferrera, A Caputo, I Ubby, E Bussani, O Zegarra-Moran, R Ravazzolo, ...
Journal of Biological Chemistry 284 (48), 33360-33368, 2009
Novel CFTR Chloride Channel Activators Identified by Screening of Combinatorial Libraries Based on Flavone and Benzoquinolizinium Lead Compounds* 210
LJV Galietta, MF Springsteel, M Eda, EJ Niedzinski, MJ Haddadin, ...
Journal of Biological Chemistry 276 (23), 19723-19728, 2001
Phenylglycine and sulfonamide correctors of defective ΔF508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating
N Pedemonte, ND Sonawane, A Taddei, J Hu, O Zegarra-Moran, YF Suen, ...
Molecular pharmacology 67 (5), 1797-1807, 2005
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells
X Fang, Y Song, J Hirsch, LJV Galietta, N Pedemonte, RL Zemans, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 290 (2 …, 2006
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia
P Scudieri, E Caci, S Bruno, L Ferrera, M Schiavon, E Sondo, V Tomati, ...
The Journal of physiology 590 (23), 6141-6155, 2012
Targeting ion channels in cystic fibrosis
MA Mall, LJV Galietta
Journal of Cystic Fibrosis 14 (5), 561-570, 2015
IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro
LJV Galietta, P Pagesy, C Folli, E Caci, L Romio, B Costes, E Nicolis, ...
The Journal of Immunology 168 (2), 839-845, 2002
Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channels
N Pedemonte, E Caci, E Sondo, A Caputo, K Rhoden, U Pfeffer, ...
The Journal of Immunology 178 (8), 5144-5153, 2007
TMEM16A Protein: A New Identity for Ca2+-Dependent Cl Channels
L Ferrera, A Caputo, LJV Galietta
Physiology 25 (6), 357-363, 2010
Correction of delF508-CFTR activity with benzo (c) quinolizinium compounds through facilitation of its processing in cystic fibrosis airway cells
RL Dormer, R Dérand, CM McNeilly, Y Mettey, L Bulteau-Pignoux, ...
Journal of Cell Science 114 (22), 4073-4081, 2001
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