Direct observation of adaptive tracking on ecological timescales in Drosophila SM Rudman, SI Greenblum, S Rajpurohit, NJ Betancourt, J Hanna, S Tilk, ... Science 375 (6586), eabj7484, 2022 | 151 | 2022 |
Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila HE Machado, AO Bergland, R Taylor, S Tilk, E Behrman, K Dyer, ... Elife 10, e67577, 2021 | 135* | 2021 |
Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy JL Caswell-Jin, K McNamara, JG Reiter, R Sun, Z Hu, Z Ma, J Ding, ... Nature communications 10 (1), 657, 2019 | 62 | 2019 |
Deep sequencing of natural and experimental populations of Drosophila melanogaster reveals biases in the spectrum of new mutations ZJ Assaf, S Tilk, J Park, ML Siegal, D Petrov Genome research, gr. 219956.116, 2017 | 46 | 2017 |
Accurate allele frequencies from ultra-low coverage pool-seq samples in evolve-and-resequence experiments S Tilk, A Bergland, A Goodman, P Schmidt, D Petrov, S Greenblum G3: Genes, Genomes, Genetics 9 (12), 4159-4168, 2019 | 37 | 2019 |
Most cancers carry a substantial deleterious load due to Hill-Robertson interference S Tilk, S Tkachenko, C Curtis, DA Petrov, CD McFarland elife 11, e67790, 2022 | 28 | 2022 |
Cancers adapt to their mutational load by buffering protein misfolding stress S Tilk, J Frydman, C Curtis, DA Petrov Elife 12, RP87301, 2024 | 6 | 2024 |
Accurate, ultra-low coverage genome reconstruction and association studies in Hybrid Swarm mapping populations CA Weller, S Tilk, S Rajpurohit, AO Bergland G3 11 (4), jkab062, 2021 | 5 | 2021 |
Discovery of ULBP6 as a novel immuno-oncology target using pleiotropic signals from 23andMe’s genetic and health survey database S Tilk, P Fontanillas, WJ Chung, C Hom, S Shi, A Diep, K Gerrick, ... Cancer Research 84 (6_Supplement), 3903-3903, 2024 | | 2024 |
Pervasive fitness trade-offs revealed by rapid adaption in large experimental populations of Drosophila melanogaster MC Bitter, S Greenblum, S Rajpurohit, AO Bergland, JA Hemker, ... Biorxiv, 2024.10. 28.620721, 2024 | | 2024 |
Systems and Methods for Assessing Mutational Burden of Neoplasms And Associated Treatments Thereof S Tilk, DA Petrov, J Frydman, C Curtis US Patent App. 18/320,148, 2023 | | 2023 |
Causes and Consequences of Damaging Mutation Accumulation in Cancer S Tilk Stanford University, 2022 | | 2022 |