Specific chemical and structural damage to proteins produced by synchrotron radiation M Weik, RBG Ravelli, G Kryger, S McSweeney, ML Raves, M Harel, ... Proceedings of the National Academy of Sciences 97 (2), 623-628, 2000 | 625 | 2000 |
Protein dynamics studied by neutron scattering F Gabel, D Bicout, U Lehnert, M Tehei, M Weik, G Zaccai Quarterly reviews of biophysics 35 (4), 327-367, 2002 | 409 | 2002 |
The role of protein dynamics in the evolution of new enzyme function E Campbell, M Kaltenbach, GJ Correy, PD Carr, BT Porebski, ... Nature chemical biology 12 (11), 944-950, 2016 | 304 | 2016 |
Translational diffusion of hydration water correlates with functional motions in folded and intrinsically disordered proteins G Schirò, Y Fichou, FX Gallat, K Wood, F Gabel, M Moulin, M Härtlein, ... Nature communications 6 (1), 6490, 2015 | 243 | 2015 |
Structural insights into substrate traffic and inhibition in acetylcholinesterase JP Colletier, D Fournier, HM Greenblatt, J Stojan, JL Sussman, G Zaccai, ... The EMBO journal 25 (12), 2746-2756, 2006 | 235 | 2006 |
Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography N Coquelle, M Sliwa, J Woodhouse, G Schirò, V Adam, A Aquila, ... Nature Chemistry 10 (1), 31-37, 2018 | 207 | 2018 |
Coincidence of dynamical transitions in a soluble protein and its hydration water: direct measurements by neutron scattering and MD simulations K Wood, A Frölich, A Paciaroni, M Moulin, M Härtlein, G Zaccai, DJ Tobias, ... Journal of the American Chemical Society 130 (14), 4586-4587, 2008 | 205 | 2008 |
Thermal motions in bacteriorhodopsin at different hydration levels studied by neutron scattering: correlation with kinetics and light-induced conformational changes U Lehnert, V Réat, M Weik, G Zaccai, C Pfister Biophysical journal 75 (4), 1945-1952, 1998 | 172 | 1998 |
Coupling of protein and hydration-water dynamics in biological membranes K Wood, M Plazanet, F Gabel, B Kessler, D Oesterhelt, DJ Tobias, ... Proceedings of the National Academy of Sciences 104 (46), 18049-18054, 2007 | 171 | 2007 |
Snapshots of enzymatic Baeyer-Villiger catalysis: oxygen activation and intermediate stabilization R Orru, HM Dudek, C Martinoli, DET Pazmiño, A Royant, M Weik, ... Journal of Biological Chemistry 286 (33), 29284-29291, 2011 | 158 | 2011 |
Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics Y Xu, JP Colletier, M Weik, H Jiang, J Moult, I Silman, JL Sussman Biophysical Journal 95 (5), 2500-2511, 2008 | 148 | 2008 |
Mechanisms of cholinesterase inhibition by inorganic mercury MF Frasco, JP Colletier, M Weik, F Carvalho, L Guilhermino, J Stojan, ... the FEBS Journal 274 (7), 1849-1861, 2007 | 147 | 2007 |
Mechanism and dynamics of fatty acid photodecarboxylase D Sorigué, K Hadjidemetriou, S Blangy, G Gotthard, A Bonvalet, ... Science 372 (6538), eabd5687, 2021 | 145 | 2021 |
Structure and function of an insect α-carboxylesterase (αEsterase7) associated with insecticide resistance CJ Jackson, JW Liu, PD Carr, F Younus, C Coppin, T Meirelles, M Lethier, ... Proceedings of the National Academy of Sciences 110 (25), 10177-10182, 2013 | 144 | 2013 |
Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments N Coquelle, E Fioravanti, M Weik, F Vellieux, D Madern Journal of Molecular Biology 374 (2), 547-562, 2007 | 143 | 2007 |
Megahertz data collection from protein microcrystals at an X-ray free-electron laser ML Grünbein, J Bielecki, A Gorel, M Stricker, R Bean, M Cammarata, ... Nature communications 9 (1), 3487, 2018 | 122 | 2018 |
Evidence for the formation of disulfide radicals in protein crystals upon X-ray irradiation M Weik, J Berges, ML Raves, P Gros, S McSweeney, I Silman, ... Journal of Synchrotron Radiation 9 (6), 342-346, 2002 | 121 | 2002 |
Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime B Sanson, F Nachon, JP Colletier, MT Froment, L Toker, HM Greenblatt, ... Journal of medicinal chemistry 52 (23), 7593-7603, 2009 | 115 | 2009 |
Localization of glycolipids in membranes by in vivo labeling and neutron diffraction M Weik, H Patzelt, G Zaccai, D Oesterhelt Molecular cell 1 (3), 411-419, 1998 | 109 | 1998 |
Radiation damage and dose limits in serial synchrotron crystallography at cryo-and room temperatures E de La Mora, N Coquelle, CS Bury, M Rosenthal, JM Holton, ... Proceedings of the National Academy of Sciences 117 (8), 4142-4151, 2020 | 106 | 2020 |