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Wei-Lei Yang, Ph.D.
Wei-Lei Yang, Ph.D.
AIxMed, Inc.
Verified email at aixmed.com
Title
Cited by
Cited by
Year
The E3 ligase TRAF6 regulates Akt ubiquitination and activation
WL Yang, J Wang, CH Chan, SW Lee, AD Campos, B Lamothe, L Hur, ...
Science 325 (5944), 1134, 2009
6372009
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence
HK Lin, Z Chen, G Wang, C Nardella, SW Lee, CH Chan, WL Yang, ...
Nature 464 (7287), 374-379, 2010
4722010
The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis
CH Chan, CF Li, WL Yang, Y Gao, SW Lee, Z Feng, HY Huang, KKC Tsai, ...
Cell 149 (5), 1098-1111, 2012
4172012
Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB
HK Lin, G Wang, Z Chen, J Teruya-Feldstein, Y Liu, CH Chan, WL Yang, ...
Nature cell biology 11 (4), 420-432, 2009
2752009
Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis
CH Chan, SW Lee, CF Li, J Wang, WL Yang, CY Wu, J Wu, KI Nakayama, ...
Nature cell biology 12 (5), 457-467, 2010
2362010
Toll‐like receptor‐mediated IRE1α activation as a therapeutic target for inflammatory arthritis
Q Qiu, Z Zheng, L Chang, YS Zhao, C Tan, A Dandekar, Z Zhang, Z Lin, ...
The EMBO journal 32 (18), 2477-2490, 2013
2042013
Regulation of Akt signaling activation by ubiquitination
WL Yang, CY Wu, J Wu, HK Lin
Cell Cycle 9 (3), 486-497, 2010
1712010
The role of biomarkers in the management of epithelial ovarian cancer
WL Yang, Z Lu, RC Bast Jr
Expert review of molecular diagnostics 17 (6), 577-591, 2017
1542017
Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress
SW Lee, CF Li, G Jin, Z Cai, F Han, CH Chan, WL Yang, BK Li, ...
Molecular cell 57 (6), 1022-1033, 2015
1282015
Skp2–MacroH2A1–CDK8 axis orchestrates G2/M transition and tumorigenesis
D Xu, CF Li, X Zhang, Z Gong, CH Chan, SW Lee, G Jin, AH Rezaeian, ...
Nature communications 6 (1), 6641, 2015
1122015
Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development
WL Yang, X Zhang, HK Lin
Oncogene 29 (32), 4493-4503, 2010
1122010
Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response
CY Wu, HY Kang, WL Yang, J Wu, YS Jeong, J Wang, CH Chan, SW Lee, ...
Journal of Biological Chemistry 286 (35), 30806-30815, 2011
992011
Cycles of ubiquitination and deubiquitination critically regulate growth factor–mediated activation of Akt signaling
WL Yang, G Jin, CF Li, YS Jeong, A Moten, D Xu, Z Feng, W Chen, Z Cai, ...
Science signaling 6 (257), ra3-ra3, 2013
732013
The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal
J Wang, F Han, J Wu, SW Lee, CH Chan, CY Wu, WL Yang, Y Gao, ...
Blood, The Journal of the American Society of Hematology 118 (20), 5429-5438, 2011
632011
Elevation of TP53 autoantibody before CA125 in preclinical invasive epithelial ovarian cancer
WL Yang, A Gentry-Maharaj, A Simmons, A Ryan, EO Fourkala, Z Lu, ...
Clinical Cancer Research 23 (19), 5912-5922, 2017
582017
Foxo3a transcription factor is a negative regulator of Skp2 and Skp2 SCF complex
J Wu, SW Lee, X Zhang, F Han, SY Kwan, X Yuan, WL Yang, YS Jeong, ...
Oncogene 32 (1), 78-85, 2013
402013
Bortezomib enhances radiosensitivity in oral cancer through inducing autophagy-mediated TRAF6 oncoprotein degradation
YH Wu, WS Wu, LC Lin, CS Liu, SY Ho, BJ Wang, BM Huang, YL Yeh, ...
Journal of Experimental & Clinical Cancer Research 37, 1-14, 2018
292018
Human epididymis protein 4 antigen‐autoantibody complexes complement cancer antigen 125 for detecting early‐stage ovarian cancer
WL Yang, Z Lu, J Guo, BM Fellman, J Ning, KH Lu, U Menon, ...
Cancer 126 (4), 725-736, 2020
282020
Osteopontin, macrophage migration inhibitory factor and anti-interleukin-8 autoantibodies complement CA125 for detection of early stage ovarian cancer
J Guo, WL Yang, D Pak, J Celestino, KH Lu, J Ning, AE Lokshin, Z Cheng, ...
Cancers 11 (5), 596, 2019
262019
Multi-marker longitudinal algorithms incorporating HE4 and CA125 in ovarian cancer screening of postmenopausal women
A Gentry-Maharaj, O Blyuss, A Ryan, M Burnell, C Karpinskyj, R Gunu, ...
Cancers 12 (7), 1931, 2020
212020
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