| CellProfiler: image analysis software for identifying and quantifying cell phenotypes AE Carpenter, TR Jones, MR Lamprecht, C Clarke, IH Kang, O Friman, ... Genome biology 7, 1-11, 2006 | 5051 | 2006 |
| A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen J Moffat, DA Grueneberg, X Yang, SY Kim, AM Kloepfer, G Hinkle, ... Cell 124 (6), 1283-1298, 2006 | 1914 | 2006 |
| Opportunities and obstacles for deep learning in biology and medicine T Ching, DS Himmelstein, BK Beaulieu-Jones, AA Kalinin, BT Do, ... Journal of The Royal Society Interface 15 (141), 20170387, 2018 | 1511 | 2018 |
| CellProfiler 3.0: Next-generation image processing for biology C McQuin, A Goodman, V Chernyshev, L Kamentsky, BA Cimini, ... PLoS biology 16 (7), e2005970, 2018 | 1373 | 2018 |
| mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway TR Peterson, SS Sengupta, TE Harris, AE Carmack, SA Kang, E Balderas, ... Cell 146 (3), 408-420, 2011 | 1172 | 2011 |
| Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software L Kamentsky, TR Jones, A Fraser, MA Bray, DJ Logan, KL Madden, ... Bioinformatics 27 (8), 1179-1180, 2011 | 1060 | 2011 |
| CellProfiler™: free, versatile software for automated biological image analysis MR Lamprecht, DM Sabatini, AE Carpenter Biotechniques 42 (1), 71-75, 2007 | 980 | 2007 |
| Long-range directional movement of an interphase chromosome site CH Chuang, AE Carpenter, B Fuchsova, T Johnson, P de Lanerolle, ... Current Biology 16 (8), 825-831, 2006 | 596 | 2006 |
| Biological imaging software tools KW Eliceiri, MR Berthold, IG Goldberg, L Ibáñez, BS Manjunath, ... Nature methods 9 (7), 697-710, 2012 | 576 | 2012 |
| CellProfiler Analyst: data exploration and analysis software for complex image-based screens T Jones, I Kang, D Wheeler, R Lindquist, A Papallo, D Sabatini, P Golland, ... BMC bioinformatics 9 (1), 482, 2008 | 576 | 2008 |
| In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication AE Baltus, DB Menke, YC Hu, ML Goodheart, AE Carpenter, DG de Rooij, ... Nature genetics 38 (12), 1430-1434, 2006 | 529 | 2006 |
| Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes MA Bray, S Singh, H Han, CT Davis, B Borgeson, C Hartland, ... Nature protocols 11 (9), 1757-1774, 2016 | 498 | 2016 |
| Data-analysis strategies for image-based cell profiling JC Caicedo, S Cooper, F Heigwer, S Warchal, P Qiu, C Molnar, ... Nature methods 14 (9), 849-863, 2017 | 479 | 2017 |
| Annotated high-throughput microscopy image sets for validation. V Ljosa, KL Sokolnicki, AE Carpenter Nature methods 9 (7), 637-637, 2012 | 428 | 2012 |
| Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning TR Jones, AE Carpenter, MR Lamprecht, J Moffat, SJ Silver, JK Grenier, ... Proceedings of the National Academy of Sciences 106 (6), 1826-1831, 2009 | 425 | 2009 |
| Systematic genome-wide screens of gene function AE Carpenter, DM Sabatini Nature Reviews Genetics 5 (1), 11-22, 2004 | 396 | 2004 |
| An algorithm-based topographical biomaterials library to instruct cell fate HV Unadkat, M Hulsman, K Cornelissen, BJ Papenburg, ... Proceedings of the National Academy of Sciences 108 (40), 16565-16570, 2011 | 387 | 2011 |
| Nucleus segmentation across imaging experiments: the 2018 Data Science Bowl JC Caicedo, A Goodman, KW Karhohs, BA Cimini, J Ackerman, ... Nature methods 16 (12), 1247-1253, 2019 | 369 | 2019 |
| Visualization of image data from cells to organisms T Walter, DW Shattuck, R Baldock, ME Bastin, AE Carpenter, S Duce, ... Nature methods 7 (Suppl 3), S26-S41, 2010 | 308 | 2010 |
| The bromodomain protein Brd4 insulates chromatin from DNA damage signalling SR Floyd, ME Pacold, Q Huang, SM Clarke, FC Lam, IG Cannell, ... Nature 498 (7453), 246-250, 2013 | 303 | 2013 |
Shantanu SinghSenior Group Leader, Broad Institute of MIT and HarvardVerified email at broad.mit.edu
