Spiroindolones, a potent compound class for the treatment of malaria M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ... science 329 (5996), 1175-1180, 2010 | 1202 | 2010 |
Proteome-wide covalent ligand discovery in native biological systems KM Backus, BE Correia, KM Lum, S Forli, BD Horning, GE González-Páez, ... Nature 534 (7608), 570-574, 2016 | 734 | 2016 |
Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites NV Dharia, D Plouffe, SER Bopp, GE González-Páez, C Lucas, C Salas, ... Genome research 20 (11), 1534-1544, 2010 | 75 | 2010 |
Selective detection of caspase-3 versus caspase-7 using activity-based probes with key unnatural amino acids CJ Vickers, GE González-Páez, DW Wolan ACS chemical biology 8 (7), 1558-1566, 2013 | 52 | 2013 |
Selective detection and inhibition of active caspase-3 in cells with optimized peptides CJ Vickers, GE Gonzalez-Paez, DW Wolan Journal of the American Chemical Society 135 (34), 12869-12876, 2013 | 49 | 2013 |
Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum T Pholcharee, D Oyen, Y Flores-Garcia, G Gonzalez-Paez, Z Han, ... Nature communications 12 (1), 1063, 2021 | 36 | 2021 |
Discovery of a highly selective caspase-3 substrate for imaging live cells CJ Vickers, GE González-Páez, DW Wolan ACS Chemical Biology 9 (10), 2199-2203, 2014 | 34 | 2014 |
Spiroindolones, a new and potent chemotype for the treatment of malaria M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ... Science (New York, NY) 329 (5996), 1175, 2010 | 32 | 2010 |
Diverse antibody responses to conserved structural motifs in Plasmodium falciparum circumsporozoite protein T Pholcharee, D Oyen, JL Torres, Y Flores-Garcia, GM Martin, ... Journal of molecular biology 432 (4), 1048-1063, 2020 | 27 | 2020 |
Substrate profiling and high resolution co-complex crystal structure of a secreted C11 protease conserved across commensal bacteria EJ Roncase, C Moon, S Chatterjee, GE González-Páez, CS Craik, ... ACS chemical biology 12 (6), 1556-1565, 2017 | 25 | 2017 |
Selective and rapid cell-permeable inhibitor of human caspase-3 A Solania, GE González-Páez, DW Wolan ACS chemical biology 14 (11), 2463-2470, 2019 | 23 | 2019 |
Ultrahigh and high resolution structures and mutational analysis of monomeric Streptococcus pyogenes SpeB reveal a functional role for the glycine-rich C-terminal loop GE González-Páez, DW Wolan Journal of Biological Chemistry 287 (29), 24412-24426, 2012 | 22 | 2012 |
Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids CJ Vickers, GE González-Páez, KM Litwin, JC Umotoy, EA Coutsias, ... ACS Chemical Biology 9 (10), 2194-2198, 2014 | 21 | 2014 |
Synthesis of perfluoroalkyl-substituted oxindoles through organophotoredox-catalyzed perfluoroalkylation of N-arylacrylamides with perfluoroalkyl iodides Z Yang, A Tang Synlett 30 (09), 1061-1066, 2019 | 20 | 2019 |
Identification of the Plasmodium berghei resistance locus 9 linked to survival on chromosome 9 SER Bopp, E Rodrigo, GE González-Páez, M Frazer, SW Barnes, C Valim, ... Malaria journal 12, 1-12, 2013 | 19 | 2013 |
Small‐Molecule Procaspase Activators Identified Using Fluorescence Polarization CJ Vickers, GE González‐Páez, JC Umotoy, C Cayanan‐Garrett, ... ChemBioChem, 1419-1422, 2013 | 19 | 2013 |
Proteinases in excretory-secretory products of Toxocara canis second-stage larvae: zymography and modeling insights GE González-Páez, F Alba-Hurtado, CG García-Tovar, R Argüello-García BioMed Research International 2014, 2014 | 14 | 2014 |
Identification and Co-complex Structure of a New S. pyogenes SpeB Small Molecule Inhibitor AY Wang, GE González-Páez, DW Wolan Biochemistry 54 (28), 4365-4373, 2015 | 12 | 2015 |
Integrative x-ray structure and molecular modeling for the rationalization of procaspase-8 inhibitor potency and selectivity JH Xu, J Eberhardt, B Hill-Payne, GE González-Páez, JO Castellón, ... ACS chemical biology 15 (2), 575-586, 2020 | 6 | 2020 |
X-ray structure of an inactive zymogen clostripain-like protease from Parabacteroides distasonis GE González-Páez, EJ Roncase, DW Wolan Acta Crystallographica Section D: Structural Biology 75 (3), 325-332, 2019 | 6 | 2019 |