Johannes Zuber

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Christopher VakocCold Spring Harbor LaboratoryVerified email at cshl.edu
Junwei ShiUniversity of PennsylvaniaVerified email at upenn.edu
Gregory HannonCRUK, Cambridge University, New York Genome Center, Cold Spring Harbor LaboratoryVerified email at cruk.cam.ac.uk
Lukas DowAssociate Professor, Meyer Cancer Center, Weill Cornell MedicineVerified email at med.cornell.edu
Christof FellmannAssistant Adj Professor, UC San Francisco & Affiliate Investigator, Gladstone InstitutesVerified email at gladstone.ucsf.edu
Eric WangThe Jackson LaboratoryVerified email at jax.org
Stefan L AmeresMax Perutz Labs, University of ViennaVerified email at univie.ac.at
Ross DickinsAssociate Professor, Monash University (Australian Centre for Blood Diseases)Verified email at monash.edu
Jan-Michael PetersResearch Institute of Molecular Pathology (IMP)Verified email at imp.ac.at
Josef PenningerLife Sciences Institute, University of British Columbia / IMBA Institut für MolekulareVerified email at imba.oeaw.ac.at
Sumit DeswalAstraZeneca ABVerified email at astrazeneca.com
Philipp RathertInstitute of Biochemistry and Technical Biochemistry, University of StuttgartVerified email at ibtb.uni-stuttgart.de
Ulrich EllingIMBAVerified email at imba.oeaw.ac.at
Anna C ObenaufResearch Institute of Molecular PathologyVerified email at imp.ac.at
Juergen KnoblichInstitute of Molecular Biotechnology, ViennaVerified email at imba.oeaw.ac.at
Giulio Superti-FurgaScientific Director, CeMM Research Center for Molecular Medicine of the Austrian Academy ofVerified email at cemm.oeaw.ac.at
Alexander StarkResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, AustriaVerified email at imp.ac.at
Wen Xuethe RNA Therapeutics Institute at the University of Massachusetts Medical SchoolVerified email at umassmed.edu
Hans-Guido WendelMemorial Sloan Kettering Cancer CenterVerified email at mskcc.org

Johannes Zuber

Group Leader - IMP (Research Institute of Molecular Pathology), Vienna, Austria

Verified email at imp.ac.at - Homepage

cancer leukemia functional genomics RNAi CRISPR


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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia J Zuber, J Shi, E Wang, AR Rappaport, H Herrmann, EA Sison, D Magoon, ... Nature 478 (7370), 524-528, 2011	2093	2011
Senescence-associated reprogramming promotes cancer stemness M Milanovic, DNY Fan, D Belenki, JHM Däbritz, Z Zhao, Y Yu, JR Dörr, ... Nature 553 (7686), 96-100, 2018	865	2018
Cancer stem cell definitions and terminology: the devil is in the details P Valent, D Bonnet, R De Maria, T Lapidot, M Copland, JV Melo, ... Nature Reviews Cancer 12 (11), 767-775, 2012	808	2012
Toward understanding and exploiting tumor heterogeneity AA Alizadeh, V Aranda, A Bardelli, C Blanpain, C Bock, C Borowski, ... Nature medicine 21 (8), 846-853, 2015	770	2015
An optimized microRNA backbone for effective single-copy RNAi C Fellmann, T Hoffmann, V Sridhar, B Hopfgartner, M Muhar, M Roth, ... Cell reports 5 (6), 1704-1713, 2013	727	2013
Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins G Wutz, C Várnai, K Nagasaka, DA Cisneros, RR Stocsits, W Tang, ... The EMBO journal 36 (24), 3573-3599, 2017	681	2017
Human blood vessel organoids as a model of diabetic vasculopathy RA Wimmer, A Leopoldi, M Aichinger, N Wick, B Hantusch, ... Nature 565 (7740), 505-510, 2019	588	2019
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer L Zender, W Xue, J Zuber, CP Semighini, A Krasnitz, B Ma, P Zender, ... Cell 135 (5), 852-864, 2008	501	2008
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition P Rathert, M Roth, T Neumann, F Muerdter, JS Roe, M Muhar, S Deswal, ... Nature 525 (7570), 543-547, 2015	490	2015
Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation J Shi, WA Whyte, CJ Zepeda-Mendoza, JP Milazzo, C Shen, JS Roe, ... Genes & development 27 (24), 2648-2662, 2013	472	2013
Thiol-linked alkylation of RNA to assess expression dynamics VA Herzog, B Reichholf, T Neumann, P Rescheneder, P Bhat, TR Burkard, ... Nature methods 14 (12), 1198-1204, 2017	461	2017
Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia SP Glaser, EF Lee, E Trounson, P Bouillet, A Wei, WD Fairlie, DJ Izon, ... Genes & development 26 (2), 120-125, 2012	457	2012
Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia KJ Mavrakis, AL Wolfe, E Oricchio, T Palomero, K De Keersmaecker, ... Nature cell biology 12 (4), 372-379, 2010	416	2010
A genome-wide survey of RAS transformation targets J Zuber, OI Tchernitsa, B Hinzmann, AC Schmitz, M Grips, M Hellriegel, ... Nature genetics 24 (2), 144-152, 2000	365	2000
A rapid and scalable system for studying gene function in mice using conditional RNA interference PK Premsrirut, LE Dow, SY Kim, M Camiolo, CD Malone, C Miething, ... Cell 145 (1), 145-158, 2011	351	2011
Necroptosis microenvironment directs lineage commitment in liver cancer M Seehawer, F Heinzmann, L D’artista, J Harbig, PF Roux, L Hoenicke, ... Nature 562 (7725), 69-75, 2018	347	2018
MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia C Chen, Y Liu, AR Rappaport, T Kitzing, N Schultz, Z Zhao, AS Shroff, ... Cancer cell 25 (5), 652-665, 2014	336	2014
Mouse models of human AML accurately predict chemotherapy response J Zuber, I Radtke, TS Pardee, Z Zhao, AR Rappaport, W Luo, ... Genes & development 23 (7), 877-889, 2009	323	2009
Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi J Zuber, K McJunkin, C Fellmann, LE Dow, MJ Taylor, GJ Hannon, ... Nature biotechnology 29 (1), 79-83, 2011	311	2011
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis M Muhar, A Ebert, T Neumann, C Umkehrer, J Jude, C Wieshofer, ... Science 360 (6390), 800-805, 2018	305	2018

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