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Muhammet Fatih Gulen
Muhammet Fatih Gulen
PhD
Verified email at epfl.ch
Title
Cited by
Cited by
Year
Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
S Glück, B Guey, MF Gulen, K Wolter, TW Kang, NA Schmacke, ...
Nature cell biology 19 (9), 1061-1070, 2017
8402017
Interleukin-23-independent IL-17 production regulates intestinal epithelial permeability
JS Lee, CM Tato, B Joyce-Shaikh, MF Gulen, C Cayatte, Y Chen, ...
Immunity 43 (4), 727-738, 2015
6642015
The adaptor Act1 is required for interleukin 17–dependent signaling associated with autoimmune and inflammatory disease
Y Qian, C Liu, J Hartupee, CZ Altuntas, MF Gulen, D Jane-Wit, J Xiao, ...
Nature immunology 8 (3), 247-256, 2007
6522007
Targeting STING with covalent small-molecule inhibitors
SM Haag, MF *Gulen, L Reymond, A Gibelin, L Abrami, A Decout, ...
Nature 559 (7713), 269-273, 2018
6452018
Mycobacterium tuberculosis differentially activates cGAS-and inflammasome-dependent intracellular immune responses through ESX-1
R Wassermann, MF *Gulen, C Sala, SG Perin, Y Lou, J Rybniker, ...
Cell host & microbe 17 (6), 799-810, 2015
3782015
The Toll–interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis
H Xiao, MF *Gulen, J Qin, J Yao, K Bulek, D Kish, CZ Altuntas, D Wald, ...
Immunity 26 (4), 461-475, 2007
3682007
Signalling strength determines proapoptotic functions of STING
MF Gulen, U Koch, SM Haag, F Schuler, L Apetoh, A Villunger, F Radtke, ...
Nature communications 8 (1), 427, 2017
3512017
Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis
Z Kang, CZ Altuntas, MF Gulen, C Liu, N Giltiay, H Qin, L Liu, W Qian, ...
Immunity 32 (3), 414-425, 2010
3232010
The cGAS–STING pathway drives type I IFN immunopathology in COVID-19
JD Domizio, MF *Gulen, F Saidoune, VV Thacker, A Yatim, K Sharma, ...
Nature 603 (7899), 145-151, 2022
2772022
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation
MF Gulen, Z Kang, K Bulek, W Youzhong, TW Kim, Y Chen, CZ Altuntas, ...
Immunity 32 (1), 54-66, 2010
2242010
The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response
K Bulek, S Swaidani, J Qin, Y Lu, MF Gulen, T Herjan, B Min, ...
The Journal of Immunology 182 (5), 2601-2609, 2009
2182009
The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation
K Bulek, C Liu, S Swaidani, L Wang, RC Page, MF Gulen, T Herjan, ...
Nature immunology 12 (9), 844-852, 2011
2172011
T cell–intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis
BN Martin, C Wang, C Zhang, Z Kang, MF Gulen, JA Zepp, J Zhao, G Bian, ...
Nature immunology 17 (5), 583-592, 2016
1522016
Interleukin-1 (IL-1)-induced TAK1-dependent versus MEKK3-dependent NFκB activation pathways bifurcate at IL-1 receptor-associated kinase modification
J Yao, TW Kim, J Qin, Z Jiang, Y Qian, H Xiao, Y Lu, W Qian, MF Gulen, ...
Journal of Biological Chemistry 282 (9), 6075-6089, 2007
1282007
IKKα negatively regulates ASC-dependent inflammasome activation
BN Martin, C Wang, J Willette-Brown, T Herjan, MF Gulen, H Zhou, ...
Nature communications 5 (1), 4977, 2014
1142014
Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance
MF Gulen, K Bulek, H Xiao, M Yu, J Gao, L Sun, E Beurel, ...
Immunity 37 (5), 800-812, 2012
952012
IL-17-induced Act1-mediated signaling is critical for cuprizone-induced demyelination
Z Kang, L Liu, R Spangler, C Spear, C Wang, MF Gulen, M Veenstra, ...
Journal of Neuroscience 32 (24), 8284-8292, 2012
922012
SIGIRR, a negative regulator of TLR/IL-1R signalling promotes Microbiota dependent resistance to colonization by enteric bacterial pathogens
HP Sham, EYS Yu, MF Gulen, G Bhinder, M Stahl, JM Chan, L Brewster, ...
PLoS pathogens 9 (8), e1003539, 2013
912013
Cutting edge: TNF receptor-associated factor 4 restricts IL-17–mediated pathology and signaling processes
JA Zepp, C Liu, W Qian, L Wu, MF Gulen, Z Kang, X Li
The Journal of Immunology 189 (1), 33-37, 2012
902012
IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease
KA Staschke, S Dong, J Saha, J Zhao, NA Brooks, DL Hepburn, J Xia, ...
The Journal of Immunology 183 (1), 568-577, 2009
852009
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