Carles Martínez-Romero, M.Sc. Ph.D.
Carles Martínez-Romero, M.Sc. Ph.D.
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Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A
KM White, R Rosales, S Yildiz, T Kehrer, L Miorin, E Moreno, S Jangra, ...
Science 371 (6532), 926-931, 2021
Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs
J Kouznetsova, W Sun, C Martínez-Romero, G Tawa, P Shinn, CZ Chen, ...
Emerging microbes & infections 3 (1), 1-7, 2014
Virus-induced senescence is a driver and therapeutic target in COVID-19
S Lee, Y Yu, J Trimpert, F Benthani, M Mairhofer, P Richter-Pechanska, ...
Nature 599 (7884), 283-289, 2021
The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon
M Laurent-Rolle, J Morrison, R Rajsbaum, JML Macleod, G Pisanelli, ...
Cell host & microbe 16 (3), 314-327, 2014
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response
R Rajsbaum, GA Versteeg, S Schmid, AM Maestre, A Belicha-Villanueva, ...
Immunity 40 (6), 880-895, 2014
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry
S Yang, M Xu, EM Lee, K Gorshkov, SA Shiryaev, S He, W Sun, ...
Cell discovery 4 (1), 31, 2018
The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera
R Rathnasinghe, S Jangra, A Cupic, C Martínez-Romero, LCF Mulder, ...
MedRxiv, 2021
Synergistic drug combination effectively blocks Ebola virus infection
W Sun, S He, C Martínez-Romero, J Kouznetsova, G Tawa, M Xu, P Shinn, ...
Antiviral research 137, 165-172, 2017
N-glycolylneuraminic acid as a receptor for influenza A viruses
F Broszeit, N Tzarum, X Zhu, N Nemanichvili, D Eggink, T Leenders, Z Li, ...
Cell reports 27 (11), 3284-3294. e6, 2019
Innate immune response to influenza virus at single-cell resolution in human epithelial cells revealed paracrine induction of interferon lambda 1
I Ramos, G Smith, F Ruf-Zamojski, C Martínez-Romero, M Fribourg, ...
Journal of virology 93 (20), 10.1128/jvi. 00559-19, 2019
Antiviral role of IFITM proteins in African swine fever virus infection
R Muñoz-Moreno, MÁ Cuesta-Geijo, C Martínez-Romero, L Barrado-Gil, ...
PloS one 11 (4), e0154366, 2016
The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma
C Martínez‐Romero, I Rooman, A Skoudy, C Guerra, X Molero, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009
Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions
RP de Vries, E de Vries, C Martínez-Romero, R McBride, ...
Journal of virology 87 (24), 13868-13877, 2013
Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death
BM Hartmann, RA Albrecht, E Zaslavsky, G Nudelman, H Pincas, ...
Nature communications 8 (1), 1931, 2017
Hybrid gene origination creates human-virus chimeric proteins during infection
JSY Ho, M Angel, Y Ma, E Sloan, G Wang, C Martinez-Romero, ...
Cell 181 (7), 1502-1517. e23, 2020
The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells
A Bosch, K Panoutsopoulou, JM Corominas, R Gimeno, G Moreno-Bueno, ...
Oncotarget 5 (8), 2065, 2014
ISG15 is counteracted by vaccinia virus E3 protein and controls the proinflammatory response against viral infection
B Eduardo-Correia, C Martínez-Romero, A García-Sastre, S Guerra
Journal of virology 88 (4), 2312-2318, 2014
Computer-aided discovery and characterization of novel Ebola virus inhibitors
SJ Capuzzi, W Sun, EN Muratov, C Martínez-Romero, S He, W Zhu, H Li, ...
Journal of medicinal chemistry 61 (8), 3582-3594, 2018
Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera
R Rathnasinghe, S Jangra, C Ye, A Cupic, G Singh, C Martínez-Romero, ...
Nature Communications 13 (1), 3921, 2022
Modeling SARS-CoV-2: comparative pathology in rhesus macaque and Golden Syrian hamster models
S Choudhary, I Kanevsky, S Yildiz, RS Sellers, KA Swanson, T Franks, ...
Toxicologic pathology 50 (3), 280-293, 2022
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