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| A unique gene regulatory network resets the human germline epigenome for development WWC Tang, S Dietmann, N Irie, HG Leitch, VI Floros, CR Bradshaw, ... Cell 161 (6), 1453-1467, 2015 | 632 | 2015 |
| Naive pluripotency is associated with global DNA hypomethylation HG Leitch, KR McEwen, A Turp, V Encheva, T Carroll, N Grabole, ... Nature structural & molecular biology 20 (3), 311-316, 2013 | 548 | 2013 |
| Hallmarks of pluripotency A De Los Angeles, F Ferrari, R Xi, Y Fujiwara, N Benvenisty, H Deng, ... Nature 525 (7570), 469-478, 2015 | 454 | 2015 |
| Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte PWS Hill, HG Leitch, CE Requena, Z Sun, R Amouroux, M Roman-Trufero, ... Nature 555 (7696), 392-396, 2018 | 211 | 2018 |
| Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation N Grabole, J Tischler, JA Hackett, S Kim, F Tang, HG Leitch, ... EMBO reports 14 (7), 629-637, 2013 | 175 | 2013 |
| Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst GC Le Bin, S Muñoz-Descalzo, A Kurowski, H Leitch, X Lou, W Mansfield, ... Development 141 (5), 1001-1010, 2014 | 173 | 2014 |
| Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state HG Leitch, K Blair, W Mansfield, H Ayetey, P Humphreys, J Nichols, ... Development 137 (14), 2279-2287, 2010 | 163 | 2010 |
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| Primordial germ-cell development and epigenetic reprogramming in mammals. HG Leitch, WW Tang, MA Surani Current topics in developmental biology 104, 149-187, 2013 | 135 | 2013 |
| Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion FM Piccolo, H Bagci, KE Brown, D Landeira, J Soza-Ried, A Feytout, ... Molecular cell 49 (6), 1023-1033, 2013 | 108 | 2013 |
| Defined conditions for propagation and manipulation of mouse embryonic stem cells C Mulas, T Kalkan, F von Meyenn, HG Leitch, J Nichols, A Smith Development 146 (6), dev173146, 2019 | 91 | 2019 |
| Reconstitution of the oocyte transcriptional network with transcription factors N Hamazaki, H Kyogoku, H Araki, F Miura, C Horikawa, N Hamada, ... Nature 589 (7841), 264-269, 2021 | 84 | 2021 |
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| The mammalian germline as a pluripotency cycle HG Leitch, A Smith Development 140 (12), 2495-2501, 2013 | 75 | 2013 |
| Esrrb complementation rescues development of Nanog-null germ cells M Zhang, HG Leitch, WWC Tang, N Festuccia, E Hall-Ponsele, J Nichols, ... Cell reports 22 (2), 332-339, 2018 | 42 | 2018 |
| SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA N Cvetesic, HG Leitch, M Borkowska, F Müller, P Carninci, P Hajkova, ... Genome Research 28 (12), 1943-1956, 2018 | 38 | 2018 |
| The impact of culture on epigenetic properties of pluripotent stem cells and pre-implantation embryos KR McEwen, HG Leitch, R Amouroux, P Hajkova Biochemical Society Transactions 41 (3), 711-719, 2013 | 35 | 2013 |
| Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells K Blair, HG Leitch, W Mansfield, CÉ Dumeau, P Humphreys, AG Smith Biology Open 1 (1), 58-65, 2011 | 32 | 2011 |
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Petra HajkovaMRC London Institute of Medical SciencesVerified email at lms.mrc.ac.uk
