APOBEC3B is an enzymatic source of mutation in breast cancer MB Burns, L Lackey, MA Carpenter, A Rathore, AM Land, B Leonard, ... Nature 494 (7437), 366-370, 2013 | 884 | 2013 |
Evidence for APOBEC3B mutagenesis in multiple human cancers MB Burns, NA Temiz, RS Harris Nature genetics 45 (9), 977-983, 2013 | 792 | 2013 |
A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis BS Moriarity, GM Otto, EP Rahrmann, SK Rathe, NK Wolf, MT Weg, ... Nature genetics 47 (6), 615-624, 2015 | 256 | 2015 |
Conformational changes in HIV-1 reverse transcriptase induced by nonnucleoside reverse transcriptase inhibitor binding N Sluis-Cremer, NA Temiz, I Bahar Current HIV research 2 (4), 323-332, 2004 | 240 | 2004 |
The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer EK Law, AM Sieuwerts, K LaPara, B Leonard, GJ Starrett, AM Molan, ... Science advances 2 (10), e1601737, 2016 | 208 | 2016 |
Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B VC Vieira, B Leonard, EA White, GJ Starrett, NA Temiz, LD Lorenz, D Lee, ... MBio 5 (6), 10.1128/mbio. 02234-14, 2014 | 185 | 2014 |
APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma B Leonard, SN Hart, MB Burns, MA Carpenter, NA Temiz, A Rathore, ... Cancer research 73 (24), 7222-7231, 2013 | 181 | 2013 |
The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis GJ Starrett, EM Luengas, JL McCann, D Ebrahimi, NA Temiz, RP Love, ... Nature communications 7 (1), 12918, 2016 | 166 | 2016 |
Non-B DB v2. 0: a database of predicted non-B DNA-forming motifs and its associated tools RZ Cer, DE Donohue, US Mudunuri, NA Temiz, MA Loss, NJ Starner, ... Nucleic acids research 41 (D1), D94-D100, 2012 | 153 | 2012 |
APOBEC3A catalyzes mutation and drives carcinogenesis in vivo EK Law, R Levin-Klein, MC Jarvis, H Kim, PP Argyris, MA Carpenter, ... Journal of Experimental Medicine 217 (12), 2020 | 113 | 2020 |
Inhibitor binding alters the directions of domain motions in HIV‐1 reverse transcriptase NA Temiz, I Bahar Proteins: Structure, Function, and Bioinformatics 49 (1), 61-70, 2002 | 113 | 2002 |
Escherichia coli adenylate kinase dynamics: Comparison of elastic network model modes with mode‐coupling 15N‐NMR relaxation data NA Temiz, E Meirovitch, I Bahar PROTEINS: Structure, Function, and Bioinformatics 57 (3), 468-480, 2004 | 106 | 2004 |
Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression, and survival in osteosarcoma MC Scott, NA Temiz, AE Sarver, RS LaRue, SK Rathe, J Varshney, ... Cancer research 78 (2), 326-337, 2018 | 99 | 2018 |
The role of methylation in the intrinsic dynamics of B-and Z-DNA NA Temiz, DE Donohue, A Bacolla, BT Luke, JR Collins PLoS One 7 (4), e35558, 2012 | 77 | 2012 |
Mutation signatures including APOBEC in cancer cell lines MC Jarvis, D Ebrahimi, NA Temiz, RS Harris JNCI cancer spectrum 2 (1), pky002, 2018 | 54 | 2018 |
Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors BR Tschida, NA Temiz, TP Kuka, LA Lee, JD Riordan, CA Tierrablanca, ... Cancer research 77 (23), 6576-6588, 2017 | 39 | 2017 |
Mutation processes in 293-based clones overexpressing the DNA cytosine deaminase APOBEC3B MK Akre, GJ Starrett, JS Quist, NA Temiz, MA Carpenter, ANJ Tutt, ... PloS one 11 (5), e0155391, 2016 | 38 | 2016 |
RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens NA Temiz, BS Moriarity, NK Wolf, JD Riordan, AJ Dupuy, ... Genome research 26 (1), 119-129, 2016 | 37 | 2016 |
Guanine holes are prominent targets for mutation in cancer and inherited disease A Bacolla, NA Temiz, M Yi, J Ivanic, RZ Cer, DE Donohue, EV Ball, ... PLoS genetics 9 (9), e1003816, 2013 | 36 | 2013 |
Searching for non‐B DNA‐forming motifs using nBMST (non‐B DNA motif search tool) RZ Cer, KH Bruce, DE Donohue, NA Temiz, US Mudunuri, M Yi, ... Current protocols in human genetics 73 (1), 18.7. 1-18.7. 22, 2012 | 33 | 2012 |