| Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling JJ Fros, WJ Liu, NA Prow, C Geertsema, M Ligtenberg, ... Journal of virology 84 (20), 10877-10887, 2010 | 290 | 2010 |
| Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors J Boshuizen, LA Koopman, O Krijgsman, A Shahrabi, EG van den Heuvel, ... Nature medicine 24 (2), 203-212, 2018 | 203 | 2018 |
| Coexpressed catalase protects chimeric antigen receptor–redirected T cells as well as bystander cells from oxidative stress–induced loss of antitumor activity MA Ligtenberg, D Mougiakakos, M Mukhopadhyay, K Witt, A Lladser, ... The Journal of Immunology 196 (2), 759-766, 2016 | 193 | 2016 |
| Augmenting immunotherapy impact by lowering tumor TNF cytotoxicity threshold DW Vredevoogd, T Kuilman, MA Ligtenberg, J Boshuizen, KE Stecker, ... Cell 178 (3), 585-599. e15, 2019 | 181 | 2019 |
| Genetic engineering of human NK cells to express CXCR2 improves migration to renal cell carcinoma V Kremer, MA Ligtenberg, R Zendehdel, C Seitz, A Duivenvoorden, ... Journal for immunotherapy of cancer 5, 1-13, 2017 | 135 | 2017 |
| Reversal of pre-existing NGFR-driven tumor and immune therapy resistance J Boshuizen, DW Vredevoogd, O Krijgsman, MA Ligtenberg, ... Nature communications 11 (1), 3946, 2020 | 77 | 2020 |
| DAI (DLM-1/ZBP1) as a genetic adjuvant for DNA vaccines that promotes effective antitumor CTL immunity A Lladser, D Mougiakakos, H Tufvesson, MA Ligtenberg, AFG Quest, ... Molecular Therapy 19 (3), 594-601, 2011 | 65 | 2011 |
| Self-delivering RNAi targeting PD-1 improves tumor-specific T cell functionality for adoptive cell therapy of malignant melanoma MA Ligtenberg, YP de Coaña, T Shmushkovich, Y Yoshimoto, I Truxova, ... Molecular Therapy 26 (6), 1482-1493, 2018 | 41 | 2018 |
| Harnessing DNA-induced immune responses for improving cancer vaccines AA Herrada, N Rojas-Colonelli, P González-Figueroa, J Roco, C Oyarce, ... Human vaccines & immunotherapeutics 8 (11), 1682-1693, 2012 | 36 | 2012 |
| Cooperative targeting of immunotherapy-resistant melanoma and lung cancer by an AXL-targeting antibody–drug conjugate and immune checkpoint blockade J Boshuizen, N Pencheva, O Krijgsman, DDE Altimari, PG Castro, ... Cancer research 81 (7), 1775-1787, 2021 | 30 | 2021 |
| Cripto-1 plasmid DNA vaccination targets metastasis and cancer stem cells in murine mammary carcinoma K Witt, MA Ligtenberg, L Conti, S Lanzardo, R Ruiu, T Wallmann, ... Cancer immunology research 6 (11), 1417-1425, 2018 | 30 | 2018 |
| Cancer neoepitopes for immunotherapy: discordance between tumor-infiltrating T cell reactivity and tumor MHC peptidome display SL Wickström, T Lövgren, M Volkmar, B Reinhold, JS Duke-Cohan, ... Frontiers in immunology 10, 2766, 2019 | 28 | 2019 |
| Cripto-1 vaccination elicits protective immunity against metastatic melanoma MA Ligtenberg, K Witt, F Galvez-Cancino, A Sette, A Lundqvist, A Lladser, ... Oncoimmunology 5 (5), e1128613, 2016 | 28 | 2016 |
| Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling G Apriamashvili, DW Vredevoogd, O Krijgsman, OB Bleijerveld, ... Nature communications 13 (1), 1923, 2022 | 25 | 2022 |
| NF-κB activation during intradermal DNA vaccination is essential for eliciting tumor protective antigen-specific CTL responses MA Ligtenberg, N Rojas-Colonelli, R Kiessling, A Lladser Human Vaccines & Immunotherapeutics 9 (10), 2189-2195, 2013 | 23 | 2013 |
| NF-κB activation during intradermal DNA vaccination is essential for eliciting tumor protective antigen-specific CTL responses MA Ligtenberg, N Rojas-Colonelli, R Kiessling, A Lladser Human Vaccines & Immunotherapeutics 9 (10), 2189-2195, 2013 | 23 | 2013 |
| RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells Z Zhang, X Kong, MA Ligtenberg, SE Van Hal-van Veen, NL Visser, ... Cell Reports Medicine 3 (6), 2022 | 21 | 2022 |
| Augmenting immunotherapy impact by lowering tumor TNF cytotoxicity threshold DW Vredevoogd, T Kuilman, MA Ligtenberg, J Boshuizen, KE Stecker, ... Cell 180 (2), 404-405, 2020 | 20 | 2020 |
| Methylcholanthrene-induced sarcomas develop independently from NOX2-derived ROS MA Ligtenberg, Ö Çınar, R Holmdahl, D Mougiakakos, R Kiessling PLoS One 10 (6), e0129786, 2015 | 16 | 2015 |
| Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma W Theelen, O Krijgsman, K Monkhorst, T Kuilman, D Peters, ... Journal of translational medicine 18, 1-12, 2020 | 10 | 2020 |
