Alexander (Sasha) Gusev
Alexander (Sasha) Gusev
Dana-Farber Cancer Institute
Verified email at dfci.harvard.edu - Homepage
Title
Cited by
Cited by
Year
An atlas of genetic correlations across human diseases and traits
B Bulik-Sullivan, HK Finucane, V Anttila, A Gusev, FR Day, PR Loh, ...
Nature genetics 47 (11), 1236-1241, 2015
2181*2015
Partitioning heritability by functional annotation using genome-wide association summary statistics
HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ...
Nature genetics 47 (11), 1228-1235, 2015
13632015
Integrative approaches for large-scale transcriptome-wide association studies
A Gusev, A Ko, H Shi, G Bhatia, W Chung, B Penninx, R Jansen, E Geus, ...
Nature Genetics 48 (3), 245–252, 2016
9882016
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
The american journal of human genetics 97 (4), 576-592, 2015
7822015
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ...
The American Journal of Human Genetics 95 (5), 535-552, 2014
5402014
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
HK Finucane, YA Reshef, V Anttila, K Slowikowski, A Gusev, A Byrnes, ...
Nature genetics 50 (4), 621-629, 2018
4612018
Whole population, genome-wide mapping of hidden relatedness
A Gusev, JK Lowe, M Stoffel, MJ Daly, D Altshuler, JL Breslow, ...
Genome research 19 (2), 318-326, 2009
4512009
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis
PR Loh, G Bhatia, A Gusev, HK Finucane, BK Bulik-Sullivan, SJ Pollack, ...
Nature genetics 47 (12), 1385-1392, 2015
3622015
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
A Gusev, N Mancuso, H Won, M Kousi, HK Finucane, Y Reshef, L Song, ...
Nature genetics 50 (4), 538-548, 2018
2482018
Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection
S Gazal, HK Finucane, NA Furlotte, PR Loh, PF Palamara, X Liu, ...
Nature genetics 49 (10), 1421-1427, 2017
2302017
Integrating gene expression with summary association statistics to identify genes associated with 30 complex traits
N Mancuso, H Shi, P Goddard, G Kichaev, A Gusev, B Pasaniuc
The American Journal of Human Genetics 100 (3), 473-487, 2017
1882017
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
B Pasaniuc, N Zaitlen, H Shi, G Bhatia, A Gusev, J Pickrell, J Hirschhorn, ...
Bioinformatics 30 (20), 2906-2914, 2014
1692014
Quantifying missing heritability at known GWAS loci
A Gusev, G Bhatia, N Zaitlen, BJ Vilhjalmsson, D Diogo, EA Stahl, ...
PLoS genetics 9 (12), e1003993, 2013
1302013
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
L Wu, W Shi, J Long, X Guo, K Michailidou, J Beesley, MK Bolla, XO Shu, ...
Nature genetics 50 (7), 968-978, 2018
1262018
Probabilistic fine-mapping of transcriptome-wide association studies
N Mancuso, MK Freund, R Johnson, H Shi, G Kichaev, A Gusev, ...
Nature genetics 51 (4), 675-682, 2019
1232019
The architecture of long-range haplotypes shared within and across populations
A Gusev, PF Palamara, G Aponte, Z Zhuang, A Darvasi, P Gregersen, ...
Molecular biology and evolution 29 (2), 473-486, 2012
972012
Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits
F Hormozdiari, S Gazal, B Van De Geijn, HK Finucane, CJT Ju, PR Loh, ...
Nature genetics 50 (7), 1041-1047, 2018
922018
Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study. Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
Am J Hum Genet 97 (4), 576-592, 2015
832015
Quantifying genetic effects on disease mediated by assayed gene expression levels
DW Yao, LJ O’Connor, AL Price, A Gusev
Nature Genetics 52 (6), 626-633, 2020
782020
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
N Mancuso, S Gayther, A Gusev, W Zheng, KL Penney, Z Kote-Jarai, ...
Nature communications 9 (1), 1-11, 2018
712018
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Articles 1–20