Hung-Jen Chen

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Menno de WintherProfessor of Vascular Immune Cell BiologyVerified email at amsterdamumc.nl
Annette Elise NeeleAmsterdam UMCVerified email at amsterdamumc.nl
Marten HoeksemaGroup Leader, Amsterdam UMC, University of Amsterdam, the NetherlandsVerified email at amsterdamumc.nl
saskia van der veldenphd at SanquinVerified email at sanquin.nl
Jan Van den BosscheAssociate Professor, Amsterdam UMCVerified email at amsterdamumc.nl
Jeroen BaardmanAmsterdam UMC - University of AmsterdamVerified email at amsterdamumc.nl
Wouter de JongeProf of exp Gastroenterology, Amsterdam UMCVerified email at amsterdamumc.nl
Jeroen den DunnenAssociate Professor, AMC AmsterdamVerified email at amsterdamumc.nl
Andrew Li YimAmsterdam University Medical Center, University of Amsterdam and OmiQuantVerified email at amsterdamumc.nl
Enrico FerreroAutoimmunity Transplantation and Inflammation Bioinformatics, NovartisVerified email at novartis.com
Esther LutgensMayo Clinic, Rochester, MN, USAVerified email at mayo.edu
Lisa WillemsenLa Jolla Institute for ImmunologyVerified email at lji.org
Willianne HoepelAmsterdam UMCVerified email at amsterdamumc.nl
Jeffrey KroonAcademic Medical Center, AmsterdamVerified email at amc.uva.nl
Sander W. TasAmsterdam UMC, location Academic Medical Center/University of AmsterdamVerified email at amsterdamumc.nl
Marcel MannensHoogleraar genoomdiagnostiek in het bijzonder epigenetica van ziektenVerified email at amsterdamumc.nl
Timo van den BergByondis BVVerified email at byondis.com
Chiara E. GeyerAmsterdam UMCVerified email at amsterdamumc.nl
Gestur VidarssonProfessor Immunoglobulin biotherapeutics, Sanquin Research, and Dept. Pharmaceutics, UtrechtVerified email at sanquin.nl
Steven de TaeyePost-doc, Amsterdam UMCVerified email at amsterdamumc.nl

Hung-Jen Chen

Other namesOliver Chen

Amsterdam University Medical Centers

Verified email at amsterdamumc.nl - Homepage

macrophage immunometabolism epigenetics infectious diseases rheumatic diseases


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Mitochondrial dysfunction prevents repolarization of inflammatory macrophages J Van den Bossche, J Baardman, NA Otto, S van der Velden, AE Neele, ... Cell reports 17 (3), 684-696, 2016	696	2016
Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity MD Larsen, EL de Graaf, ME Sonneveld, HR Plomp, J Nouta, W Hoepel, ... Science 371 (6532), eabc8378, 2021	309	2021
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages W Hoepel, HJ Chen, CE Geyer, S Allahverdiyeva, XD Manz, SW de Taeye, ... Science translational medicine 13 (596), eabf8654, 2021	172	2021
Type-I interferons in atherosclerosis HJ Chen, SW Tas, MPJ de Winther Journal of Experimental Medicine 217 (1), 2020	78	2020
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses W Hoepel, HJ Chen, S Allahverdiyeva, X Manz, J Aman, ... BioRxiv, 2020.07. 13.190140, 2020	60	2020
Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo HJ Chen, AYF Li Yim, GR Griffith, WJ de Jonge, MMAM Mannens, ... Frontiers in immunology 10, 2887, 2019	34	2019
Myeloid Kdm6b deficiency results in advanced atherosclerosis AE Neele, MJJ Gijbels, S van der Velden, MA Hoeksema, ... Atherosclerosis 275, 156-165, 2018	26	2018
The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees J Van Coillie, T Pongracz, J Rahmöller, HJ Chen, CE Geyer, ... eBioMedicine 87, 104408, 2023	21	2023
Targeting epigenetics as atherosclerosis treatment: an updated view AE Neele, L Willemsen, HJ Chen, KE Dzobo, MPJ de Winther Current opinion in lipidology 31 (6), 324-330, 2020	16	2020
Myeloid Ezh2 deficiency limits atherosclerosis development AE Neele, HJ Chen, MJJ Gijbels, S Van der Velden, MA Hoeksema, ... Frontiers in immunology 11, 594603, 2021	14	2021
Monocyte and macrophage lipid accumulation results in down-regulated type-I interferon responses L Willemsen, HJ Chen, CPAA van Roomen, GR Griffith, R Siebeler, ... Frontiers in Cardiovascular Medicine 9, 829877, 2022	11	2022
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages. Sci. Transl. Med. 13, eabf8654 W Hoepel, HJ Chen, CE Geyer, S Allahverdiyeva, XD Manz, SW de Taeye, ...	8	2021
C-Reactive Protein Controls IL-23 Production by Human Monocytes CE Geyer, M Newling, L Sritharan, GR Griffith, HJ Chen, DLP Baeten, ... International journal of molecular sciences 22 (21), 11638, 2021	7	2021
Meta-analysis of HJ Chen, AYF Li Yim, GR Griffith, WJ de Jonge, M Mannens, E Ferrero Education Tech Research Development, 68, 1855-1873, 2020	7	2020
COVID-19, biobank study group MD Larsen, EL de Graaf, ME Sonneveld, HR Plomp, J Nouta, W Hoepel, ... Rispens, T, 2021	5	2021
IgA2 immune complexes selectively promote inflammation by human CD103⁺ dendritic cells L Mes, U Steffen, HJ Chen, J Veth, W Hoepel, GR Griffith, G Schett, ... Frontiers in Immunology 14, 1116435, 2023	4	2023
g. biobank study, Rispens T., den Dunnen J., Zaaijer HL, Wuhrer M., van der Schoot C. Ellen, Vidarsson G. Afucosylated IgG characterizes enveloped viral responses and … MD Larsen, EL de Graaf, ME Sonneveld, HR Plomp, J Nouta, W Hoepel, ... Science 371 (6532), 94, 2021	4	2021
DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability L Willemsen, KHM Prange, AE Neele, CPAA Van Roomen, M Gijbels, ... Cell Reports 41 (8), 2022	3	2022
Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19 CE Geyer, HJ Chen, AP Bye, XD Manz, D Guerra, TG Caniels, TPL Bijl, ... Life Science Alliance 6 (11), 2023	2	2023
Exploring the expression and potential function of follicle stimulating hormone receptor in extragonadal cells related to abdominal aortic aneurysm VN Tedjawirja, A Mieremet, KB Rombouts, C Yap, AE Neele, BH Northoff, ... Plos one 18 (5), e0285607, 2023		2023

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