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Jianjun Zhang
Jianjun Zhang
Professor, Dept. Thoracic/Head and Neck Medical Oncology, Dept. Genomic Medicine, MD
Verified email at mdanderson.org
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Cited by
Year
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma
F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ...
Cancer discovery 8 (7), 822-835, 2018
13252018
Local consolidative therapy vs. maintenance therapy or observation for patients with oligometastatic non–small-cell lung cancer: long-term results of a multi-institutional …
DR Gomez, C Tang, J Zhang, GR Blumenschein Jr, M Hernandez, JJ Lee, ...
Journal of Clinical Oncology 37 (18), 1558-1565, 2019
10992019
Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer without progression after first-line systemic …
DR Gomez, GR Blumenschein, JJ Lee, M Hernandez, R Ye, DR Camidge, ...
The lancet oncology 17 (12), 1672-1682, 2016
10612016
Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing
J Zhang, J Fujimoto, J Zhang, DC Wedge, X Song, J Zhang, S Seth, ...
Science 346 (6206), 256-259, 2014
10392014
Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic …
F Skoulidis, LA Byers, L Diao, VA Papadimitrakopoulou, P Tong, J Izzo, ...
Cancer discovery 5 (8), 860-877, 2015
8212015
Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial
T Cascone, WN William Jr, A Weissferdt, CH Leung, HY Lin, A Pataer, ...
Nature medicine 27 (3), 504-514, 2021
4922021
Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma
Y Zhou, D Yang, Q Yang, X Lv, W Huang, Z Zhou, Y Wang, Z Zhang, ...
Nature communications 11 (1), 6322, 2020
3672020
Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC
X Le, S Puri, MV Negrao, MB Nilsson, J Robichaux, T Boyle, JK Hicks, ...
Clinical Cancer Research 24 (24), 6195-6203, 2018
3532018
Single-cell analyses reveal increased intratumoral heterogeneity after the onset of therapy resistance in small-cell lung cancer
CA Stewart, CM Gay, Y Xi, S Sivajothi, V Sivakamasundari, J Fujimoto, ...
Nature cancer 1 (4), 423-436, 2020
3022020
MuSE: accounting for tumor heterogeneity using a sample-specific error model improves sensitivity and specificity in mutation calling from sequencing data
Y Fan, L Xi, DST Hughes, J Zhang, J Zhang, PA Futreal, DA Wheeler, ...
Genome biology 17, 1-11, 2016
2912016
Structure-based classification predicts drug response in EGFR-mutant NSCLC
JP Robichaux, X Le, RSK Vijayan, JK Hicks, S Heeke, YY Elamin, HY Lin, ...
Nature 597 (7878), 732-737, 2021
2852021
Molecular profiling reveals unique immune and metabolic features of melanoma brain metastases
GM Fischer, A Jalali, DA Kircher, WC Lee, JL McQuade, LE Haydu, ...
Cancer discovery 9 (5), 628-645, 2019
2792019
Diminished efficacy of programmed death-(ligand) 1 inhibition in STK11-and KEAP1-mutant lung adenocarcinoma is affected by KRAS mutation status
B Ricciuti, KC Arbour, JJ Lin, A Vajdi, N Vokes, L Hong, J Zhang, ...
Journal of Thoracic Oncology 17 (3), 399-410, 2022
2282022
Caspase-dependent and-independent activation of acid sphingomyelinase signaling
JA Rotolo, J Zhang, M Donepudi, H Lee, Z Fuks, R Kolesnick
Journal of Biological Chemistry 280 (28), 26425-26434, 2005
2102005
Neoadjuvant nivolumab (N) or nivolumab plus ipilimumab (NI) for resectable non-small cell lung cancer (NSCLC): Clinical and correlative results from the NEOSTAR study.
T Cascone, WN William, A Weissferdt, HY Lin, CH Leung, BW Carter, ...
Journal of Clinical Oncology 37 (15_suppl), 8504-8504, 2019
2082019
Response rates to single-agent chemotherapy after exposure to immune checkpoint inhibitors in advanced non-small cell lung cancer
G Schvartsman, SA Peng, G Bis, JJ Lee, MFK Benveniste, J Zhang, ...
Lung cancer 112, 90-95, 2017
2072017
Comprehensive T cell repertoire characterization of non-small cell lung cancer
A Reuben, J Zhang, SH Chiou, RM Gittelman, J Li, WC Lee, J Fujimoto, ...
Nature communications 11 (1), 603, 2020
1862020
TCR repertoire intratumor heterogeneity in localized lung adenocarcinomas: an association with predicted neoantigen heterogeneity and postsurgical recurrence
A Reuben, R Gittelman, J Gao, J Zhang, EC Yusko, CJ Wu, R Emerson, ...
Cancer discovery 7 (10), 1088-1097, 2017
1862017
ATM regulates target switching to escalating doses of radiation in the intestines
HJ Ch'ang, JG Maj, F Paris, HR Xing, J Zhang, JP Truman, ...
Nature medicine 11 (5), 484-490, 2005
1712005
Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer
MV Negrao, F Skoulidis, M Montesion, K Schulze, I Bara, V Shen, H Xu, ...
Journal for immunotherapy of cancer 9 (8), 2021
1672021
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