Sensitive red protein calcium indicators for imaging neural activity H Dana, B Mohar, Y Sun, S Narayan, A Gordus, JP Hasseman, ... Elife 5, e12727, 2016 | 952 | 2016 |
Axonal Endoplasmic Reticulum Ca2+ Content Controls Release Probability in CNS Nerve Terminals J de Juan-Sanz, GT Holt, ER Schreiter, F de Juan, DS Kim, TA Ryan Neuron 93 (4), 867-881. e6, 2017 | 238 | 2017 |
Improved methods for marking active neuron populations B Moeyaert, G Holt, R Madangopal, A Perez-Alvarez, BC Fearey, ... Nature communications 9 (1), 1-12, 2018 | 121 | 2018 |
A low affinity GCaMP3 variant (GCaMPer) for imaging the endoplasmic reticulum calcium store MJ Henderson, HA Baldwin, CA Werley, S Boccardo, LR Whitaker, X Yan, ... PLoS One 10 (10), e0139273, 2015 | 76 | 2015 |
OSPREY 3.0: Open‐source protein redesign for you, with powerful new features MA Hallen, JW Martin, A Ojewole, JD Jou, AU Lowegard, MS Frenkel, ... Journal of Computational Chemistry 39 (30), 2494-2507, 2018 | 67 | 2018 |
Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus SM Reeve, D Si, J Krucinska, Y Yan, K Viswanathan, S Wang, GT Holt, ... ACS infectious diseases 5 (11), 1896-1906, 2019 | 14 | 2019 |
Novel, provable algorithms for efficient ensemble-based computational protein design and their application to the redesign of the c-Raf-RBD: KRas protein-protein interface AU Lowegard, MS Frenkel, GT Holt, JD Jou, AA Ojewole, BR Donald PLOS Computational Biology 16 (6), e1007447, 2020 | 13 | 2020 |
Computational analysis of energy landscapes reveals dynamic features that contribute to binding of inhibitors to CFTR-associated ligand GT Holt, JD Jou, NP Gill, AU Lowegard, JW Martin, DR Madden, ... The Journal of Physical Chemistry B 123 (49), 10441-10455, 2019 | 9 | 2019 |
Minimization-Aware Recursive K*: A Novel, Provable Algorithm that Accelerates Ensemble-Based Protein Design and Provably Approximates the Energy Landscape JD Jou, GT Holt, AU Lowegard, BR Donald Journal of Computational Biology 27 (4), 550-564, 2020 | 8 | 2020 |
Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus S Wang, SM Reeve, GT Holt, AA Ojewole, MS Frenkel, P Gainza, ... PLoS computational biology 18 (2), e1009855, 2022 | 7 | 2022 |
Minimization-Aware Recursive (): A Novel, Provable Algorithm that Accelerates Ensemble-Based Protein Design and Provably Approximates the Energy … JD Jou, GT Holt, AU Lowegard, BR Donald Research in Computational Molecular Biology: 23rd Annual International …, 2019 | 3 | 2019 |
Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design GT Holt, J Gorman, S Wang, AU Lowegard, B Zhang, T Liu, BC Lin, ... Cell Reports 42 (7), 112711, 2023 | 2 | 2023 |
Toward Broad Spectrum DHFR inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus SM Reeve, D Si, J Krucinska, Y Yan, K Viswanathan, S Wang, GT Holt, ... ACS infectious diseases 5 (11), 1896, 2019 | 2 | 2019 |
Improved red protein indicators for in vivo calcium imaging H Dana, Y Sun, JP Hasseman, G Tsegaye, GT Holt, BF Fosque, ... Program#/Poster 566, 2014 | 2 | 2014 |
Ensemble-based Computational Protein Design: Novel Algorithms and Applications to Energy Landscape Approximation, Antibiotic Resistance, and Antibody Design GT Holt | | 2022 |