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Yang Yang
Yang Yang
Associate Professor, Purdue University
Verified email at purdue.edu - Homepage
Title
Cited by
Cited by
Year
The NaV1.7 sodium channel: from molecule to man
SD Dib-Hajj, Y Yang, JA Black, SG Waxman
Nature Reviews Neuroscience 14 (1), 49-62, 2013
6112013
Nav1. 8 expression is not restricted to nociceptors in mouse peripheral nervous system
SD Shields, HS Ahn, Y Yang, C Han, RP Seal, JN Wood, SG Waxman, ...
PAIN« 153 (10), 2017-2030, 2012
2732012
Small-fiber neuropathy Nav1. 8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons
J Huang, Y Yang, P Zhao, MM Gerrits, JGJ Hoeijmakers, K Bekelaar, ...
Journal of Neuroscience 33 (35), 14087-14097, 2013
1312013
Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Nav1.7 mutant channel
Y Yang, SD Dib-Hajj, J Zhang, Y Zhang, L Tyrrell, M Estacion, ...
Nature communications 3 (1), 1186, 2012
1012012
PKA phosphorylation of SUR2B subunit underscores vascular KATP channel activation by beta-adrenergic receptors
Y Shi, Z Wu, N Cui, W Shi, Y Yang, X Zhang, A Rojas, BT Ha, C Jiang
American Journal of Physiology-Regulatory, Integrative and Comparativeá…, 2007
912007
Pharmacotherapy for pain in a family with inherited erythromelalgia guided by genomic analysis and functional profiling
P Geha, Y Yang, M Estacion, BR Schulman, H Tokuno, AV Apkarian, ...
JAMA neurology 73 (6), 659-667, 2016
882016
The domain II S4-S5 linker in Nav1. 9: a missense mutation enhances activation, impairs fast inactivation, and produces human painful neuropathy
C Han, Y Yang, BTA de Greef, JGJ Hoeijmakers, MM Gerrits, ...
Neuromolecular medicine 17, 158-169, 2015
882015
Nav1. 7-A1632G mutation from a family with inherited erythromelalgia: enhanced firing of dorsal root ganglia neurons evoked by thermal stimuli
Y Yang, J Huang, MA Mis, M Estacion, L Macala, P Shah, BR Schulman, ...
Journal of Neuroscience 36 (28), 7511-7522, 2016
832016
Resilience to pain: a peripheral component identified using induced pluripotent stem cells and dynamic clamp
MA Mis, Y Yang, BS Tanaka, C Gomis-Perez, S Liu, F Dib-Hajj, T Adi, ...
Journal of Neuroscience 39 (3), 382-392, 2019
822019
Oxidative stress inhibits vascular KATP channels by S-glutathionylation
Y Yang, W Shi, N Cui, Z Wu, C Jiang
Journal of biological chemistry 285 (49), 38641-38648, 2010
802010
NaV1. 7 as a pharmacogenomic target for pain: moving toward precision medicine
Y Yang, MA Mis, M Estacion, SD Dib-Hajj, SG Waxman
Trends in pharmacological sciences 39 (3), 258-275, 2018
652018
Functional elements on SIRPα IgV domain mediate cell surface binding to CD47
Y Liu, Q Tong, Y Zhou, HW Lee, JJ Yang, HJ BŘhring, YT Chen, B Ha, ...
Journal of molecular biology 365 (3), 680-693, 2007
652007
Familial gain-of-function Nav1. 9 mutation in a painful channelopathy
C Han, Y Yang, RH Te Morsche, JPH Drenth, JM Politei, SG Waxman, ...
Journal of Neurology, Neurosurgery & Psychiatry 88 (3), 233-240, 2017
622017
Lipopolysaccharides up-regulate Kir6. 1/SUR2B channel expression and enhance vascular KATP channel activity via NF-κB-dependent signaling
W Shi, N Cui, Z Wu, Y Yang, S Zhang, H Gai, D Zhu, C Jiang
Journal of biological chemistry 285 (5), 3021-3029, 2010
592010
PKA-dependent activation of the vascular smooth muscle isoform of KATP channels by vasoactive intestinal polypeptide and its effect on relaxation of the mesenteric resistanceá…
Y Yang, Y Shi, S Guo, S Zhang, N Cui, W Shi, D Zhu, C Jiang
Biochimica et Biophysica Acta (BBA)-Biomembranes 1778 (1), 88-96, 2008
532008
Multistate structural modeling and voltage-clamp analysis of epilepsy/autism mutation Kv10. 2–R327H demonstrate the role of this residue in stabilizing the channel closed state
Y Yang, DV Vasylyev, F Dib-Hajj, KR Veeramah, MF Hammer, ...
Journal of Neuroscience 33 (42), 16586-16593, 2013
512013
Molecular basis and structural insight of vascular KATP channel gating by S-glutathionylation
Y Yang, W Shi, X Chen, N Cui, AS Konduru, Y Shi, TC Trower, S Zhang, ...
Journal of biological chemistry 286 (11), 9298-9307, 2011
482011
Severe deficiency of the voltage-gated sodium channel NaV1. 2 elevates neuronal excitability in adult mice
J Zhang, X Chen, M Eaton, J Wu, Z Ma, S Lai, A Park, TS Ahmad, Z Que, ...
Cell reports 36 (5), 2021
462021
KATP channel action in vascular tone regulation: from genetics to diseases
SHI Wei-Wei, Y Yang, SHI Yun, J Chun
Sheng li xue bao:[Acta physiologica Sinica] 64 (1), 1, 2012
452012
cAMP-dependent protein kinase phosphorylation produces interdomain movement in SUR2B leading to activation of the vascular KATP channel
Y Shi, X Chen, Z Wu, W Shi, Y Yang, N Cui, C Jiang, RW Harrison
Journal of Biological Chemistry 283 (12), 7523-7530, 2008
442008
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