| Role of a buried acid group in the mechanism of action of chymotrypsin DM Blow, JJ Birktoft, BS Hartley Nature 221 (5178), 337-340, 1969 | 1458 | 1969 |
| From molecular to macroscopic via the rational design of a self-assembled 3D DNA crystal J Zheng, JJ Birktoft, Y Chen, T Wang, R Sha, PE Constantinou, SL Ginell, ... Nature 461 (7260), 74-77, 2009 | 993 | 2009 |
| Structure of crystalline α-chymotrypsin: V. The atomic structure of tosyl-α-chymotrypsin at 2 Å resolution JJ Birktoft, DM Blow Journal of molecular biology 68 (2), 187-240, 1972 | 846 | 1972 |
| Subtilisin. Stereochemical mechanism involving transition-state stabilization JD Robertus, J Kraut, RA Alden, JJ Birktoft Biochemistry 11 (23), 4293-4303, 1972 | 498 | 1972 |
| Structure and biology of tissue factor pathway inhibitor MS Bajaj, JJ Birktoft, SA Steer, SP Bajaj Thrombosis and haemostasis 86 (10), 959-972, 2001 | 368 | 2001 |
| X-ray crystallographic study of boronic acid adducts with subtilisin BPN'(Novo). A model for the catalytic transition state. DA Matthews, RA Alden, JJ Birktoft, ST Freer, J Kraut Journal of Biological Chemistry 250 (18), 7120-7126, 1975 | 270 | 1975 |
| Structures of HIV-1 reverse transcriptase with pre-and post-translocation AZTMP-terminated DNA SG Sarafianos, AD Clark, K Das, S Tuske, JJ Birktoft, P Ilankumaran, ... The EMBO journal 21 (23), 6614-6624, 2002 | 255 | 2002 |
| Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation S Tuske, SG Sarafianos, X Wang, B Hudson, E Sineva, J Mukhopadhyay, ... Cell 122 (4), 541-552, 2005 | 231 | 2005 |
| X-ray crystallographic study of the binding of peptide chloromethyl ketone inhibitors to subtilisin BPN JD Robertus, RA Alden, JJ Birktoft, J Kraut, JC Powers, PE Wilcox Biochemistry 11 (13), 2439-2449, 1972 | 225 | 1972 |
| The presence of a histidine-aspartic acid pair in the active site of 2-hydroxyacid dehydrogenases. X-ray refinement of cytoplasmic malate dehydrogenase. JJ Birktoft, LJ Banaszak Journal of Biological Chemistry 258 (1), 472-482, 1983 | 198 | 1983 |
| Determinants of protein thermostability observed in the 1.9-. ANG. crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus CA Kelly, M Nishiyama, Y Ohnishi, T Beppu, JJ Birktoft Biochemistry 32 (15), 3913-3922, 1993 | 177 | 1993 |
| Refined crystal structure of cytoplasmic malate dehydrogenase at 2.5-. ANG. resolution JJ Birktoft, G Rhodes, LJ Banaszak Biochemistry 28 (14), 6065-6081, 1989 | 172 | 1989 |
| Amino acid sequence homology among the 2-hydroxy acid dehydrogenases: mitochondrial and cytoplasmic malate dehydrogenases form a homologous system with lactate dehydrogenase. JJ Birktoft, RT Fernley, RA Bradshaw, LJ Banaszak Proceedings of the National Academy of Sciences 79 (20), 6166-6170, 1982 | 164 | 1982 |
| Single amino acid substitutions dissociate fibrinogen-clotting and thrombomodulin-binding activities of human thrombin. QY Wu, JP Sheehan, M Tsiang, SR Lentz, JJ Birktoft, JE Sadler Proceedings of the National Academy of Sciences 88 (15), 6775-6779, 1991 | 160 | 1991 |
| Polypeptide halomethyl ketones bind to serine proteases as analogs of the tetrahedral intermediate. X-ray crystallographic comparison of lysine-and phenylalanine-polypeptide … TL Poulos, RA Alden, ST Freer, JJ Birktoft, J Kraut Journal of Biological Chemistry 251 (4), 1097-1103, 1976 | 152 | 1976 |
| Atomic coordinates for subtilisin BPN′(or Novo) RA Alden, JJ Birktoft, J Kraut, JD Robertus, CS Wright Biochemical and Biophysical Research Communications 45 (2), 337-344, 1971 | 147 | 1971 |
| Re-examination of the charge relay system in subtilisin comparison with other serine proteases. DA Matthews, RA Alden, JJ Birktoft, T Freer, J Kraut The Journal of biological chemistry 252 (24), 8875-8883, 1977 | 142 | 1977 |
| Crystal structure of a continuous three-dimensional DNA lattice PJ Paukstelis, J Nowakowski, JJ Birktoft, NC Seeman Chemistry & biology 11 (8), 1119-1126, 2004 | 130 | 2004 |
| Atomic CO-ordinates for tosyl-α-chymotrypsin JJ Birktoft, BW Matthews, DM Blow Biochemical and biophysical research communications 36 (1), 131-137, 1969 | 125 | 1969 |
| I. Serine proteinases. The structure of α-chymotrypsin JJ Birktoft, DM Blow, R Henderson, TA Steizt Philosophical Transactions of the Royal Society of London. B, Biological …, 1970 | 119 | 1970 |
