Maria Pia Rigobello
Maria Pia Rigobello
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Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs
A Bindoli, MP Rigobello, G Scutari, C Gabbiani, A Casini, L Messori
Coordination Chemistry Reviews 253 (11-12), 1692-1707, 2009
Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells
C Marzano, V Gandin, A Folda, G Scutari, A Bindoli, MP Rigobello
Free Radical Biology and Medicine 42 (6), 872-881, 2007
Biochemical and toxicological properties of the oxidation products of catecholamines
A Bindoli, MP Rigobello, DJ Deeble
Free Radical Biology and Medicine 13 (4), 391-405, 1992
Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium (II)− arene compounds
A Casini, C Gabbiani, F Sorrentino, MP Rigobello, A Bindoli, TJ Geldbach, ...
Journal of medicinal chemistry 51 (21), 6773-6781, 2008
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach, T Kietzmann, ...
Redox biology 13, 94-162, 2017
Cancer cell death induced by phosphine gold (I) compounds targeting thioredoxin reductase
V Gandin, AP Fernandes, MP Rigobello, B Dani, F Sorrentino, F Tisato, ...
Biochemical pharmacology 79 (2), 90-101, 2010
Gold(I) Carbene Complexes Causing Thioredoxin 1 and Thioredoxin 2 Oxidation as Potential Anticancer Agents
E Schuh, C Pflüger, A Citta, A Folda, MP Rigobello, A Bindoli, A Casini, ...
Journal of medicinal chemistry 55 (11), 5518-5528, 2012
Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions
MP Rigobello, L Messori, G Marcon, MA Cinellu, M Bragadin, A Folda, ...
Journal of inorganic biochemistry 98 (10), 1634-1641, 2004
Induction of mitochondrial permeability transition by auranofin, a gold (I)-phosphine derivative
MP Rigobello, G Scutari, R Boscolo, A Bindoli
British journal of pharmacology 136 (8), 1162, 2002
Principles in redox signaling: from chemistry to functional significance
A Bindoli, MP Rigobello
Antioxidants & redox signaling 18 (13), 1557-1593, 2013
Mitochondrial thioredoxin reductase inhibition by gold (I) compounds and concurrent stimulation of permeability transition and release of cytochrome c
MP Rigobello, G Scutari, A Folda, A Bindoli
Biochemical pharmacology 67 (4), 689-696, 2004
Purification of mitochondrial thioredoxin reductase and its involvement in the redox regulation of membrane permeability
MP Rigobello, MT Callegaro, E Barzon, M Benetti, A Bindoli
Free Radical Biology and Medicine 24 (2), 370-376, 1998
Gold (III)-dithiocarbamato complexes induce cancer cell death triggered by thioredoxin redox system inhibition and activation of ERK pathway
D Saggioro, MP Rigobello, L Paloschi, A Folda, SA Moggach, S Parsons, ...
Chemistry & biology 14 (10), 1128-1139, 2007
Fluorescent silver(i) and gold(i)–N-heterocyclic carbene complexes with cytotoxic properties: mechanistic insights
A Citta, E Schuh, F Mohr, A Folda, ML Massimino, A Bindoli, A Casini, ...
Metallomics 5 (8), 1006-1015, 2013
In vitro antitumour activity of water soluble Cu (I), Ag (I) and Au (I) complexes supported by hydrophilic alkyl phosphine ligands
C Santini, M Pellei, G Papini, B Morresi, R Galassi, S Ricci, F Tisato, ...
Journal of Inorganic Biochemistry 105 (2), 232-240, 2011
Milk-derived bioactive peptides exhibit antioxidant activity through the Keap1-Nrf2 signaling pathway
F Tonolo, A Folda, L Cesaro, V Scalcon, O Marin, S Ferro, A Bindoli, ...
Journal of Functional Foods 64, 103696, 2020
Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold (I) complexes …
E Vergara, A Casini, F Sorrentino, O Zava, E Cerrada, MP Rigobello, ...
ChemMedChem: Chemistry Enabling Drug Discovery 5 (1), 96-102, 2010
The mitochondrial antioxidant defence system and its response to oxidative stress
T Rabilloud, M Heller, MP Rigobello, A Bindoli, R Aebersold, J Lunardi
PROTEOMICS: International Edition 1 (9), 1105-1110, 2001
Effect of auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase
MP Rigobello, A Folda, MC Baldoin, G Scutari, A Bindoli
Free radical research 39 (7), 687-695, 2005
Toxicity of aminochromes
A Bindoli, MP Rigobello, L Galzigna
Toxicology letters 48 (1), 3-20, 1989
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