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George A Cortina
George A Cortina
Verified email at duke.edu
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Year
Predicting allosteric mutants that increase activity of a major antibiotic resistance enzyme
MJ Latallo, GA Cortina, S Faham, RK Nakamoto, PM Kasson
Chemical science 8 (9), 6484-6492, 2017
322017
Conformational intermediate that controls KPC-2 catalysis and beta-lactam drug resistance
GA Cortina, JM Hays, PM Kasson
ACS catalysis 8 (4), 2741-2747, 2018
252018
Excess positional mutual information predicts both local and allosteric mutations affecting beta lactamase drug resistance
GA Cortina, PM Kasson
Bioinformatics 32 (22), 3420-3427, 2016
242016
Population genetics of introduced bullfrogs, Rana (Lithobates) catesbeianus, in the Willamette Valley, Oregon, USA
WC Funk, TS Garcia, GA Cortina, RH Hill
Biological Invasions 13, 651-658, 2011
222011
Bifunctional substrate activation via an arginine residue drives catalysis in chalcone isomerases
JR Burke, JJ La Clair, RN Philippe, A Pabis, M Corbella, JM Jez, ...
ACS Catalysis 9 (9), 8388-8396, 2019
132019
Predicting allostery and microbial drug resistance with molecular simulations
GA Cortina, PM Kasson
Current opinion in structural biology 52, 80-86, 2018
132018
Identifying a Conformational Transition Critical for Carbapenem Drug Resistance
GA Cortina, P Kasson
Biophysical Journal 114 (3), 48a, 2018
2018
Identifying Determinants of Antibiotic Resistance in Beta-lactamases
GA Cortina
University of Virginia, 2018
2018
Predicting Residues that Increase Antibiotic Resistance of CTX-M9 Enzymes using Molecular Simulation and Statistical Learning
GA Cortina, MJ Latallo, PM Kasson
Biophysical Journal 112 (3), 317a, 2017
2017
Understanding allosteric modulation of beta lactamase function and bacterial drug resistance
P Kasson, G Cortina, M Latallo
Abstracts of Papers of the American Chemical Society 254, 2017
2017
Novel Allosteric Mutations Increasing Cephalosporin Resistance of CTX-M9 Beta Lactamases
MJ Latallo, GA Cortina, PM Kasson
Biophysical Journal 110 (3), 384a, 2016
2016
Electronic Supplementary Information for Predicting allosteric mutants that increase activity of a major antibiotic resistance enzyme
MJ Latallo, GA Cortina, RK Nakamoto, S Faham, PM Kasson
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Articles 1–12