Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer W Chung, HH Eum, HO Lee, KM Lee, HB Lee, KT Kim, HS Ryu, S Kim, ... Nature communications 8 (1), 1-12, 2017 | 738 | 2017 |
The somatic genomic landscape of chromophobe renal cell carcinoma CF Davis, CJ Ricketts, M Wang, L Yang, AD Cherniack, H Shen, C Buhay, ... Cancer cell 26 (3), 319-330, 2014 | 717 | 2014 |
Clonal evolution of glioblastoma under therapy J Wang, E Cazzato, E Ladewig, V Frattini, DIS Rosenbloom, S Zairis, ... Nature genetics 48 (7), 768-776, 2016 | 590 | 2016 |
A molecular portrait of microsatellite instability across multiple cancers I Cortes-Ciriano, S Lee, WY Park, TM Kim, PJ Park Nature communications 8 (1), 15180, 2017 | 453 | 2017 |
Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas KM Joo, SY Kim, X Jin, SY Song, DS Kong, JII Lee, JW Jeon, MH Kim, ... Laboratory investigation 88 (8), 808-815, 2008 | 392 | 2008 |
Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma N Kim, HK Kim, K Lee, Y Hong, JH Cho, JW Choi, JI Lee, YL Suh, BM Ku, ... Nature communications 11 (1), 2285, 2020 | 383 | 2020 |
A highly annotated whole-genome sequence of a Korean individual JI Kim, YS Ju, H Park, S Kim, S Lee, JH Yi, J Mudge, NA Miller, D Hong, ... nature 460 (7258), 1011-1015, 2009 | 382 | 2009 |
Intron retention is a widespread mechanism of tumor-suppressor inactivation H Jung, D Lee, J Lee, D Park, YJ Kim, WY Park, D Hong, PJ Park, E Lee Nature genetics 47 (11), 1242-1248, 2015 | 310 | 2015 |
Spatiotemporal evolution of the primary glioblastoma genome J Kim, IH Lee, HJ Cho, CK Park, YS Jung, Y Kim, SH Nam, BS Kim, ... Cancer cell 28 (3), 318-328, 2015 | 275 | 2015 |
Up-regulation of caveolin attenuates epidermal growth factor signaling in senescent cells WY Park, JS Park, KA Cho, DI Kim, YG Ko, JS Seo, SC Park Journal of Biological Chemistry 275 (27), 20847-20852, 2000 | 264 | 2000 |
A single recurrent mutation in the 5′-UTR of IFITM5 causes osteogenesis imperfecta type V TJ Cho, KE Lee, SK Lee, SJ Song, KJ Kim, D Jeon, G Lee, HN Kim, ... The American Journal of Human Genetics 91 (2), 343-348, 2012 | 260 | 2012 |
Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells KT Kim, HW Lee, HO Lee, SC Kim, YJ Seo, W Chung, HH Eum, DH Nam, ... Genome biology 16, 1-15, 2015 | 254 | 2015 |
Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer HO Lee, Y Hong, HE Etlioglu, YB Cho, V Pomella, B Van den Bosch, ... Nature genetics 52 (6), 594-603, 2020 | 237 | 2020 |
Spatiotemporal genomic architecture informs precision oncology in glioblastoma JK Lee, J Wang, JK Sa, E Ladewig, HO Lee, IH Lee, HJ Kang, ... Nature genetics 49 (4), 594-599, 2017 | 225 | 2017 |
Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability G Ince-Dunn, HJ Okano, KB Jensen, WY Park, R Zhong, J Ule, A Mele, ... Neuron 75 (6), 1067-1080, 2012 | 190 | 2012 |
Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma KT Kim, HW Lee, HO Lee, HJ Song, DE Jeong, S Shin, H Kim, Y Shin, ... Genome biology 17 (1), 1-17, 2016 | 185 | 2016 |
IL-6 protects pancreatic islet beta cells from pro-inflammatory cytokines-induced cell death and functional impairment in vitro and in vivo SE Choi, KM Choi, IH Yoon, JY Shin, JS Kim, WY Park, DJ Han, SC Kim, ... Transplant immunology 13 (1), 43-53, 2004 | 177 | 2004 |
Frizzled 4 Regulates Stemness and Invasiveness of Migrating Glioma Cells Established by Serial Intracranial TransplantationFrizzled 4 and Glioma Invasiveness X Jin, HY Jeon, KM Joo, JK Kim, J Jin, SH Kim, BG Kang, S Beck, SJ Lee, ... Cancer research 71 (8), 3066-3075, 2011 | 165 | 2011 |
Linking transcriptional and genetic tumor heterogeneity through allele analysis of single-cell RNA-seq data J Fan, HO Lee, S Lee, D Ryu, S Lee, C Xue, SJ Kim, K Kim, N Barkas, ... Genome research 28 (8), 1217-1227, 2018 | 159 | 2018 |
Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling HM Jeon, X Jin, JS Lee, SY Oh, YW Sohn, HJ Park, KM Joo, WY Park, ... Genes & development 22 (15), 2028-2033, 2008 | 156 | 2008 |