Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs M Fribourg, JL Moreno, T Holloway, D Provasi, L Baki, R Mahajan, G Park, ... Cell 147 (5), 1011-1023, 2011 | 333 | 2011 |
Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activation DA Braun, M Fribourg, SC Sealfon Journal of Biological Chemistry 288 (5), 2986-2993, 2013 | 209 | 2013 |
Signaling through the inhibitory Fc receptor FcγRIIB induces CD8+ T cell apoptosis to limit T cell immunity AB Morris, CR Farley, DF Pinelli, LE Adams, MS Cragg, JM Boss, ... Immunity 52 (1), 136-150. e6, 2020 | 103 | 2020 |
Innate immune response to influenza virus at single-cell resolution in human epithelial cells revealed paracrine induction of interferon lambda 1 I Ramos, G Smith, F Ruf-Zamojski, C Martínez-Romero, M Fribourg, ... Journal of virology 93 (20), 10.1128/jvi. 00559-19, 2019 | 96 | 2019 |
Single-cell analysis shows that paracrine signaling by first responder cells shapes the interferon-β response to viral infection S Patil, M Fribourg, Y Ge, M Batish, S Tyagi, F Hayot, SC Sealfon Science signaling 8 (363), ra16-ra16, 2015 | 83 | 2015 |
T-cell exhaustion correlates with improved outcomes in kidney transplant recipients M Fribourg, L Anderson, C Fischman, C Cantarelli, L Perin, G La Manna, ... Kidney international 96 (2), 436-449, 2019 | 71 | 2019 |
Interactive big data resource to elucidate human immune pathways and diseases D Gorenshteyn, E Zaslavsky, M Fribourg, CY Park, AK Wong, A Tadych, ... Immunity 43 (3), 605-614, 2015 | 67 | 2015 |
Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis A Angeletti, C Cantarelli, A Petrosyan, S Andrighetto, K Budge, ... Journal of Experimental Medicine 217 (9), e20191699, 2020 | 63 | 2020 |
Mechanism of PLC-mediated Kir3 current inhibition I Keselman, M Fribourg, DP Felsenfeld, DE Logothetis Channels 1 (2), 113-123, 2007 | 63 | 2007 |
Erythropoietin receptor-mediated molecular crosstalk promotes T cell immunoregulation and transplant survival C Purroy, RL Fairchild, T Tanaka, WM Baldwin III, J Manrique, JC Madsen, ... Journal of the American Society of Nephrology 28 (8), 2377-2392, 2017 | 60 | 2017 |
The spatially resolved transcriptional profile of acute T cell–mediated rejection in a kidney allograft F Salem, L Perin, S Sedrakyan, A Angeletti, GM Ghiggeri, MC Coccia, ... Kidney international 101 (1), 131-136, 2022 | 46 | 2022 |
Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells L Baki, M Fribourg, J Younkin, JM Eltit, JL Moreno, G Park, Z Vysotskaya, ... Pflügers Archiv-European Journal of Physiology 468, 775-793, 2016 | 39 | 2016 |
Human dendritic cell response signatures distinguish 1918, pandemic, and seasonal H1N1 influenza viruses BM Hartmann, J Thakar, RA Albrecht, S Avey, E Zaslavsky, N Marjanovic, ... Journal of virology 89 (20), 10190-10205, 2015 | 39 | 2015 |
Interclass GPCR heteromerization affects localization and trafficking R Toneatti, JM Shin, UH Shah, CR Mayer, JM Saunders, M Fribourg, ... Science signaling 13 (654), eaaw3122, 2020 | 33 | 2020 |
CyTOF-enabled analysis identifies class-switched B cells as the main lymphocyte subset associated with disease relapse in children with idiopathic nephrotic syndrome M Fribourg, M Cioni, GM Ghiggeri, C Cantarelli, JS Leventhal, K Budge, ... Frontiers in Immunology 12, 726428, 2021 | 32 | 2021 |
C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans DA Verghese, N Chun, K Paz, M Fribourg, TM Woodruff, R Flynn, Y Hu, ... JCI insight 3 (24), 2018 | 32 | 2018 |
C5aR1 regulates migration of suppressive myeloid cells required for costimulatory blockade-induced murine allograft survival I Llaudo, M Fribourg, ME Medof, P Conde, J Ochando, PS Heeger American Journal of Transplantation 19 (3), 633-645, 2019 | 30 | 2019 |
G protein-coupled receptor signaling to Kir channels in Xenopus oocytes C Hatcher-Solis, M Fribourg, K Spyridaki, J Younkin, A Ellaithy, G Xiang, ... Current pharmaceutical biotechnology 15 (10), 987-995, 2014 | 30 | 2014 |
Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation F Fueyo-González, M McGinty, M Ningoo, L Anderson, C Cantarelli, ... Immunity 55 (3), 459-474. e7, 2022 | 28 | 2022 |
T cell expression of C5a receptor 2 augments murine regulatory T cell (TREG) generation and TREG-dependent cardiac allograft survival D A Verghese, M Demir, N Chun, M Fribourg, P Cravedi, I Llaudo, ... The Journal of Immunology 200 (6), 2186-2198, 2018 | 26 | 2018 |