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Ryan M. Young
Ryan M. Young
NCI
Verified email at mail.nih.gov - Homepage
Title
Cited by
Cited by
Year
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
RE Davis, VN Ngo, G Lenz, P Tolar, RM Young, PB Romesser, ...
Nature 463 (7277), 88-92, 2010
16762010
Oncogenically active MYD88 mutations in human lymphoma
VN Ngo, RM Young, R Schmitz, S Jhavar, W Xiao, KH Lim, ...
Nature 470 (7332), 115-119, 2011
15432011
Genetics and pathogenesis of diffuse large B-cell lymphoma
R Schmitz, GW Wright, DW Huang, CA Johnson, JD Phelan, JQ Wang, ...
New England Journal of Medicine 378 (15), 1396-1407, 2018
12702018
Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma
WH Wilson, RM Young, R Schmitz, Y Yang, S Pittaluga, G Wright, CJ Lih, ...
Nature medicine 21 (8), 922-926, 2015
10082015
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
R Schmitz, RM Young, M Ceribelli, S Jhavar, W Xiao, M Zhang, G Wright, ...
Nature 490 (7418), 116-120, 2012
8632012
Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma
Y Yang, AL Shaffer, NCT Emre, M Ceribelli, M Zhang, G Wright, W Xiao, ...
Cancer cell 21 (6), 723-737, 2012
5402012
Pathogenesis of human B cell lymphomas
AL Shaffer III, RM Young, LM Staudt
Annual review of immunology 30, 565-610, 2012
4772012
Targeting pathological B cell receptor signalling in lymphoid malignancies
RM Young, LM Staudt
Nature reviews Drug discovery 12 (3), 229-243, 2013
4272013
A probabilistic classification tool for genetic subtypes of diffuse large B cell lymphoma with therapeutic implications
GW Wright, JD Phelan, ZA Coulibaly, S Roulland, RM Young, JQ Wang, ...
Cancer cell 37 (4), 551-568. e14, 2020
4092020
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells
LA Mathews Griner, R Guha, P Shinn, RM Young, JM Keller, D Liu, ...
Proceedings of the National Academy of Sciences 111 (6), 2349-2354, 2014
3702014
A multiprotein supercomplex controlling oncogenic signalling in lymphoma
JD Phelan, RM Young, DE Webster, S Roulland, GW Wright, M Kasbekar, ...
Nature 560 (7718), 387-391, 2018
2632018
B-cell receptor signaling in diffuse large B-cell lymphoma
RM Young, AL Shaffer III, JD Phelan, LM Staudt
Seminars in hematology 52 (2), 77-85, 2015
1982015
A lipid raft environment enhances Lyn kinase activity by protecting the active site tyrosine from dephosphorylation
RM Young, D Holowka, B Baird
Journal of Biological Chemistry 278 (23), 20746-20752, 2003
1982003
Lipid segregation and IgE receptor signaling: a decade of progress
D Holowka, JA Gosse, AT Hammond, X Han, P Sengupta, NL Smith, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1746 (3), 252-259, 2005
1762005
Function and regulation of SPLUNC1 protein in Mycoplasma infection and allergic inflammation
HW Chu, J Thaikoottathil, JG Rino, G Zhang, Q Wu, T Moss, Y Refaeli, ...
The Journal of Immunology 179 (6), 3995-4002, 2007
1642007
Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens
RM Young, T Wu, R Schmitz, M Dawood, W Xiao, JD Phelan, W Xu, ...
Proceedings of the National Academy of Sciences 112 (44), 13447-13454, 2015
1502015
Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target
RM Young, IR Hardy, RL Clarke, N Lundy, P Pine, BC Turner, TA Potter, ...
Blood, The Journal of the American Society of Hematology 113 (11), 2508-2516, 2009
1362009
The B Cell Antigen Receptor and Overexpression of MYC Can Cooperate in the Genesis of B Cell Lymphomas
Y Refaeli, RM Young, BC Turner, J Duda, KA Field, JM Bishop
PLoS biology 6 (6), e152, 2008
1292008
Targeting non-proteolytic protein ubiquitination for the treatment of diffuse large B cell lymphoma
Y Yang, P Kelly, AL Shaffer, R Schmitz, HM Yoo, X Liu, D Webster, ...
Cancer cell 29 (4), 494-507, 2016
862016
Pathogenic B‐cell receptor signaling in lymphoid malignancies: new insights to improve treatment
RM Young, JD Phelan, WH Wilson, LM Staudt
Immunological reviews 291 (1), 190-213, 2019
752019
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