NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells SW Paugh, EJ Bonten, D Savic, LB Ramsey, WE Thierfelder, P Gurung, ... Nature genetics 47 (6), 607-614, 2015 | 157 | 2015 |
Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia C Liu, JD Kawedia, C Cheng, D Pei, CA Fernandez, X Cai, KR Crews, ... Leukemia 26 (11), 2303-2309, 2012 | 128 | 2012 |
Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia SE Karol, W Yang, SL Van Driest, TY Chang, S Kaste, E Bowton, ... Blood, The Journal of the American Society of Hematology 126 (15), 1770-1776, 2015 | 113 | 2015 |
HLA-DRB1*07:01 is associated with a higher risk of asparaginase allergies CA Fernandez, C Smith, W Yang, M Daté, D Bashford, E Larsen, ... Blood, The Journal of the American Society of Hematology 124 (8), 1266-1276, 2014 | 113 | 2014 |
A clinician‐driven automated system for integration of pharmacogenetic interpretations into an electronic medical record JK Hicks, KR Crews, JM Hoffman, NM Kornegay, MR Wilkinson, R Lorier, ... Clinical Pharmacology & Therapeutics 92 (5), 563-566, 2012 | 113 | 2012 |
Doxorubicin delivered by a redox-responsive dasatinib-containing polymeric prodrug carrier for combination therapy J Sun, Y Liu, Y Chen, W Zhao, Q Zhai, S Rathod, Y Huang, S Tang, ... Journal of Controlled Release 258, 43-55, 2017 | 105 | 2017 |
Dexamethasone exposure and asparaginase antibodies affect relapse risk in acute lymphoblastic leukemia JD Kawedia, C Liu, D Pei, C Cheng, CA Fernandez, SC Howard, ... Blood, The Journal of the American Society of Hematology 119 (7), 1658-1664, 2012 | 102 | 2012 |
Engineered nanoscaled polyplex gene delivery systems CA Fernandez, KG Rice Molecular pharmaceutics 6 (5), 1277-1289, 2009 | 78 | 2009 |
Genome-wide analysis links NFATC2 with asparaginase hypersensitivity CA Fernandez, C Smith, W Yang, CG Mullighan, C Qu, E Larsen, ... Blood, The Journal of the American Society of Hematology 126 (1), 69-75, 2015 | 77 | 2015 |
Genetic risk factors for the development of osteonecrosis in children under age 10 treated for acute lymphoblastic leukemia SE Karol, LA Mattano Jr, W Yang, KW Maloney, C Smith, CC Liu, ... Blood, The Journal of the American Society of Hematology 127 (5), 558-564, 2016 | 65 | 2016 |
Synthesis and in vitro testing of new potent polyacridine− melittin gene delivery peptides NJ Baumhover, K Anderson, CA Fernandez, KG Rice Bioconjugate chemistry 21 (1), 74-83, 2010 | 54 | 2010 |
Genome‐Wide Study Links PNPLA3 Variant With Elevated Hepatic Transaminase After Acute Lymphoblastic Leukemia Therapy Y Liu, CA Fernandez, C Smith, W Yang, C Cheng, JC Panetta, ... Clinical Pharmacology & Therapeutics 102 (1), 131-140, 2017 | 51 | 2017 |
Metabolically stabilized long-circulating PEGylated polyacridine peptide polyplexes mediate hydrodynamically stimulated gene expression in liver CA Fernandez, NJ Baumhover, JT Duskey, S Khargharia, K Kizzire, ... Gene therapy 18 (1), 23-37, 2011 | 50 | 2011 |
Excess of proximal microsatellite-stable colorectal cancer in African Americans from a multiethnic study RM Xicola, M Gagnon, JR Clark, T Carroll, W Gao, C Fernandez, D Mijic, ... Clinical Cancer Research 20 (18), 4962-4970, 2014 | 46 | 2014 |
Concordance of DMET plus genotyping results with those of orthogonal genotyping methods CA Fernandez, C Smith, W Yang, R Lorier, KR Crews, N Kornegay, ... Clinical Pharmacology & Therapeutics 92 (3), 360-365, 2012 | 46 | 2012 |
High-throughput asparaginase activity assay in serum of children with leukemia CA Fernandez, X Cai, A Elozory, C Liu, JC Panetta, S Jeha, AR Molinelli, ... International journal of clinical and experimental medicine 6 (7), 478, 2013 | 42 | 2013 |
Creatine based polymer for codelivery of bioengineered MicroRNA and chemodrugs against breast cancer lung metastasis J Xu, J Sun, PY Ho, Z Luo, W Ma, W Zhao, SB Rathod, CA Fernandez, ... Biomaterials 210, 25-40, 2019 | 40 | 2019 |
LincRNA-immunity landscape analysis identifies EPIC1 as a regulator of tumor immune evasion and immunotherapy resistance W Guo, Y Wang, M Yang, Z Wang, Y Wang, S Chaurasia, Z Wu, M Zhang, ... Science Advances 7 (7), eabb3555, 2021 | 32 | 2021 |
Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia SE Karol, E Larsen, C Cheng, X Cao, W Yang, LB Ramsey, ... Leukemia 31 (6), 1325-1332, 2017 | 31 | 2017 |
Successful challenges using native E. coli asparaginase after hypersensitivity reactions to PEGylated E. coli asparaginase CA Fernandez, E Stewart, JC Panetta, MR Wilkinson, AR Morrison, ... Cancer chemotherapy and pharmacology 73, 1307-1313, 2014 | 31 | 2014 |