An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control H Clevers, KM Loh, R Nusse science 346 (6205), 1248012, 2014 | 1480 | 2014 |
A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ... Cell stem cell 5 (5), 491-503, 2009 | 985 | 2009 |
Mapping the pairwise choices leading from pluripotency to human bone, heart, and other mesoderm cell types KM Loh, A Chen, PW Koh, TZ Deng, R Sinha, JM Tsai, AA Barkal, ... Cell 166 (2), 451-467, 2016 | 474 | 2016 |
Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations KM Loh, LT Ang, J Zhang, V Kumar, J Ang, JQ Auyeong, KL Lee, ... Cell stem cell 14 (2), 237-252, 2014 | 436 | 2014 |
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation AC Wilkinson, R Ishida, M Kikuchi, K Sudo, M Morita, RV Crisostomo, ... Nature 571 (7763), 117-121, 2019 | 410 | 2019 |
Generating cellular diversity and spatial form: Wnt signaling and the evolution of multicellular animals KM Loh, R van Amerongen, R Nusse Developmental cell 38 (6), 643-655, 2016 | 349 | 2016 |
Thirst-associated preoptic neurons encode an aversive motivational drive WE Allen, LA DeNardo, MZ Chen, CD Liu, KM Loh, LE Fenno, ... Science 357 (6356), 1149-1155, 2017 | 338 | 2017 |
A precarious balance: pluripotency factors as lineage specifiers KM Loh, B Lim Cell stem cell 8 (4), 363-369, 2011 | 303 | 2011 |
A roadmap for human liver differentiation from pluripotent stem cells LT Ang, AKY Tan, MI Autio, SH Goh, SH Choo, KL Lee, J Tan, B Pan, ... Cell reports 22 (8), 2190-2205, 2018 | 195 | 2018 |
Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells CKF Chan, P Lindau, W Jiang, JY Chen, LF Zhang, CC Chen, J Seita, ... Proceedings of the National Academy of Sciences 110 (31), 12643-12648, 2013 | 152 | 2013 |
Inhibition of apoptosis overcomes stage-related compatibility barriers to chimera formation in mouse embryos H Masaki, M Kato-Itoh, Y Takahashi, A Umino, H Sato, K Ito, A Yanagida, ... Cell Stem Cell 19 (5), 587-592, 2016 | 128 | 2016 |
Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards RM Martin, JL Fowler, MK Cromer, BJ Lesch, E Ponce, N Uchida, ... Nature communications 11 (1), 2713, 2020 | 93 | 2020 |
Differentiation of trophoblast cells from human embryonic stem cells: to be or not to be? RM Roberts, KM Loh, M Amita, AS Bernardo, K Adachi, AP Alexenko, ... Reproduction 147 (5), D1-D12, 2014 | 88 | 2014 |
Isolation and 3D expansion of multipotent Sox9+ mouse lung progenitors M Nichane, A Javed, V Sivakamasundari, M Ganesan, LT Ang, P Kraus, ... Nature methods 14 (12), 1205-1212, 2017 | 87 | 2017 |
Antibody conditioning enables MHC-mismatched hematopoietic stem cell transplants and organ graft tolerance BM George, KS Kao, HS Kwon, BJ Velasco, J Poyser, A Chen, AC Le, ... Cell Stem Cell 25 (2), 185-192. e3, 2019 | 77 | 2019 |
A critical look: Challenges in differentiating human pluripotent stem cells into desired cell types and organoids JL Fowler, LT Ang, KM Loh Wiley Interdisciplinary Reviews: Developmental Biology 9 (3), e368, 2020 | 74 | 2020 |
An atlas of transcriptional, chromatin accessibility, and surface marker changes in human mesoderm development PW Koh, R Sinha, AA Barkal, RM Morganti, A Chen, IL Weissman, LT Ang, ... Scientific data 3 (1), 1-15, 2016 | 59 | 2016 |
Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions J Durruthy-Durruthy, SF Briggs, J Awe, CY Ramathal, S Karumbayaram, ... PloS one 9 (4), e94231, 2014 | 58 | 2014 |
Ex uno plures: molecular designs for embryonic pluripotency KM Loh, B Lim, LT Ang Physiological reviews 95 (1), 245-295, 2015 | 47 | 2015 |
Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses LT Ang, AT Nguyen, KJ Liu, A Chen, X Xiong, M Curtis, RM Martin, ... Cell 185 (14), 2523-2541. e30, 2022 | 40 | 2022 |