Nrf2–ARE pathway: an emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases I Buendia, P Michalska, E Navarro, I Gameiro, J Egea, R Leon Pharmacology & therapeutics 157, 84-104, 2016 | 570 | 2016 |
Sequential activation of microglia and astrocyte cytokine expression precedes increased iba‐1 or GFAP immunoreactivity following systemic immune challenge DM Norden, PJ Trojanowski, E Villanueva, E Navarro, JP Godbout Glia 64 (2), 300-316, 2016 | 544 | 2016 |
Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection J Egea, I Buendia, E Parada, E Navarro, R León, MG Lopez Biochemical pharmacology 97 (4), 463-472, 2015 | 295 | 2015 |
Na+ controls hypoxic signalling by the mitochondrial respiratory chain P Hernansanz-Agustín, C Choya-Foces, S Carregal-Romero, E Ramos, ... Nature 586 (7828), 287-291, 2020 | 165 | 2020 |
Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies KP Lopes, GJL Snijders, J Humphrey, A Allan, MAM Sneeboer, E Navarro, ... Nature Genetics, 1-14, 2022 | 124 | 2022 |
Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia P Hernansanz-Agustín, E Ramos, E Navarro, E Parada, ... Redox biology 12, 1040-1051, 2017 | 113 | 2017 |
Agmatine, by improving neuroplasticity markers and inducing Nrf2, prevents corticosterone-induced depressive-like behavior in mice AE Freitas, J Egea, I Buendia, V Gómez-Rangel, E Parada, E Navarro, ... Molecular neurobiology 53 (5), 3030-3045, 2016 | 99 | 2016 |
Microglial HO‐1 induction by curcumin provides antioxidant, antineuroinflammatory, and glioprotective effects E Parada, I Buendia, E Navarro, C Avendaño, J Egea, MG López Molecular nutrition & food research 59 (9), 1690-1700, 2015 | 78 | 2015 |
Heme-Oxygenase I and PCG-1α Regulate Mitochondrial Biogenesis via Microglial Activation of Alpha7 Nicotinic Acetylcholine Receptors Using PNU282987 E Navarro, L Gonzalez-Lafuente, I Pérez-Liébana, I Buendia, ... Antioxidants & redox signaling 27 (2), 93-105, 2017 | 69 | 2017 |
Agmatine induces Nrf2 and protects against corticosterone effects in hippocampal neuronal cell line AE Freitas, J Egea, I Buendía, E Navarro, P Rada, A Cuadrado, ... Molecular neurobiology 51 (3), 1504-1519, 2015 | 63 | 2015 |
Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase I induction E Navarro, I Buendia, E Parada, R León, P Jansen-Duerr, H Pircher, ... Biochemical pharmacology 97 (4), 473-481, 2015 | 47 | 2015 |
Positive allosteric modulation of alpha‐7 nicotinic receptors promotes cell death by inducing Ca2+ release from the endoplasmic reticulum M Guerra‐Álvarez, AJ Moreno‐Ortega, E Navarro, JC Fernández‐Morales, ... Journal of neurochemistry 133 (3), 309-319, 2015 | 46 | 2015 |
Melatonin–sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a ‘drug–prodrug’mechanism of action J Egea, I Buendia, E Parada, E Navarro, P Rada, A Cuadrado, MG López, ... British journal of pharmacology 172 (7), 1807-1821, 2015 | 46 | 2015 |
New melatonin–cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotection I Buendia, E Navarro, P Michalska, I Gameiro, J Egea, S Abril, A López, ... Future medicinal chemistry 7 (15), 1961-1969, 2015 | 42 | 2015 |
Subthreshold concentrations of melatonin and galantamine improves pathological AD-hallmarks in hippocampal organotypic cultures I Buendia, E Parada, E Navarro, R Leon, P Negredo, J Egea, MG Lopez Molecular neurobiology 53 (5), 3338-3348, 2016 | 35 | 2016 |
The Melatonin–N,N-Dibenzyl(N-methyl)amine Hybrid ITH91/IQM157 Affords Neuroprotection in an in Vitro Alzheimer’s Model via Hemo-oxygenase-1 Induction I Buendia, J Egea, E Parada, E Navarro, R León, MI Rodríguez-Franco, ... ACS chemical neuroscience 6 (2), 288-296, 2015 | 33 | 2015 |
Multi-omic insights into Parkinson's Disease: From genetic associations to functional mechanisms BM Schilder, E Navarro, T Raj Neurobiology of disease, 105580, 2021 | 23 | 2021 |
Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells E Navarro, E Udine, KP Lopes, M Parks, G Riboldi, BM Schilder, ... Nature Aging 1 (9), 850-863, 2021 | 21 | 2021 |
Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs S Ramdhani, E Navarro, E Udine, AG Efthymiou, BM Schilder, M Parks, ... PLoS genetics 16 (2), e1008549, 2020 | 20 | 2020 |
Transcriptome deregulation of peripheral monocytes and whole blood in GBA-related Parkinson’s disease GM Riboldi, RA Vialle, E Navarro, E Udine, K de Paiva Lopes, ... Molecular neurodegeneration 17 (1), 1-17, 2022 | 17 | 2022 |