Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of toxicology 91 (11), 3477-3505, 2017 | 258 | 2017 |
Toxicogenomics directory of chemically exposed human hepatocytes M Grinberg, RM Stöber, K Edlund, E Rempel, P Godoy, R Reif, A Widera, ... Archives of toxicology 88 (12), 2261-2287, 2014 | 137 | 2014 |
Collaborative development of predictive toxicology applications B Hardy, N Douglas, C Helma, M Rautenberg, N Jeliazkova, V Jeliazkov, ... Journal of cheminformatics 2 (1), 1-29, 2010 | 123 | 2010 |
Evaluation of inhalation TTC values with the database RepDose SE Escher, I Tluczkiewicz, M Batke, A Bitsch, C Melber, ED Kroese, ... Regulatory Toxicology and Pharmacology 58 (2), 259-274, 2010 | 73 | 2010 |
Legacy data sharing to improve drug safety assessment: the eTOX project F Sanz, F Pognan, T Steger-Hartmann, C Díaz, M Cases, M Pastor, ... Nature reviews Drug discovery 16 (12), 811-812, 2017 | 57 | 2017 |
Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project SE Escher, H Kamp, SH Bennekou, A Bitsch, C Fisher, R Graepel, ... Archives of toxicology 93 (12), 3643-3667, 2019 | 54 | 2019 |
Improvement of the Cramer classification for oral exposure using the database TTC RepDose–a strategy description I Tluczkiewicz, HE Buist, MT Martin, I Mangelsdorf, SE Escher Regulatory Toxicology and Pharmacology 61 (3), 340-350, 2011 | 49 | 2011 |
Toxicology ontology perspectives B Hardy, G Apic, P Carthew, D Clark, D Cook, I Dix, S Escher, J Hastings, ... ALTEX-Alternatives to animal experimentation 29 (2), 139-156, 2012 | 41 | 2012 |
Data quality assessment for in silico methods: a survey of approaches and needs M Nendza, T Aldenberg, E Benfenati, R Benigni, MTD Cronin, S Escher, ... Issues in Toxicology, 59-117, 2010 | 39 | 2010 |
Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology C Rovida, T Barton-Maclaren, E Benfenati, F Caloni, C Chandrasekera, ... Alternatives to Animal Experimentation: ALTEX 37 (4), 579-606, 2020 | 38 | 2020 |
Evaluation of time extrapolation factors based on the database RepDose M Batke, S Escher, S Hoffmann-Doerr, C Melber, H Messinger, ... Toxicology letters 205 (2), 122-129, 2011 | 37 | 2011 |
The application of new HARD-descriptor available from the CORAL software to building up NOAEL models AP Toropova, AA Toropov, M Marzo, SE Escher, JL Dorne, N Georgiadis, ... Food and Chemical Toxicology 112, 544-550, 2018 | 35 | 2018 |
OpenTox predictive toxicology framework: toxicological ontology and semantic media wiki-based OpenToxipedia O Tcheremenskaia, R Benigni, I Nikolova, N Jeliazkova, SE Escher, ... Journal of biomedical semantics 3 (1), 1-17, 2012 | 33 | 2012 |
Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes M Grinberg, RM Stöber, W Albrecht, K Edlund, M Schug, P Godoy, ... Archives of toxicology 92 (12), 3517-3533, 2018 | 32 | 2018 |
OSIRIS, a quest for proof of principle for integrated testing strategies of chemicals for four human health endpoints T Vermeire, T Aldenberg, H Buist, S Escher, I Mangelsdorf, E Pauné, ... Regulatory Toxicology and Pharmacology 67 (2), 136-145, 2013 | 32 | 2013 |
A toxicology ontology roadmap B Hardy, G Apic, P Carthew, D Clark, D Cook, I Dix, S Escher, J Hastings, ... ALTEX-Alternatives to animal experimentation 29 (2), 129-137, 2012 | 30 | 2012 |
Exposure-based waiving under REACH T Vermeire, M van de Bovenkamp, YB de Bruin, C Delmaar, ... Regulatory toxicology and pharmacology 58 (3), 408-420, 2010 | 29 | 2010 |
Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected n-alkanols TW Schultz, KR Przybylak, AN Richarz, CL Mellor, SE Escher, ... Computational Toxicology 2, 12-19, 2017 | 26 | 2017 |
Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected β-olefinic alcohols KR Przybylak, TW Schultz, AN Richarz, CL Mellor, SE Escher, ... Computational Toxicology 1, 22-32, 2017 | 25 | 2017 |
Comparing in vitro human liver models to in vivo human liver using RNA-Seq R Gupta, Y Schrooders, D Hauser, M van Herwijnen, W Albrecht, ... Archives of toxicology 95 (2), 573-589, 2021 | 21 | 2021 |