Zheng Liangzhen
Zheng Liangzhen
Shanghai Zelixir Biotech
Verified email at
Cited by
Cited by
Onionnet: a multiple-layer intermolecular-contact-based convolutional neural network for protein–ligand binding affinity prediction
L Zheng, J Fan, Y Mu
ACS omega 4 (14), 15956-15965, 2019
Structure and interactions of a host defense antimicrobial peptide thanatin in lipopolysaccharide micelles reveal mechanism of bacterial cell agglutination
S Sinha, L Zheng, Y Mu, WJ Ng, S Bhattacharjya
Scientific reports 7 (1), 17795, 2017
OnionNet-2: a convolutional neural network model for predicting protein-ligand binding affinity based on residue-atom contacting shells
Z Wang, L Zheng, Y Liu, Y Qu, YQ Li, M Zhao, Y Mu, W Li
Frontiers in chemistry 9, 753002, 2021
Improving protein–ligand docking and screening accuracies by incorporating a scoring function correction term
L Zheng, J Meng, K Jiang, H Lan, Z Wang, M Lin, W Li, H Guo, Y Wei, ...
Briefings in Bioinformatics 23 (3), bbac051, 2022
Comprehensive Analysis of ERK1/2 Substrates for Potential Combination Immunotherapies
L Yang, L Zheng, WJ Chng, JL Ding
Trends in Pharmacological Sciences 40 (11), 2019
E2Efold-3D: end-to-end deep learning method for accurate de novo RNA 3D structure prediction
T Shen, Z Hu, Z Peng, J Chen, P Xiong, L Hong, L Zheng, Y Wang, I King, ...
arXiv preprint arXiv:2207.01586, 2022
Molecular dynamics and simulation
L Zheng, AA Alhossary, CK Kwoh, Y Mu
Academic Press, 2019
Phospho‐regulation of intrinsically disordered proteins for actin assembly and endocytosis
Y Miao, T Tipakornsaowapak, L Zheng, Y Mu, E Lewellyn
The FEBS journal 285 (15), 2762-2784, 2018
Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast
Y Miao, X Han, L Zheng, Y Xie, Y Mu, JR Yates III, DG Drubin
Nature communications 7 (1), 11265, 2016
When homologous sequences meet structural decoys: Accurate contact prediction by tFold in CASP14—(tFold for CASP14 contact prediction)
T Shen, J Wu, H Lan, L Zheng, J Pei, S Wang, W Liu, J Huang
Proteins: Structure, Function, and Bioinformatics 89 (12), 1901-1910, 2021
A fully differentiable ligand pose optimization framework guided by deep learning and a traditional scoring function
Z Wang, L Zheng, S Wang, M Lin, Z Wang, AWK Kong, Y Mu, Y Wei, W Li
Briefings in Bioinformatics 24 (1), bbac520, 2023
Exploring flexibility of progesterone receptor ligand binding domain using molecular dynamics
L Zheng, VC Lin, Y Mu
PloS one 11 (11), e0165824, 2016
Structure prediction of the entire proteome of monkeypox variants
L Zheng, J Meng, M Lin, R Lv, H Cheng, L Zou, J Sun, LX Li, R Ren, ...
Acta Materia Medica 1 (2), 260-264, 2022
Incorporating GC pair-recognizing guanidinium into PNAs for sequence and structure specific recognition of dsRNAs over dsDNAs and ssRNAs
MS Krishna, Z Wang, L Zheng, J Bowry, AAL Ong, Y Mu, M Prabakaran, ...
Biochemistry 58 (36), 3777-3788, 2019
Dynamics changes of CRISPR-Cas9 systems induced by high fidelity mutations
L Zheng, J Shi, Y Mu
Physical Chemistry Chemical Physics 20 (43), 27439-27448, 2018
Boosting the predictive performance with aqueous solubility dataset curation
J Meng, P Chen, M Wahib, M Yang, L Zheng, Y Wei, S Feng, W Liu
Scientific Data 9 (1), 71, 2022
Application of variational graph encoders as an effective generalist algorithm in computer-aided drug design
HYI Lam, R Pincket, H Han, XE Ong, Z Wang, J Hinks, Y Wei, W Li, ...
Nature Machine Intelligence 5 (7), 754-764, 2023
fastmsa: Accelerating multiple sequence alignment with dense retrieval on protein language
L Hong, S Sun, L Zheng, Q Tan, Y Li
bioRxiv, 2021.12. 20.473431, 2021
Ligand binding induces agonistic-like conformational adaptations in helix 12 of progesterone receptor ligand binding domain
L Zheng, K Xia, Y Mu
Frontiers in Chemistry 7, 315, 2019
zPoseScore model for accurate and robust protein–ligand docking pose scoring in CASP15
Tao Shen, Fuxu Liu, Zechen Wang, Jinyuan Sun, Yifan Bu, Jintao Meng, Weihua ...
Proteins: Structure, Function and Bioinformatics 1 (13), 2023
The system can't perform the operation now. Try again later.
Articles 1–20