Manuel Holtgrewe
Manuel Holtgrewe
Core Unit Bioinformatics, Berlin Institute of Health
Verified email at bihealth.de - Homepage
Title
Cited by
Cited by
Year
Bioconda: sustainable and comprehensive software distribution for the life sciences
B Grüning, R Dale, A Sjödin, BA Chapman, J Rowe, CH Tomkins-Tinch, ...
Nature methods 15 (7), 475-476, 2018
4692018
Mason: a read simulator for second generation sequencing data
M Holtgrewe
2012010
Next-generation diagnostics and disease-gene discovery with the Exomiser
D Smedley, JOB Jacobsen, M Jäger, S Köhler, M Holtgrewe, M Schubach, ...
Nature protocols 10 (12), 2004-2015, 2015
1892015
RazerS 3: faster, fully sensitive read mapping
D Weese, M Holtgrewe, K Reinert
Bioinformatics 28 (20), 2592-2599, 2012
1542012
Engineering a scalable high quality graph partitioner
M Holtgrewe, P Sanders, C Schulz
2010 IEEE International Symposium on Parallel & Distributed Processing …, 2010
1182010
A novel and well-defined benchmarking method for second generation read mapping
M Holtgrewe, AK Emde, D Weese, K Reinert
BMC bioinformatics 12 (1), 1-10, 2011
1002011
Sustainable data analysis with Snakemake
F Mölder, KP Jablonski, B Letcher, MB Hall, CH Tomkins-Tinch, V Sochat, ...
F1000Research 10, 2021
732021
Fiona: a parallel and automatic strategy for read error correction
MH Schulz, D Weese, M Holtgrewe, V Dimitrova, S Niu, K Reinert, ...
Bioinformatics 30 (17), i356-i363, 2014
732014
Genome alignment with graph data structures: a comparison
B Kehr, K Trappe, M Holtgrewe, K Reinert
BMC bioinformatics 15 (1), 1-20, 2014
442014
Hi-C identifies complex genomic rearrangements and TAD-shuffling in developmental diseases
US Melo, R Schöpflin, R Acuna-Hidalgo, MA Mensah, B Fischer-Zirnsak, ...
The American Journal of Human Genetics 106 (6), 872-884, 2020
342020
Simple and fast nearest neighbor search
M Birn, M Holtgrewe, P Sanders, J Singler
2010 Proceedings of the Twelfth Workshop on Algorithm Engineering and …, 2010
222010
VarFish: comprehensive DNA variant analysis for diagnostics and research
M Holtgrewe, O Stolpe, M Nieminen, S Mundlos, A Knaus, U Kornak, ...
Nucleic acids research 48 (W1), W162-W169, 2020
212020
Methods for the detection and assembly of novel sequence in high-throughput sequencing data
M Holtgrewe, L Kuchenbecker, K Reinert
Bioinformatics 31 (12), 1904-1912, 2015
202015
Pathogenic variants in USP7 cause a neurodevelopmental disorder with speech delays, altered behavior, and neurologic anomalies
MD Fountain, DS Oleson, ME Rech, L Segebrecht, JV Hunter, ...
Genetics in medicine 21 (8), 1797-1807, 2019
162019
Multisite de novo mutations in human offspring after paternal exposure to ionizing radiation
M Holtgrewe, A Knaus, G Hildebrand, JT Pantel, MR de Los Santos, ...
Scientific reports 8 (1), 1-5, 2018
152018
Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3
J Kühnisch, C Herbst, N Al‐Wakeel‐Marquard, J Dartsch, M Holtgrewe, ...
Clinical genetics 96 (6), 549-559, 2019
122019
Computational Exome and Genome Analysis
PN Robinson, RM Piro, M Jager
CRC Press, 2017
112017
Interpretable clinical genomics with a likelihood ratio paradigm
PN Robinson, V Ravanmehr, JOB Jacobsen, D Danis, XA Zhang, ...
The American Journal of Human Genetics 107 (3), 403-417, 2020
102020
Paroxysmal tonic upgaze: A heterogeneous clinical condition responsive to carbonic anhydrase inhibition
A Quade, A Thiel, I Kurth, M Holtgrewe, M Elbracht, D Beule, ...
European Journal of Paediatric Neurology 25, 181-186, 2020
92020
Investigating APOE, APP-Aβ metabolism genes and Alzheimer’s disease GWAS hits in brain small vessel ischemic disease
S Blumenau, M Foddis, S Müller, M Holtgrewe, K Bentele, D Berchtold, ...
Scientific reports 10 (1), 1-14, 2020
62020
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Articles 1–20