| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2594 | 2019 |
| Oxidative damage is the earliest event in Alzheimer disease A Nunomura, G Perry, G Aliev, K Hirai, A Takeda, EK Balraj, PK Jones, ... Journal of Neuropathology & Experimental Neurology 60 (8), 759-767, 2001 | 2409 | 2001 |
| Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice RA Cherny, CS Atwood, ME Xilinas, DN Gray, WD Jones, CA McLean, ... Neuron 30 (3), 665-676, 2001 | 1891 | 2001 |
| Mitochondrial abnormalities in Alzheimer's disease K Hirai, G Aliev, A Nunomura, H Fujioka, RL Russell, CS Atwood, ... Journal of Neuroscience 21 (9), 3017-3023, 2001 | 1701 | 2001 |
| The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction X Huang, CS Atwood, MA Hartshorn, G Multhaup, LE Goldstein, ... Biochemistry 38 (24), 7609-7616, 1999 | 1443 | 1999 |
| Dramatic aggregation of Alzheimer Aβ by Cu (II) is induced by conditions representing physiological acidosis CS Atwood, RD Moir, X Huang, RC Scarpa, NME Bacarra, DM Romano, ... Journal of Biological Chemistry 273 (21), 12817-12826, 1998 | 1339 | 1998 |
| Cu (II) potentiation of Alzheimer Aβ neurotoxicity: correlation with cell-free hydrogen peroxide production and metal reduction X Huang, MP Cuajungco, CS Atwood, MA Hartshorn, JDA Tyndall, ... Journal of Biological Chemistry 274 (52), 37111-37116, 1999 | 1018 | 1999 |
| Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 993 | 2017 |
| Characterization of copper interactions with Alzheimer amyloid β peptides: identification of an attomolar‐affinity copper binding site on amyloid β1‐42 CS Atwood, RC Scarpa, X Huang, RD Moir, WD Jones, DP Fairlie, ... Journal of neurochemistry 75 (3), 1219-1233, 2000 | 843 | 2000 |
| Metal binding and oxidation of amyloid-β within isolated senile plaque cores: Raman microscopic evidence J Dong, CS Atwood, VE Anderson, SL Siedlak, MA Smith, G Perry, ... Biochemistry 42 (10), 2768-2773, 2003 | 724 | 2003 |
| Aqueous dissolution of Alzheimer's disease Aβ amyloid deposits by biometal depletion RA Cherny, JT Legg, CA McLean, DP Fairlie, X Huang, CS Atwood, ... Journal of Biological Chemistry 274 (33), 23223-23228, 1999 | 677 | 1999 |
| Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc MP Cuajungco, LE Goldstein, A Nunomura, MA Smith, JT Lim, CS Atwood, ... Journal of Biological Chemistry 275 (26), 19439-19442, 2000 | 564 | 2000 |
| Effects of hormone therapy on cognition and mood in recently postmenopausal women: findings from the randomized, controlled KEEPS–cognitive and affective study CE Gleason, NM Dowling, W Wharton, JAE Manson, VM Miller, ... PLoS medicine 12 (6), e1001833, 2015 | 526 | 2015 |
| Redox-active iron mediates amyloid-β toxicity CA Rottkamp, AK Raina, X Zhu, E Gaier, AI Bush, CS Atwood, M Chevion, ... Free Radical Biology and Medicine 30 (4), 447-450, 2001 | 496 | 2001 |
| Copper mediates dityrosine cross-linking of Alzheimer's amyloid-β CS Atwood, G Perry, H Zeng, Y Kato, WD Jones, KQ Ling, X Huang, ... Biochemistry 43 (2), 560-568, 2004 | 476 | 2004 |
| Is oxidative damage the fundamental pathogenic mechanism of Alzheimer’s and other neurodegenerative diseases? G Perry, A Nunomura, K Hirai, X Zhu, M Prez, J Avila, RJ Castellani, ... Free Radical Biology and Medicine 33 (11), 1475-1479, 2002 | 435 | 2002 |
| Zinc-induced Alzheimer's Aβ1–40 aggregation is mediated by conformational factors X Huang, CS Atwood, RD Moir, MA Hartshorn, JP Vonsattel, RE Tanzi, ... Journal of Biological Chemistry 272 (42), 26464-26470, 1997 | 431 | 1997 |
| Amyloid-β: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-β CS Atwood, ME Obrenovich, T Liu, H Chan, G Perry, MA Smith, ... Brain Research Reviews 43 (1), 1-16, 2003 | 428 | 2003 |
| Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the ‘two hit’hypothesis X Zhu, RJ Castellani, A Takeda, A Nunomura, CS Atwood, G Perry, ... Mechanisms of ageing and development 123 (1), 39-46, 2001 | 394 | 2001 |
| Maintenance of villus height and crypt depth, and enhancement of disaccharide digestion and monosaccharide absorption, in piglets fed on cows' whole milk after weaning JR Pluske, MJ Thompson, CS Atwood, PH Bird, IH Williams, PE Hartmann British Journal of Nutrition 76 (3), 409-422, 1996 | 378 | 1996 |
George PerryProfessor of Neuroscience, Developmental and Regenerative Biology and Chemistry, University of TexasVerified email at utsa.edu
