Real-time PCR for mRNA quantitation ML Wong, JF Medrano Biotechniques 39 (1), 75-85, 2005 | 2708 | 2005 |
A large electronic-health-record-based genome-wide study of serum lipids TJ Hoffmann, E Theusch, T Haldar, DK Ranatunga, E Jorgenson, ... Nature genetics 50 (3), 401-413, 2018 | 270 | 2018 |
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy LM Mangravite, BE Engelhardt, MW Medina, JD Smith, CD Brown, ... Nature 502 (7471), 377-380, 2013 | 229 | 2013 |
Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin … RM Krauss, LM Mangravite, JD Smith, MW Medina, D Wang, X Guo, ... Circulation 117 (12), 1537-1544, 2008 | 184 | 2008 |
Alternative splicing of 3-hydroxy-3-methylglutaryl coenzyme A reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin M Wong Medina, FG Geo, W Ruan, JI Rotter, RM Krauss Circulation 118 (4), 357-362, 2008 | 164 | 2008 |
Pharmacogenomic discovery using cell-based models M Welsh, L Mangravite, MW Medina, K Tantisira, W Zhang, RS Huang, ... Pharmacological reviews 61 (4), 413-429, 2009 | 135 | 2009 |
Cardiovascular pharmacogenomics DM Roden, JA Johnson, SE Kimmel, RM Krauss, MW Medina, ... Circulation research 109 (7), 807-820, 2011 | 87 | 2011 |
Combined Influence of LDLR and HMGCR Sequence Variation on Lipid-Lowering Response to Simvastatin LM Mangravite, MW Medina, J Cui, S Pressman, JD Smith, MJ Rieder, ... Arteriosclerosis, thrombosis, and vascular biology 30 (7), 1485-1492, 2010 | 87 | 2010 |
Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake MW Medina, F Gao, D Naidoo, LL Rudel, RE Temel, AL McDaniel, ... PloS one 6 (4), e19420, 2011 | 84 | 2011 |
HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism CY Yu, E Theusch, K Lo, LM Mangravite, D Naidoo, M Kutilova, ... Human molecular genetics 23 (2), 319-332, 2014 | 72 | 2014 |
The role of HMGCR alternative splicing in statin efficacy MW Medina, RM Krauss Trends in cardiovascular medicine 19 (5), 173-177, 2009 | 69 | 2009 |
CYP3A4* 22 and CYP3A5* 3 are associated with increased levels of plasma simvastatin concentrations in the cholesterol and pharmacogenetics study cohort JP Kitzmiller, JA Luzum, D Baldassarre, RM Krauss, MW Medina Pharmacogenetics and genomics 24 (10), 486-491, 2014 | 63 | 2014 |
Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol MI Alvarez, LC Glover, P Luo, L Wang, E Theusch, SH Oehlers, ... Proceedings of the National Academy of Sciences 114 (37), E7746-E7755, 2017 | 54 | 2017 |
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function F Gao, HE Ihn, MW Medina, RM Krauss Human molecular genetics 22 (7), 1424-1431, 2013 | 53 | 2013 |
RHOA is a modulator of the cholesterol-lowering effects of statin MW Medina, E Theusch, D Naidoo, F Bauzon, K Stevens, LM Mangravite, ... PLoS genetics 8 (11), e1003058, 2012 | 46 | 2012 |
GATM polymorphism associated with the risk for statin-induced myopathy does not replicate in case-control analysis of 715 dyslipidemic individuals JA Luzum, JP Kitzmiller, PJ Isackson, C Ma, MW Medina, AM Dauki, ... Cell metabolism 21 (4), 622-627, 2015 | 42 | 2015 |
A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT CC Brown, TM Havener, MW Medina, JT Auman, LM Mangravite, ... Pharmacogenetics and genomics 22 (11), 796-802, 2012 | 41 | 2012 |
Characterization of statin low-density lipoprotein cholesterol dose-response using electronic health records in a large population-based cohort A Oni-Orisan, TJ Hoffmann, D Ranatunga, MW Medina, E Jorgenson, ... Circulation: Genomic and Precision Medicine 11 (9), e002043, 2018 | 39 | 2018 |
Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines A Chhibber, CE French, SW Yee, ER Gamazon, E Theusch, X Qin, ... The pharmacogenomics journal 17 (2), 137-145, 2017 | 37 | 2017 |
The relationship between HMGCR genetic variation, alternative splicing, and statin efficacy MW Medina Discovery medicine 9 (49), 495-499, 2010 | 34 | 2010 |