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Guowei Gu
Guowei Gu
Ph.D and Pharm.B
Verified email at bcm.edu
Title
Cited by
Cited by
Year
Estrogen receptor (ER) α mutations in breast cancer: hidden in plain sight
SAW Fuqua, G Gu, Y Rechoum
Breast cancer research and treatment 144, 11-19, 2014
2272014
ESR1 mutations in breast cancer
D Dustin, G Gu, SAW Fuqua
Cancer 125 (21), 3714-3728, 2019
2072019
Targeted therapy for breast cancer and molecular mechanisms of resistance to treatment
G Gu, D Dustin, SAW Fuqua
Current opinion in pharmacology 31, 97-103, 2016
1752016
Evidence that leptin through STAT and CREB signaling enhances cyclin D1 expression and promotes human endometrial cancer proliferation
S Catalano, C Giordano, P Rizza, G Gu, I Barone, D Bonofiglio, ...
Journal of cellular physiology 218 (3), 490-500, 2009
1362009
Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERα/Sp1‐mediated p53 activation
G Gu, I Barone, L Gelsomino, C Giordano, D Bonofiglio, G Statti, ...
Journal of cellular physiology 227 (10), 3363-3372, 2012
932012
Rapid estradiol/ERα signaling enhances aromatase enzymatic activity in breast cancer cells
S Catalano, I Barone, C Giordano, P Rizza, H Qi, G Gu, R Malivindi, ...
Molecular endocrinology 23 (10), 1634-1645, 2009
912009
ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling
L Gelsomino, G Gu, Y Rechoum, AR Beyer, SM Pejerrey, A Tsimelzon, ...
Breast cancer research and treatment 157, 253-265, 2016
882016
Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells
S Catalano, R Malivindi, C Giordano, G Gu, S Panza, D Bonofiglio, ...
Journal of biological chemistry 285 (8), 5581-5593, 2010
722010
Loss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor α
I Barone, L Brusco, G Gu, J Selever, A Beyer, KR Covington, A Tsimelzon, ...
Journal of the National Cancer Institute 103 (7), 538-552, 2011
632011
Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells
J Selever, G Gu, MT Lewis, A Beyer, MH Herynk, KR Covington, ...
Clinical Cancer Research 17 (20), 6510-6521, 2011
622011
Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERα-positive breast cancer
A Ciupek, Y Rechoum, G Gu, L Gelsomino, AR Beyer, L Brusco, ...
Breast cancer research and treatment 154, 225-237, 2015
612015
Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets
LA Gates, G Gu, Y Chen, AD Rohira, JT Lei, RA Hamilton, Y Yu, ...
Oncogene 37 (33), 4581-4598, 2018
602018
Mutations in the estrogen receptor alpha hormone binding domain promote stem cell phenotype through notch activation in breast cancer cell lines
L Gelsomino, S Panza, C Giordano, I Barone, G Gu, E Spina, S Catalano, ...
Cancer letters 428, 12-20, 2018
552018
The Impact of ESR1 Mutations on the Treatment of Metastatic Breast Cancer
SM Pejerrey, D Dustin, JA Kim, G Gu, Y Rechoum, SAW Fuqua
Hormones and Cancer 9, 215-228, 2018
452018
Targeting thyroid hormone receptor beta in triple-negative breast cancer
G Gu, L Gelsomino, KR Covington, AR Beyer, J Wang, Y Rechoum, ...
Breast cancer research and treatment 150, 535-545, 2015
432015
Fas ligand expression in TM4 Sertoli cells is enhanced by estradiol “in situ” production
S Catalano, P Rizza, G Gu, I Barone, C Giordano, S Marsico, I Casaburi, ...
Journal of cellular physiology 211 (2), 448-456, 2007
312007
Hormonal modulation of ESR1 mutant metastasis
G Gu, L Tian, SK Herzog, Y Rechoum, L Gelsomino, M Gao, L Du, JA Kim, ...
Oncogene 40 (5), 997-1011, 2021
262021
The SMRT coregulator enhances growth of estrogen receptor-α-positive breast cancer cells by promotion of cell cycle progression and inhibition of apoptosis
JK Blackmore, S Karmakar, G Gu, V Chaubal, L Wang, W Li, CL Smith
Endocrinology 155 (9), 3251-3261, 2014
232014
ESR1 Mutations in Breast Cancer: Proof-of-Concept Challenges Clinical Action
G Gu, SAW Fuqua
Clinical Cancer Research 22 (5), 1034-1036, 2016
192016
Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity
F Stossi, RD Dandekar, MG Mancini, G Gu, SAW Fuqua, A Nardone, ...
Nucleic acids research 48 (4), 1800-1810, 2020
182020
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